Long-Term Follow-Up in Patients With Acute Myocardial Infarction Cohort

NCT05862103 | Recruiting

• 1 other identifier: KY2022-266
• Study Type: observational
• Target: 15,000
• Locations: 1 country
• Sites: 18

Brief Summary

AMI Survivors who participated in the project "Construction and key technology research of the whole myocardial protection system for acute myocardial infarction" (project number 2016YFC1301100) and completed the 1-year visit were followed up by telephone at 3 years (within the corresponding follow-up time window) and 5 years after discharge to acquire the patients' medication, health status, and major adverse cardiovascular and cerebrovascular events, including death, heart failure, rehospitalization, re-myocardial infarction, revascularization, stroke, malignant arrhythmia, and bleeding events.

Conditions

Acute Myocardial Infarction; Adverse Event

Keywords

Acute myocardial infarction; Major adverse cardiac and cerebrovascular event; Optimized treatment

Outcome Measures

Primary Outcomes (1)

• Incidence of MACCE

  the incidence of MACCE (death, heart failure, rehospitalization, re-myocardial infarction, re-myocardial revascularization, stroke, malignant arrhythmia, bleeding events, etc.) in AMI patients

  5 years after discharge

Secondary Outcomes (4)

• Differences of MACCE between the optimized group and the non-optimized group

  5 years after discharge

• Differences of the MACCE between OCT-guided group and the coronary angiography -guided group

  5 years after discharge

• Differences of MACCE between defer PCI group and direct PCI group

  3 and 5 years after discharge

• Differences of the MACCE incidence between cardiac rehabilitation quality improvement group and non-cardiac rehabilitation group

  5 years after discharge

Study Arms (2)

optimized group

the patients received at least one optimized treatment

Other: Treatment Strategies

un-optimized group

the patients didn't receive optimized treatment

Interventions

Treatment Strategies OTHER

AMI emergency treatment process, pre-reperfusion medication, reperfusion strategy selection, and early cardiac rehabilitation after reperfusion

optimized group

Eligibility Criteria

• Age: 18 Years+
• Sex: all
• Healthy Volunteers: No
• Age Groups: Adult (18-64), Older Adult (65+)
• Sampling Method: Non-Probability Sample

Study Population

AMI survivors who participated in the project "Construction and key technology research on the whole myocardial protection system for acute myocardial infarction" and completed 1-year visit

You may qualify if:

• AMI survivors who participated in the project "Construction and key technology research of the whole myocardial protection system for acute myocardial infarction" and completed the 1-year visit.
• Telephone to obtain informed consent from the subjects/family members of the subjects.

You may not qualify if:

• Not available

Sponsors & Collaborators

• Yu Bo: lead

Study Sites (18)

Beijing An Zhen Hospital, Capital Medical University

Beijing, Beijing Municipality, 100029, China

RECRUITING

Beijing Chao-Yang Hospital, Capital Medical University

Beijing, Beijing Municipality, China

RECRUITING

Peking University First Hospital

Beijing, Beijing Municipality, China

NOT YET RECRUITING

Guangdong general hospital

Guangzhou, Guangdong, China

RECRUITING

The first affiliated hospital of Guangxi medical university

Nanning, Guangxi, 530021, China

RECRUITING

Second hospital of hebei medical university

Shijiazhuang, Hebei, China

RECRUITING

Daqing Oil Field Hospital

Daqing, Heilongjiang, China

RECRUITING

The First Affiliated Hospital of Zhengzhou University

Zhengzhou, Henan, China

RECRUITING

Zhongda Hospital Southeast University

Nanjing, Jiangsu, 210009, China

RECRUITING

The Second Affiliated Hospital of Nanchang University

Nanchang, Jiangxi, 330006, China

RECRUITING

The Second Hospital of Jilin University

Changchun, Jilin, 150056, China

RECRUITING

The econd Affiliated Hospital of Dalian Medical University

Dalian, Liaoning, China

RECRUITING

General Hospital of Northern Theater Command of the Chinese People's Liberation Army

Shenyang, Liaoning, China

RECRUITING

Xijing Hospital of Air Force Military Medical University

Xi’an, Shanxi, China

RECRUITING

Xinqiao Hospital Army Medical University

Chongqing, Sichuan, 400000, China

RECRUITING

The General Hospital of Tianjin Medical University

Tianjin, Tianjin Municipality, China

RECRUITING

Tianjin Chest Hospital

Tianjin, Tianjin Municipality, China

RECRUITING

First Affiliated Hospital of Xinjiang Medical University

Ürümqi, Xinjiang, China

RECRUITING

Study Officials

• Bo Yu

  The Second Affiliated Hospital of Harbin Medical University

  STUDY CHAIR

Central Study Contacts

Xiling Zhang, MD

CONTACT

+86 13804608748; xlzhangdr@163.com

Study Design

• Study Type: observational
• Observational Model: COHORT
• Time Perspective: PROSPECTIVE
• Sponsor Type: OTHER
• Responsible Party: SPONSOR INVESTIGATOR
• PI Title: Director

Study Record Dates

• First Submitted: May 8, 2023
• First Posted: May 17, 2023
• Study Start: December 21, 2022
• Primary Completion: August 30, 2025
• Study Completion (Estimated): December 30, 2026
• Last Updated: September 3, 2025

Record last verified: 2025-08

Data Sharing

• IPD Sharing: Will not share

Locations

CN (18)