The Acute Effects of Combined Caffeine and Sodium Bicarbonate Consumption on Isometric Mid-thigh Pull

NCT05883046 | Completed

• 1 other identifier: BozokU-SBF-IK-01
• Study Type: interventional
• Target: 19
• Locations: 1 country
• Sites: 1

Brief Summary

The aim of this study was to investigate the effects of isolated and combined caffeine and sodium bicarbonate consumption on acute isometric mid-thigh pull (IMTP) strength, and verify whether they are cumulative, neutral or subtractive.

Conditions

Athletes

Keywords

Caffeine; Sodium Bicarbonate; Isometric Contraction; Performance-Enhancing Substances

Outcome Measures

Primary Outcomes (1)

• Isometric Mid-Thigh Pull (IMTP)

  to investigate the effects of isolated and combined caffeine and sodium bicarbonate consumption on acute isometric mid-thigh pull (IMTP) strength, and verify whether they are cumulative, neutral or subtractive

  immediately after the intervention

Study Arms (5)

Baseline

OTHER

The control measurement was made as a baseline measurement without supplementation

Other: Baseline (Control)

Placebo

PLACEBO COMPARATOR

During Placebo conditions, participants consumed 20gr of maltodextrin (European origin, Alfasol®, Kimbiotek, Turkey).

Other: Placebo

Caffeine

EXPERIMENTAL

For Caffeine conditions, participants consumed 6 mg/kg of caffeine, obtained from dosing the content of 200 mg capsules (Nature's Supreme® Caffeine)

Other: Performance-Enhancing Substances

NaHCO3

EXPERIMENTAL

As for NaHCO3 conditions, participants consumed 0.3 g/kg of sodium bicarbonate (Alfasol®, Kimbiotek, Turkey) dissolved in water

Other: Performance-Enhancing Substances

Combined

EXPERIMENTAL

For the combined condition, (Caf+NaHCO3), 6 mg/kg of caffeine and 0.3 g/kg of sodium bicarbonate per kilogram of body weight of participants were consumed, after being dissolved together in water

Other: Performance-Enhancing Substances

Interventions

Performance-Enhancing Substances OTHER

All supplements were consumed 60 min before the isometric mid-thigh pull tests, to reach peak blood concentrations at evaluation time. Immediately after consumption, both Control and intervention participants rested in a quiet laboratory environment (Eskişehir Technical University, Laboratory of Human Athletic Performance), until the strength tests. Participants were previously informed verbally and in writing that they should abstain from caffeine consumption (any caffeine-containing beverages and foods, such as coffee or tea, energy drinks, cocoa and cocoa-containing foods, chocolate and chocolate-containing foods or caffeine-containing drugs) for at least 24 hours before

Caffeine; Combined; NaHCO3

Placebo OTHER

20gr of maltodextrin (European origin, Alfasol®, Kimbiotek, Turkey)

Placebo

Baseline (Control) OTHER

No supplement conditions

Baseline

Eligibility Criteria

• Age: 18 Years - 24 Years
• Sex: all
• Healthy Volunteers: Yes
• Age Groups: Adult (18-64)

You may qualify if:

• Being physically active and healthy
• Did not use ergogenic supplements in the last 3 months
• Did not consume high doses of caffeine (≤120-170 mg/d) were included in this study

You may not qualify if:

• Actively using supplements
• Did not perform maximal effort during performance tests
• Not using the supplements in the correct dose or vomiting after use

Sponsors & Collaborators

• Bozok University: lead

Study Sites (1)

Faculty of Sport Sciences Eskisehir Technical University

Eskişehir, Tepebasi, 26555, Turkey (Türkiye)

Location

MeSH Terms

Interventions

Performance-Enhancing Substances; BaseLine dental cement

Intervention Hierarchy (Ancestors)

Physiological Effects of Drugs; Pharmacologic Actions; Chemical Actions and Uses

Study Design

• Study Type: interventional
• Phase: not applicable
• Allocation: NON RANDOMIZED
• Masking: DOUBLE
• Who Masked: PARTICIPANT, INVESTIGATOR
• Masking Details: Supplement preparation, as well as the provision and management of blind conditions for both participants and investigators, were performed by a researcher (Celil KAÇOĞLU) who did not participate in the strength measurements.
• Purpose: OTHER
• Intervention Model: PARALLEL
• Sponsor Type: OTHER
• Responsible Party: PRINCIPAL INVESTIGATOR
• PI Title: Associate Professor

Model Details: subjects participated under 5 crossover conditions: control (without supplement) (Con), placebo (maltodextrin) (Pla), caffeine (Caf), sodium bicarbonate (NaHCO3) and caffeine+sodium bicarbonate (Caf+NaHCO3). The control measurement was made as a baseline measurement without supplementation.

Study Record Dates

• First Submitted: May 19, 2023
• First Posted: May 31, 2023
• Study Start: March 7, 2022
• Primary Completion: March 8, 2022
• Study Completion: March 12, 2022
• Last Updated: May 31, 2023

Record last verified: 2023-05

Data Sharing

• IPD Sharing: Will share
• Shared Documents: STUDY PROTOCOL, ANALYTIC CODE

Locations

TU (1)