NCT05868590

Brief Summary

The aim of this study is to compare the plaque reduction efficacy of toothpaste to a marketed active magnesium toothpaste with single-use brushing in children.Our study will consist of 50 people between the ages of 9-12. 50 people will take part in both toothpaste groups.

Trial Health

35
At Risk

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Trial has exceeded expected completion date
Enrollment
50

participants targeted

Target at P25-P50 for not_applicable

Timeline
Completed

Started May 2023

Status
unknown

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

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Study Timeline

Key milestones and dates

First Submitted

Initial submission to the registry

April 26, 2023

Completed
26 days until next milestone

First Posted

Study publicly available on registry

May 22, 2023

Completed
4 days until next milestone

Study Start

First participant enrolled

May 26, 2023

Completed
8 months until next milestone

Primary Completion

Last participant's last visit for primary outcome

January 26, 2024

Completed
10 months until next milestone

Study Completion

Last participant's last visit for all outcomes

December 1, 2024

Completed
Last Updated

May 22, 2023

Status Verified

May 1, 2023

Enrollment Period

8 months

First QC Date

April 26, 2023

Last Update Submit

May 11, 2023

Conditions

Outcome Measures

Primary Outcomes (1)

  • Active Magnesium Containing Toothpaste (ROCS)

    Active magnesium containing toothpaste can find to be effective in reducing plaque of Turesky-Modified Quinley-Hein-Plaque-Index (TMQHPI) score when compare to Fluoride toothpaste with single-use brushing in children

    1 month

Study Arms (2)

Active Magnesium Containing Toothpaste-ROCS

EXPERIMENTAL

The participants will ask not to eat for 4 hours and not to brush for 24 hours in advance of the test.In the first stage, the preliminary plaque in the children will record by the first researcher using plaque dye.After plaque disclosing the researcher brush children's teeth with ROCS active magnesium toothpaste for 1 minute with a standard toothbrush then the plaque staining will apply again.Also remaining plaque measurements will made using the Gc D lite Pro curring light on detection mode.Dental plaque on the upper anterior incisors will photograph intra-orally before and after brushing under standardized conditions.

Other: Toothpaste

Fluoride Toothpaste-COLGATE

EXPERIMENTAL

After 2 weeks, the same participants will ask not to eat for 4 hours and not to brush for 24 hours in advance of the retest.Initial, the preliminary plaque in the children will record by the first researcher using plaque dye. After plaque disclosing the researcher brush children's teeth with Colgate fluoride toothpaste for 1 minute with a standard toothbrush then the plaque staining will apply again.Also remaining plaque measurements will made using the Gc D lite Pro curring light on detection mode.Dental plaque on the upper anterior incisors will photograph intra-orally before and after brushing under standardized conditions.

Other: Toothpaste

Interventions

Using two different toothpastes for removal of the dental plaque in children.

Active Magnesium Containing Toothpaste-ROCSFluoride Toothpaste-COLGATE

Eligibility Criteria

Age9 Years - 12 Years
Sexall
Healthy VolunteersYes
Age GroupsChild (0-17)

You may qualify if:

  • Patients aged 9-12 years
  • The presence of caries-free and fully erupted upper anterior incisors that can be scored in the mouth
  • Absence of orthodontic appliances/brackets
  • No physical limitations
  • No previous trauma history
  • It was determined as the absence of soft-hard tissue pathology.

You may not qualify if:

  • Patients not between 9-12 years
  • The presence of decay and not fully erupted upper anterior incisors that can be scored in the mouth
  • Presence of orthodontic appliances/brackets
  • Physical limitations
  • Previous trauma history
  • It was determined as the presence of soft-hard tissue pathology.

Contact the study team to confirm eligibility.

Sponsors & Collaborators

MeSH Terms

Conditions

Dental Plaque

Interventions

Toothpastes

Condition Hierarchy (Ancestors)

Dental DepositsTooth DiseasesStomatognathic Diseases

Intervention Hierarchy (Ancestors)

DentifricesBiomedical and Dental MaterialsManufactured MaterialsTechnology, Industry, and Agriculture

Central Study Contacts

Betul Kargul, Prof.Dr.

CONTACT

Nur Kodaman Dokumacigil, DDS

CONTACT

Study Design

Study Type
interventional
Phase
not applicable
Allocation
RANDOMIZED
Masking
NONE
Purpose
PREVENTION
Intervention Model
CROSSOVER
Sponsor Type
OTHER
Responsible Party
PRINCIPAL INVESTIGATOR
PI Title
Professor

Study Record Dates

First Submitted

April 26, 2023

First Posted

May 22, 2023

Study Start

May 26, 2023

Primary Completion

January 26, 2024

Study Completion

December 1, 2024

Last Updated

May 22, 2023

Record last verified: 2023-05

Data Sharing

IPD Sharing
Will not share