Trials Sponsors Conditions Drugs Pricing

Conditions

Acne Atrophica

Keywords

Acne Scar, Dezocine, Pain Relief, Fractional CO2 Laser

Outcome Measures

Primary Outcomes (4)

Visual Analog Score for Pain
0 was classified as painless and 10 was classified as unbearable pain. Marks were made on the corresponding parts of the ruler and scores were scored according to the degree of patient's feeling
24 hours
Hemodynamic parameters
diastolic blood pressure (DBP), systolic blood pressure (SBP)
24 hours
Heart rate (HR)
Hemodynamic parameters
24 hours
oxygen saturation (SpO2)
Hemodynamic parameters
24 hours

Secondary Outcomes (1)

Occurrence of Adverse Reactions
24 hours

Study Arms (3)

control group

PLACEBO COMPARATOR

The patients were divided into 3 groups based on different dosages of Dezocine injection, with 35 patients in each group: Group 1: Dezocine low-dose group, Group 2: Dezocine high-dose group; Group 3: Blank control group (normal saline).

Device: Fractional CO2 laser

Dezocine low dose group

EXPERIMENTAL

Device: Fractional CO2 laserDrug: Dezocine

Dezocine high dose group

EXPERIMENTAL

Interventions

Fractional CO2 laserDevice

All patients were given oral administration of 0.5mg paronosetron hydrochloride and lidocaine cream 1 hour before surgery. After cleaning and disinfection, fractional CO2 laser treatment was given. Among them, the fractional CO2 laser laser (American Medical Laser company) selected relatively constant energy parameters in the treatment

Also known as: paronosetron hydrochloride and lidocaine cream

Dezocine high dose groupDezocine low dose groupcontrol group

DezocineDrug

Eligibility Criteria

Age18 Years - 60 Years

Sexall

Healthy VolunteersNo

Age GroupsAdult (18-64)

You may qualify if:

Age: 18-60 years old, regardless of gender;
Clinical diagnosis of atrophic acne scars;

Sponsors & Collaborators

Xijing Hospital
Otherlead

Study Sites (1)

Dermatology Derpartment of Xijing Hospital

Xi'an, Shaanxi, 710032, China

RECRUITING

Gang Wang, profCONTACT+8684775401 xjwgang@fmmu.edu.cn

MeSH Terms

Interventions

dezocine

Study Officials

Gang Wang, Prof
Dermatology Derpartment of Xijing Hospital
PRINCIPAL INVESTIGATOR

Central Study Contacts

Chen Yu, MD

CONTACT

13571991903 ycyc_2005@163.com

Study Design

Study Type: interventional
Phase: phase 4
Allocation: RANDOMIZED
Masking: QUADRUPLE
Who Masked: PARTICIPANT, CARE PROVIDER, INVESTIGATOR, OUTCOMES ASSESSOR
Purpose: SUPPORTIVE CARE
Intervention Model: PARALLEL
Sponsor Type: OTHER
Responsible Party: SPONSOR

Study Record Dates

First Submitted

April 17, 2023

First Posted

May 16, 2023

Study Start

February 11, 2023

Actual (reported)

Primary Completion

December 30, 2023

Estimated (date passed)

The Efficacy and Safety of Dezocine Pretreatment for Pain Relief in Acne Scar Treatment of Fractional CO2 Laser

Brief Summary

Registry Overview

Trial Relationships

Study Timeline

Study Start

First Submitted

First Posted

Primary Completion

Study Completion

Conditions

Keywords

Outcome Measures

Primary Outcomes (4)

Secondary Outcomes (1)

Study Arms (3)

control group

Dezocine low dose group

Dezocine high dose group

Interventions

Eligibility Criteria

You may qualify if:

Sponsors & Collaborators

Study Sites (1)

MeSH Terms

Interventions

Study Officials

Central Study Contacts

Study Design

Study Record Dates

You may not qualify if:

Data Sharing

Source record

Locations

Brief Summary

Registry Overview

Trial Relationships

Related Scientific Literature

Study Timeline

Study Start

First Submitted

First Posted

Primary Completion

Study Completion

Conditions

Keywords

Outcome Measures

Primary Outcomes (4)

Secondary Outcomes (1)

Study Arms (3)

control group

Dezocine low dose group

Dezocine high dose group

Interventions

Eligibility Criteria

You may qualify if:

Sponsors & Collaborators

Study Sites (1)

MeSH Terms

Interventions

Study Officials

Central Study Contacts

Study Design

Study Record Dates

You may not qualify if:

Data Sharing

Source record

Locations