Prediction of Vesicouterine Adhesions by Transvaginal Sonographic Sliding Sign Technique: a Validation Study

NCT05862155 | Completed

• 1 other identifier: Sliding Bladder
• Study Type: observational
• Target: 132
• Locations: 1 country
• Sites: 1

Brief Summary

The aim of this study is to evaluate the predictive value of the real-time dynamic TVS sliding sign for vesicouterine pouch adhesions in women and to test the inter- and intraobserver agreement of this new technique.

Conditions

Adhesions Pelvic; Adhesion; Uterus; Adhesion; Bladder

Keywords

adhesion; vesicouterine; bladder; uterus; real-time dynamic; transvaginal sonography; sliding sign; ultrasound

Outcome Measures

Primary Outcomes (1)

• Transvaginal sonographic sliding sign

  Real-time dynamic transvaginal sonographic sliding sign (positive or negative sign)

  Preoperative

Secondary Outcomes (1)

• Adhesion score

  Intraoperative recording of laparoscopic footage with postoperative assessment of the adhesion score based on this video within 2 years

Eligibility Criteria

• Age: 18 Years+
• Sex: female
• Healthy Volunteers: Yes
• Age Groups: Adult (18-64), Older Adult (65+)
• Sampling Method: Probability Sample

Study Population

Women undergoing laparoscopic gynecological surgery at the Amsterdam UMC, location AMC who signed informed consent for the Status Studies, Niche Cohort or QUESTA study.

You may qualify if:

• Women \> 18 years old
• Laparoscopic abdominopelvic surgery with available video footage in Clinical Assistent
• Recorded real-time dynamic transvaginal ultrasound with the sliding sign technique
• Signed informed consent

You may not qualify if:

• Insufficient quality of the ultrasound
• Unclear laparoscopic videoclip to determine the presence of adhesions

Sponsors & Collaborators

• Amsterdam UMC, location VUmc: lead

Study Sites (1)

Amsterdam UMC, location AMC

Amsterdam, North Holland, 1105 AZ, Netherlands

Location

Related Publications (4)

• Baron J, Tirosh D, Mastrolia SA, Ben-Haroush Y, Schwartz S, Kerner Y, Hershkovitz R. Sliding sign in third-trimester sonographic evaluation of intra-abdominal adhesions in women undergoing repeat Cesarean section: a novel technique. Ultrasound Obstet Gynecol. 2018 Nov;52(5):662-665. doi: 10.1002/uog.19057.

  PMID: 29575202 BACKGROUND

• Hudelist G, Oberwinkler KH, Singer CF, Tuttlies F, Rauter G, Ritter O, Keckstein J. Combination of transvaginal sonography and clinical examination for preoperative diagnosis of pelvic endometriosis. Hum Reprod. 2009 May;24(5):1018-24. doi: 10.1093/humrep/dep013. Epub 2009 Feb 6.

  PMID: 19202143 BACKGROUND

• Tulandi T, Lyell DJ. Classification of intra-abdominal adhesions after cesarean delivery. Gynecol Surg. 2013;10(1):25-9.

  BACKGROUND

• Min N, van Keizerswaard J, Visser RH, Burger NB, Rake JWT, Aarts JWM, Van den Bosch T, Leonardi M, Huirne JAF, de Leeuw RA. Prediction of vesicouterine adhesions by transvaginal sonographic sliding sign technique: validation study. Ultrasound Obstet Gynecol. 2025 Jan;65(1):114-121. doi: 10.1002/uog.29128. Epub 2024 Nov 25.

  PMID: 39587459 DERIVED

MeSH Terms

Conditions

Gynatresia; Tissue Adhesions

Condition Hierarchy (Ancestors)

Genital Diseases, Female; Female Urogenital Diseases; Female Urogenital Diseases and Pregnancy Complications; Urogenital Diseases; Genital Diseases; Cicatrix; Fibrosis; Pathologic Processes; Pathological Conditions, Signs and Symptoms

Study Officials

• Judith Huirne, Prof. Dr.

  Amsterdam UMC, location VUmc

  PRINCIPAL INVESTIGATOR

Study Design

• Study Type: observational
• Observational Model: COHORT
• Time Perspective: PROSPECTIVE
• Sponsor Type: OTHER
• Responsible Party: PRINCIPAL INVESTIGATOR
• PI Title: Prof. Dr. J.A.F. Huirne

Study Record Dates

• First Submitted: May 5, 2023
• First Posted: May 17, 2023
• Study Start: January 27, 2020
• Primary Completion: January 19, 2022
• Study Completion: February 13, 2023
• Last Updated: May 17, 2023

Record last verified: 2023-05

Locations

NL (1)