Premedication for Claustrophobic Patients for MRI Scan

NCT05876117 | Recruiting

• 1 other identifier: SalemAnes2022 MRI Premedicate
• Study Type: observational
• Target: 50
• Locations: 1 country
• Sites: 1

Brief Summary

Claustrophobia is an irrational fear of restriction and suffocation. It is a specific phobia, according to DSM 5. Claustrophobic patients may fear that restriction of their limbs will hinder their ability to move quickly towards safety. MRI may trigger claustrophobia, because this diagnostic procedure involves a patient laying in a narrow tube. Premedication before MRI scan may occasionally reduce claustrophobia. Prospective observational crossover study of claustrophobic patients who are undergoing MRI scan. At alternate MRI scan sessions, each patient receives rotational premedication using Lorazepam 1mg; or Clonidine tablet 0.2mg; or combined Clonidine 0.2mg + Lorazepam 1mg. Patient will use Claustrophobia Questionnaire, a validated tool, to collect data on the days before and after each MRI scan. CLQ is a patient-administered tool used to assess claustrophobia. In addition, patient will use General Anxiety Disorder Questionnaire, a validated tool, to collect data on the days before and after each MRI scan. GAD-7 is a patient-administered tool that is used to assess anxiety.

Conditions

Claustrophobia

Keywords

Claustrophobia MRI

Outcome Measures

Primary Outcomes (1)

• Rate of completion of MRI scan

  Patient is calm and cooperative, completes MRI scan

  12 weeks

Study Arms (1)

Claustrophobic adult patients

Claustrophobic adult patients who are undergoing MRI scan as part of chronic pain management.

Eligibility Criteria

• Age: 20 Years - 99 Years
• Sex: all
• Healthy Volunteers: Yes
• Age Groups: Adult (18-64), Older Adult (65+)
• Sampling Method: Non-Probability Sample

Study Population

Adult claustrophobic patients who are undergoing MRI scan as part of chronic pain management. Previous incomplete MRI because of claustrophobia.

You may qualify if:

• diagnosed with claustrophobia
• previous incomplete MRI because of claustrophobia
• adult patients
• good treatment compliance
• reliable Claustrophobia Questionnaire (CLQ) diary
• reliable General Anxiety Disorder Questionnaire (GAD) diary
• informed consent for diary review
• consent for clinical record quality assurance review

You may not qualify if:

• poor treatment compliance
• cognitive disorder
• inability to provide consent
• major neuropsychiatric disorder
• unreliable diary
• cannabis use
• excessive alcohol intake
• previous adverse/allergic reactions to clonidine
• previous adverse/allergic reactions to lorazepam

Sponsors & Collaborators

• Salem Anaesthesia Pain Clinic: lead

Study Sites (1)

Salem Anaesthesia Pain Clinic

Surrey, British Columbia, V3S 7J1, Canada

RECRUITING

MeSH Terms

Conditions

Claustrophobia

Condition Hierarchy (Ancestors)

Phobic Disorders; Anxiety Disorders; Mental Disorders

Study Officials

• Olu Bamgbade, MD,FRCPC

  Salem Anaesthesia Pain Clinic

  PRINCIPAL INVESTIGATOR

Central Study Contacts

Olu Bamgbade, MD,FRCPC

CONTACT

17786286600; salem.painclinic@gmail.com

Study Design

• Study Type: observational
• Observational Model: CASE CROSSOVER
• Time Perspective: PROSPECTIVE
• Sponsor Type: OTHER
• Responsible Party: SPONSOR

Study Record Dates

• First Submitted: May 5, 2023
• First Posted: May 25, 2023
• Study Start: July 4, 2020
• Primary Completion: December 31, 2025
• Study Completion: December 31, 2025
• Last Updated: January 27, 2025

Record last verified: 2025-01

Locations

CA (1)