Diagnostic Performance of Dogs for the Olfactory Detection of COVID-19
CYNOCOV
Pilot Study for the Experimental Validation of the Intrinsic Diagnostic Performance Among the First Dod Team for the Canine Olfactory Detection of COVID-19 on Sweat Samples From Persons Tested by PCR SARS-CoV-2.
1 other identifier
observational
1,548
1 country
6
Brief Summary
Considering the favorable preliminary data of few european diagnostic studies on dog detection, we develop in 2021 a pilot study in response to the plan of CHU Bordeaux and Nouvelle Aquitaine French region for an expanded, reliable and alternative rapid dog olfactory detection of COVID during pandemic period. Our hypothesis is that validated olfactory detection on sweat or face mask collection by dogs would increase the acceptability and propensity to be tested in different population groups, given the non-invasive nature of sweat and face mask; compared to the unpleasant aspect of nasal swabs for PCR or rapid antigenic tests. To reach this objective, we recruited a dog team to be trained and assessed (all-volunteers masters and dogs) and we will recruit participants with positive and negative PCR test. The diagnostic performance of canine olfactory detection of COVID-19 on sweat and face collection will be compared to the nasal SARS-Cov-2 PCR test of the participants.
Trial Health
Trial Health Score
Automated assessment based on enrollment pace, timeline, and geographic reach
participants targeted
Target at P75+ for all trials
Started May 2021
6 active sites
Health score is calculated from publicly available data and should be used for screening purposes only.
Trial Relationships
Click on a node to explore related trials.
Study Timeline
Key milestones and dates
Study Start
First participant enrolled
May 27, 2021
CompletedPrimary Completion
Last participant's last visit for primary outcome
May 28, 2022
CompletedStudy Completion
Last participant's last visit for all outcomes
June 28, 2022
CompletedFirst Submitted
Initial submission to the registry
May 4, 2023
CompletedFirst Posted
Study publicly available on registry
May 6, 2023
CompletedMay 31, 2023
April 1, 2023
1 year
May 4, 2023
May 26, 2023
Conditions
Keywords
Outcome Measures
Primary Outcomes (1)
Experimentally validate the intrinsic diagnostic performance of dogs for the olfactory detection of COVID-19
Combined measurement of a Sensitivity \> 80% and a specificity \> 60% of each dog and of all the dogs eligible for the week of evaluation of the canine olfactory detection of COVID-19; compared to the SARS-Cov-2 PCR test (gold standard)
day 1
Secondary Outcomes (4)
Experimentally validate the intrinsic performance
day 1
Experimentally validate the intrinsic performance
day 1
Canine olfactory detection on mask
day 1
Evaluation of the intrinsic and discriminative diagnostic performance of dogs for the olfactory detection of COVID-19 on sweat samples and/or used respiratory masks
day 1
Interventions
Collection of sweat samples and used face mask will take approximately 15 minutes before or after collection for the SARS-Cov PCR test
Eligibility Criteria
people screened by SARS-CoV2 PCR
You may not qualify if:
- Confirmed or suspected long-haul symptoms of COVID-19 Patient subject to a judicial protection measure Person opposing the study (child or parent if minor) OR not understanding French
Contact the study team to confirm eligibility.
Sponsors & Collaborators
Study Sites (6)
University Hospital Bordeaux, France
Bordeaux, 33000, France
Hospital Dax
Dax, 40107, France
Hospital Libourne
Libourne, 33505, France
University Hospital Limoges, France
Limoges, 87042, France
Hospital Périgueux
Périgueux, 24019, France
Universtity Hospital Poitiers
Poitiers, 86021, France
Biospecimen
Collection of sweat samples and face mask
MeSH Terms
Conditions
Condition Hierarchy (Ancestors)
Study Officials
- PRINCIPAL INVESTIGATOR
Thierry PISTONE, Dr
University Hospital Bordeaux, France
Study Design
- Study Type
- observational
- Observational Model
- CASE CONTROL
- Time Perspective
- PROSPECTIVE
- Sponsor Type
- OTHER
- Responsible Party
- SPONSOR
Study Record Dates
First Submitted
May 4, 2023
First Posted
May 6, 2023
Study Start
May 27, 2021
Primary Completion
May 28, 2022
Study Completion
June 28, 2022
Last Updated
May 31, 2023
Record last verified: 2023-04