NCT05849935

Brief Summary

This is a monocentric, prospective, biomarker-result-blinded observational study evaluating immunoassay measurements of pancreatic stone protein (PSP) performed on Abionic's abioSCOPE device with the PSP assay on generally healthy adults representative of the US population.

Trial Health

87
On Track

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Enrollment
61

participants targeted

Target at P25-P50 for all trials

Timeline
Completed

Started Jul 2023

Geographic Reach
1 country

1 active site

Status
completed

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

Click on a node to explore related trials.

Study Timeline

Key milestones and dates

First Submitted

Initial submission to the registry

April 28, 2023

Completed
11 days until next milestone

First Posted

Study publicly available on registry

May 9, 2023

Completed
2 months until next milestone

Study Start

First participant enrolled

July 17, 2023

Completed
14 days until next milestone

Primary Completion

Last participant's last visit for primary outcome

July 31, 2023

Completed
Same day until next milestone

Study Completion

Last participant's last visit for all outcomes

July 31, 2023

Completed
Last Updated

August 14, 2023

Status Verified

July 1, 2023

Enrollment Period

14 days

First QC Date

April 28, 2023

Last Update Submit

August 10, 2023

Conditions

Outcome Measures

Primary Outcomes (1)

  • To determine the reference range intervals of PSP values measured using abioSCOPE device with the PSP assay in a generally healthy population representative of the US population.

    through study completion, an average of 2 months

Interventions

abioSCOPEDIAGNOSTIC_TEST

The abioSCOPE device with the PSP assay is intended to be indicated for ICU admitted patients at risk of developing sepsis. Results of abioSCOPE PSP assay may aid to identify sepsis in critically ill patients, together with all other clinical assessment and laboratory findings.

Eligibility Criteria

Age18 Years+
Sexall
Healthy VolunteersYes
Age GroupsAdult (18-64), Older Adult (65+)
Sampling MethodNon-Probability Sample
Study Population

Adult healthy population

You may qualify if:

  • Male or female, aged ≥ 18 years.
  • Apparently healthy as determined by a subject questionnaire.

You may not qualify if:

  • Current diagnosis, or history, of any underlying major medical condition determined by the investigator, including but not limited to
  • Renal disease
  • Stoke
  • Liver disease
  • Pancreatic disease (including diabetes)
  • HIV AIDS
  • Receiving antibiotic therapy
  • Suspected infection
  • Immunosuppression
  • Underwent procedures related to sepsis, or diagnosed with sepsis, within the last 12 months.
  • Current diagnosis of uncontrolled diabetes.
  • Diagnosis of bacterial, fungal, or malaria infection within the last 3 months that required antimicrobial treatment.
  • Experienced severe trauma, surgery, cardiac arrest, or severe burn within the previous 3 months requiring medical care.
  • Diagnosis and/or treatment of cancer within the last 12 months.
  • Received immunosuppressive therapy.
  • +3 more criteria

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Study Sites (1)

Sundance Clinical

St Louis, Missouri, 63141, United States

Location

MeSH Terms

Conditions

Sepsis

Condition Hierarchy (Ancestors)

InfectionsSystemic Inflammatory Response SyndromeInflammationPathologic ProcessesPathological Conditions, Signs and Symptoms

Study Design

Study Type
observational
Observational Model
COHORT
Time Perspective
PROSPECTIVE
Sponsor Type
INDUSTRY
Responsible Party
SPONSOR

Study Record Dates

First Submitted

April 28, 2023

First Posted

May 9, 2023

Study Start

July 17, 2023

Primary Completion

July 31, 2023

Study Completion

July 31, 2023

Last Updated

August 14, 2023

Record last verified: 2023-07

Data Sharing

IPD Sharing
Will not share

Locations