NCT05882279

Brief Summary

This is a survey among pharmacists who have instructed NINLARO therapy in ixazomib, lenalidomide and dexamethasone (IRD) dosing to patients with relapsed/refractory multiple myeloma (rrMM). The main aims of the study are:

  • To assess the frequency of pharmacists who have provided patients with the contents of the RMP material for patients.
  • To assess the frequency of pharmacists who have obtained the RMP material for patients.
  • To evaluate the depth of understanding of proper usage of NINLARO among pharmacists.

Trial Health

87
On Track

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Enrollment
330

participants targeted

Target at P75+ for all trials

Timeline
Completed

Started Jun 2023

Geographic Reach
1 country

1 active site

Status
completed

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

Click on a node to explore related trials.

Study Timeline

Key milestones and dates

First Submitted

Initial submission to the registry

May 22, 2023

Completed
9 days until next milestone

First Posted

Study publicly available on registry

May 31, 2023

Completed
1 day until next milestone

Study Start

First participant enrolled

June 1, 2023

Completed
8 days until next milestone

Primary Completion

Last participant's last visit for primary outcome

June 9, 2023

Completed
Same day until next milestone

Study Completion

Last participant's last visit for all outcomes

June 9, 2023

Completed
1 year until next milestone

Results Posted

Study results publicly available

June 14, 2024

Completed
Last Updated

June 14, 2024

Status Verified

May 1, 2024

Enrollment Period

8 days

First QC Date

May 22, 2023

Results QC Date

May 23, 2024

Last Update Submit

May 23, 2024

Conditions

Keywords

Drug Therapy

Outcome Measures

Primary Outcomes (1)

  • Number of Pharmacists Who Had Provided Patients With the Contents of the Risk Management Plan (RMP) Material

    The NINLARO additional risk minimization measure (aRMM) effectiveness study questionnaire which was intended for pharmacists who instructed the dosing of IRD therapy to patients with relapsed/refractory multiple myeloma (RRMM). This outcome was based on the number of pharmacists who answered "Yes" to question 3; Do you instruct patients that they should take one capsule of NINLARO each time on an empty stomach for RRMM? Here, unit of measure: participants refer to pharmacists.

    Up to Day 9

Secondary Outcomes (3)

  • Number of Pharmacists Who Had Received the RMP Material for Patients

    Up to Day 9

  • Number of Pharmacist With Understanding of the Proper NINLARO Dosing Schedule

    Up to Day 9

  • Number of Pharmacist With Understanding of the Importance of Providing NINLARO Dosing Schedule

    Up to Day 9

Study Arms (1)

Pharmacists in Hospitals Prescribing NINLARO

Pharmacists included in Nikkei Research Access Panel who are active in clinical practice, with valid contact and who have instructed the dosing of NINLARO IRD therapy to patients with rrMM will self-administer a web-based survey. The questionnaires in the survey will be provided in Japanese.

Other: No Intervention

Interventions

This is a non-interventional study.

Pharmacists in Hospitals Prescribing NINLARO

Eligibility Criteria

Age18 Years+
Sexall
Healthy VolunteersNo
Age GroupsAdult (18-64), Older Adult (65+)
Sampling MethodNon-Probability Sample
Study Population

Pharmacists included in Nikkei Research Access Panel, active in clinical practice, and with valid contact details who belong to hospitals prescribing NINLARO and instructed the dosing of NINLARO in IRD therapy to patients with rrMM will be randomly selected to participate in the survey.

You may qualify if:

  • Who belong to hospitals prescribing NINLARO.
  • Who have instructed the dosing of NINLARO in IRD therapy to patients.

You may not qualify if:

  • None

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Study Sites (1)

Takeda selected site

Tokyo, Japan

Location

Related Links

MeSH Terms

Conditions

Multiple Myeloma

Condition Hierarchy (Ancestors)

Neoplasms, Plasma CellNeoplasms by Histologic TypeNeoplasmsHemostatic DisordersVascular DiseasesCardiovascular DiseasesParaproteinemiasBlood Protein DisordersHematologic DiseasesHemic and Lymphatic DiseasesHemorrhagic DisordersLymphoproliferative DisordersImmunoproliferative DisordersImmune System Diseases

Results Point of Contact

Title
Study Director
Organization
Takeda

Study Officials

  • Study Director

    Takeda

    STUDY DIRECTOR

Publication Agreements

PI is Sponsor Employee
No
Restriction Type
OTHER
Restrictive Agreement
Yes

Study Design

Study Type
observational
Observational Model
OTHER
Time Perspective
PROSPECTIVE
Sponsor Type
INDUSTRY
Responsible Party
SPONSOR

Study Record Dates

First Submitted

May 22, 2023

First Posted

May 31, 2023

Study Start

June 1, 2023

Primary Completion

June 9, 2023

Study Completion

June 9, 2023

Last Updated

June 14, 2024

Results First Posted

June 14, 2024

Record last verified: 2024-05

Data Sharing

IPD Sharing
Will share

Takeda provides access to the de-identified individual participant data (IPD) for eligible studies to aid qualified researchers in addressing legitimate scientific objectives (Takeda's data sharing commitment is available on https://clinicaltrials.takeda.com/takedas-commitment?commitment=5). These IPDs will be provided in a secure research environment following approval of a data sharing request, and under the terms of a data sharing agreement.

Shared Documents
STUDY PROTOCOL, SAP, ICF, CSR
Access Criteria
IPD from eligible studies will be shared with qualified researchers according to the criteria and process described on https://vivli.org/ourmember/takeda/. For approved requests, the researchers will be provided access to anonymized data (to respect patient privacy in line with applicable laws and regulations) and with information necessary to address the research objectives under the terms of a data sharing agreement.
More information

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