NCT05874596

Brief Summary

A clustered randomized control trial to evaluate whether multi-aspect intervention based on an AI-aided clinical feedback system could improve the quality of EVT and functional outcome of patients.

Trial Health

87
On Track

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Enrollment
1,289

participants targeted

Target at P75+ for not_applicable

Timeline
Completed

Started Jun 2024

Shorter than P25 for not_applicable

Geographic Reach
1 country

1 active site

Status
completed

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

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Study Timeline

Key milestones and dates

First Submitted

Initial submission to the registry

May 2, 2023

Completed
23 days until next milestone

First Posted

Study publicly available on registry

May 25, 2023

Completed
1.1 years until next milestone

Study Start

First participant enrolled

June 30, 2024

Completed
2 months until next milestone

Primary Completion

Last participant's last visit for primary outcome

September 5, 2024

Completed
3 months until next milestone

Study Completion

Last participant's last visit for all outcomes

December 8, 2024

Completed
Last Updated

November 20, 2025

Status Verified

July 1, 2023

Enrollment Period

2 months

First QC Date

May 2, 2023

Last Update Submit

November 17, 2025

Conditions

Outcome Measures

Primary Outcomes (1)

  • Ratio of favorable functional outcome at 3 month

    Ratio of patients with mRS ≤ 3 at 3-month follow up

    3 months

Secondary Outcomes (10)

  • Ratio of good functional outcome at 3 month

    3 months

  • mRS score at 3 month

    3 months

  • Mortality at 3 month

    3 months

  • Ratio of hemorrhagic transformation at 24 hour

    24 hours

  • Ratio of symptomatic intracranial hemorrhage at 24 hour

    24 hours

  • +5 more secondary outcomes

Other Outcomes (2)

  • Ratio of favorable functional outcome at 3 month in patients within 6 hours of stroke onset

    3 months

  • Door to groin puncture time in patients within 6 hours of stroke onset

    24 hours

Study Arms (2)

Intervention

EXPERIMENTAL

AI-aided clinical feedback system coupled with multi-aspect intervention based on the Behaviour Change Wheel model

Behavioral: AI-aided clinical feedback system coupled with multi-aspect intervention basd on Behaviour Change Wheel model

Control

NO INTERVENTION

AI-aided clinical feedback system only

Interventions

Interventions are developed on a psychological model, the Behaviour Change Wheel (BCW) .The fundamental of BCW consists of three essential elements: capability, motivation, and opportunity. Improving individual's capability, providing motivation, and increasing opportunities are goals of behaviour change intervention. To achieve the goals, 9 intervention components have been proposed in the BCW framework, and 6 components will be used in current study.

Intervention

Eligibility Criteria

Age18 Years+
Sexall
Healthy VolunteersNo
Age GroupsAdult (18-64), Older Adult (65+)

You may qualify if:

  • Age \> 18
  • AIS patients receiving EVT within 24 hours of stroke onset
  • Written informed consent is obtained

You may not qualify if:

  • Patients refuse to participate in this study

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Study Sites (1)

Second Affiliated Hospital, School of Medicine, Zhejiang University

Hangzhou, China

Location

MeSH Terms

Conditions

Stroke

Condition Hierarchy (Ancestors)

Cerebrovascular DisordersBrain DiseasesCentral Nervous System DiseasesNervous System DiseasesVascular DiseasesCardiovascular Diseases

Study Officials

  • Zexin Chen

    Ethics committee the second affiliated hospital, school of medicine, Zhejiang University, China

    PRINCIPAL INVESTIGATOR

Study Design

Study Type
interventional
Phase
not applicable
Allocation
RANDOMIZED
Masking
DOUBLE
Who Masked
PARTICIPANT, OUTCOMES ASSESSOR
Purpose
TREATMENT
Intervention Model
PARALLEL
Sponsor Type
OTHER
Responsible Party
SPONSOR

Study Record Dates

First Submitted

May 2, 2023

First Posted

May 25, 2023

Study Start

June 30, 2024

Primary Completion

September 5, 2024

Study Completion

December 8, 2024

Last Updated

November 20, 2025

Record last verified: 2023-07

Data Sharing

IPD Sharing
Will not share

Locations