Midline Catheter Versus Long Peripheral Intravenous Catheter in Hospitalized Adult Patients

NCT05884294 | Completed

• 1 other identifier: 2022-0363
• Study Type: interventional
• Target: 102
• Locations: 1 country
• Sites: 1

Brief Summary

This research seeks to compare two types of vascular access (catheters that are inserted into the vein) for patient treatment during hospitalization. This research will evaluate how long each catheter lasts before presenting problems that may lead to its removal from the vein (the most common are swelling on the site of the catheter, clogging of the catheter, infections, or other less common problems. Each patient will be randomly selected to receive either catheter. In this study, we will also estimate how much each patient will spend if any of the problems mentioned occur.

Conditions

Vascular Access Devices

Keywords

vascular access device; midline catheter; long Peripheral Intravenous Catheter

Outcome Measures

Primary Outcomes (1)

• Lenght of time of vascular access without isolated or combined complications.

  Time in days.

  up to 30 days, end of therapy or withdrawal due to any complication

Secondary Outcomes (1)

• First-attempt puncture success

  up to 30 days or end of therapy

Other Outcomes (1)

• Economic analysis

  30 days or end of therapy.

Study Arms (2)

PowerGlide Pro Midline catheter.

EXPERIMENTAL

The Intervention Group will be represented by hospitalized adult clinical patients who have been identified with difficult intravenous access. These patients will receive an ultrasound-guided insertion of the PowerGlide ProTM Midline 20G (10 cm).

Device: PowerGlide Pro Midline catheter.

Introcan Safety Deep Access long peripheral venous catheter.

NO INTERVENTION

The control group will be subjected to the same selection criteria as the patients in the intervention group; however, they will receive an ultrasound-guided insertion of a long peripheral venous catheter Introcan Safety Deep Access 20G (6.4 cm).

Interventions

PowerGlide Pro Midline catheter. DEVICE

The Intervention Group will be represented by hospitalized adult clinical patients who have been identified with difficult intravenous access. These patients will receive an ultrasound-guided insertion of the PowerGlide ProTM Midline 20G (10 cm).

PowerGlide Pro Midline catheter.

Eligibility Criteria

• Age: 18 Years+
• Sex: all
• Healthy Volunteers: No
• Age Groups: Adult (18-64), Older Adult (65+)

* patients hospitalized in a clinical ward unit; * indicated for continuous or intermittent intravenous therapy more than five days; * identified with difficult intravenous access.

Contact the study team to discuss eligibility requirements. They can help determine if this study is right for you.

Sponsors & Collaborators

• Hospital de Clinicas de Porto Alegre: lead

Study Sites (1)

Hospital de Clínicas de Porto Alegre

Porto Alegre, Rio Grande do Sul, 90035 903, Brazil

Location

Related Publications (1)

• Teixeira TO, Hansel LA, Ceratti RDN, Brum ID, Fernandes AGDS, Saline CG, Junges M, Rabelo-Silva ER. Midline catheter (10 cm) versus long peripheral intravenous catheter (6.4 cm): Randomized clinical trial protocol with economic analysis. PLoS One. 2025 Apr 24;20(4):e0319587. doi: 10.1371/journal.pone.0319587. eCollection 2025.

  PMID: 40273075 DERIVED

Study Officials

• Eneida R Rabelo da Silva, ScD

  Hospital de Clínicas de Porto Alegre

  PRINCIPAL INVESTIGATOR

Study Design

• Study Type: interventional
• Phase: not applicable
• Allocation: RANDOMIZED
• Masking: SINGLE
• Who Masked: OUTCOMES ASSESSOR
• Masking Details: This study will be blind to statistical analysis.
• Purpose: OTHER
• Intervention Model: PARALLEL
• Sponsor Type: OTHER
• Responsible Party: SPONSOR

Model Details: randomized, parallel, open, controlled, and single-center clinical trial.

Study Record Dates

• First Submitted: January 27, 2023
• First Posted: June 1, 2023
• Study Start: January 2, 2024
• Primary Completion: February 27, 2025
• Study Completion: March 1, 2025
• Last Updated: June 18, 2025

Record last verified: 2025-06

Data Sharing

• IPD Sharing: Will not share

Locations

BR (1)