Screening for Risk Factors of Prediabetes Among Adult Patients at Sohag University Hospital
1 other identifier
observational
200
1 country
1
Brief Summary
- Prediabetes is an intermediate state of hyperglycemia with glycemic parameters above normal but below the diabetes threshold..
- during the average 3 years of follow-up Prediabetes is diagnosed based on laboratory tests: fasting plasma glucose level (100-125 mg/dl) ;HbA1c, (5.7-6.4%) or plasma glucose level after an oral glucose tolerance test ( 140-199 mg/dl).
- Reports estimate that more than 470 million people will have prediabetes by 2030.
- According to an expert panel of the American Diabetes Association, up to 70% of individuals with prediabetes will eventually develop diabetes.
- Observational evidence suggests as association between prediabetes and complications of diabetes such early nephropathy(10%) , small fiber neuropathy(18-25 %), early retinopathy (8-12%) and risk of macrovascular disease (52%) .
- Screening for prediabetes is designed to save lives or enhance an individual's quality of life by early detection so that screening will minimize the risk of developing diabetes or its complications .
Trial Health
Trial Health Score
Automated assessment based on enrollment pace, timeline, and geographic reach
participants targeted
Target at P75+ for all trials
Started Apr 2023
Shorter than P25 for all trials
1 active site
Health score is calculated from publicly available data and should be used for screening purposes only.
Trial Relationships
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Study Timeline
Key milestones and dates
Study Start
First participant enrolled
April 15, 2023
CompletedFirst Submitted
Initial submission to the registry
April 19, 2023
CompletedFirst Posted
Study publicly available on registry
May 18, 2023
CompletedPrimary Completion
Last participant's last visit for primary outcome
December 1, 2023
CompletedStudy Completion
Last participant's last visit for all outcomes
December 1, 2023
CompletedMay 18, 2023
May 1, 2023
8 months
April 19, 2023
May 8, 2023
Conditions
Outcome Measures
Primary Outcomes (1)
comparison between the measurement of HbA1c in normal non prediabetics and prediabetics at Sohag university hospital .
analysis of HbA1c measurements and compare the results in both groups
6 months
Study Arms (2)
case group
prediabetic
control group
non prediabetic
Interventions
HbA1c will be measured for all patients to minimize the risk of developing diabetes or its complications .
lipid profile will be measured for all patients to minimize the risk of developing diabetes or its complications .
CBC will be measured for all patients to minimize the risk of developing diabetes or its complications
Alb/cr will be measured for all patients to minimize the risk of developing diabetes or its complications
serum creatinine will be measured for all patients to minimize the risk of developing diabetes or its complications
CRP will be measured for all patients to minimize the risk of developing diabetes or its complications
urine analysis will be measured for all patients to minimize the risk of developing diabetes or its complications
ECG will be done for all patients to minimize the risk of developing diabetes or its complications
fundus examination will be done for all patients to minimize the risk of developing diabetes or its complications
Eligibility Criteria
All patients admitted to Sohag University hospital at period of admission 18 years or older wihe exclusion of patients known to be diabetics , pregnants , chronic depleting diseases patients , those who were taking drugs known to influence blood glucose levels e.g. metformin, thiazolidinedione and steroids.
You may qualify if:
- Adult patient above 18 years old .
You may not qualify if:
- all patients known to be diabetics .
- pregnancy .
- chronic depleting diseases,
- Those who were taking drugs known to influence blood glucose levels e.g. metformin, thiazolidinedione and steroids.
Contact the study team to confirm eligibility.
Sponsors & Collaborators
- Sohag Universitylead
Study Sites (1)
Sohag university hospital
Sohag, Egypt
Related Publications (3)
Tabak AG, Herder C, Rathmann W, Brunner EJ, Kivimaki M. Prediabetes: a high-risk state for diabetes development. Lancet. 2012 Jun 16;379(9833):2279-90. doi: 10.1016/S0140-6736(12)60283-9. Epub 2012 Jun 9.
PMID: 22683128BACKGROUNDBeulens J, Rutters F, Ryden L, Schnell O, Mellbin L, Hart HE, Vos RC. Risk and management of pre-diabetes. Eur J Prev Cardiol. 2019 Dec;26(2_suppl):47-54. doi: 10.1177/2047487319880041.
PMID: 31766914BACKGROUNDVas PRJ, Alberti KG, Edmonds ME. Prediabetes: moving away from a glucocentric definition. Lancet Diabetes Endocrinol. 2017 Nov;5(11):848-849. doi: 10.1016/S2213-8587(17)30234-6. Epub 2017 Aug 3. No abstract available.
PMID: 28781065RESULT
MeSH Terms
Conditions
Interventions
Condition Hierarchy (Ancestors)
Intervention Hierarchy (Ancestors)
Central Study Contacts
Study Design
- Study Type
- observational
- Observational Model
- CASE CONTROL
- Time Perspective
- PROSPECTIVE
- Target Duration
- 1 Day
- Sponsor Type
- OTHER
- Responsible Party
- PRINCIPAL INVESTIGATOR
- PI Title
- internal medicine resident at faculty of medicine Sohag university
Study Record Dates
First Submitted
April 19, 2023
First Posted
May 18, 2023
Study Start
April 15, 2023
Primary Completion
December 1, 2023
Study Completion
December 1, 2023
Last Updated
May 18, 2023
Record last verified: 2023-05