The Soft Tissue Mobilization Techniques on PMS

NCT05836454 | Completed

• 1 other identifier: PMSBloodFlow
• Study Type: interventional
• Target: 94
• Locations: 1 country
• Sites: 1

Brief Summary

The aim of this study is investigate the effects of progressive relaxation and myofascial release technique on blood flow velocity, pain, premenstrual symptoms and quality of life in premenstrual syndrome patients. There are tree groups in the study. These groups are; progressive muscle relaxation group, myofascial relaxation technique and control group. Evaluations will be made by another physical therapist who is blinded to the groups. Participants will be evaluated within the first 3 days of their menstrual cycle. Baseline assessment and post- treatment assessment will be done. Follow-up evaluation will be done on the fifth cycle, two cycles after the post-treatment evaluation.

Conditions

Premenstrual Syndrome; Premenstrual Pain; Chronic Pelvic Pain

Keywords

myofascial releasing technique; progressive relaxation technique; blood flow velocity

Outcome Measures

Primary Outcomes (2)

• Change from Baseline Blood Flow Rate at Two Menstrual Cycle

  Blood flow rate will be evaluated with the portable vascular doppler. Measurements will be made from the right or left common iliac artery, branches of the abdominal aorta, and the ipsilateral femoral artery. After the ultrasound gel is applied to the measurement area, the probe will be placed at an angle of 30° and the measurement will be taken.

  Baseline and 8 weeks

• Follow- up Evaluation Blood Flow Rate

  Blood flow rate will be evaluated with the portable vascular doppler. Measurements will be made from the right or left common iliac artery, branches of the abdominal aorta, and the ipsilateral femoral artery. After the ultrasound gel is applied to the measurement area, the probe will be placed at an angle of 30° and the measurement will be taken.

  8 weeks through study completion

Secondary Outcomes (8)

• Change from Baseline Pain Severity at Two Menstrual Cycle

  Baseline and 8 weeks

• Follow-up Evaluation Pain Severity at Two Menstrual Cycle

  8 weeks through study completion

• Change from Baseline Pain Threshold at Two Menstrual Cycle

  Baseline and 8 weeks

• Follow-up Evaluation Pain Threshold

  8 weeks through study completion

• Change from Baseline Premenstrual Syndrome at Two Menstrual Cycle

  Baseline and 8 weeks

Study Arms (3)

Progressive Muscle Relaxation Group:

EXPERIMENTAL

Progressive Muscle Relaxation technique will be applied to this group. Technique will be applied 3 days a week for 2 menstrual cycles.

Other: Progressive Muscle Relaxation Group:

Myofascial Release Technique Group

EXPERIMENTAL

Myofascial Release Technique will be applied to this group. Technique will be applied 3 days a week for 2 menstrual cycles.

Other: Myofascial Release Technique Group

Control Group

NO INTERVENTION

The control group will be asked to continue their normal lives.

Interventions

Progressive Muscle Relaxation Group: OTHER

Progressive muscle relaxation is a relaxation technique that involves regular and sequential contraction and relaxation of muscles until the whole body is relaxed.

Progressive Muscle Relaxation Group:

Myofascial Release Technique Group OTHER

It is a physiotherapy technique based on soft tissue mobilization. All enveloping fascia sale prices are positive for mobility, a user used for adhesions and pain.

Myofascial Release Technique Group

Eligibility Criteria

• Age: 18 Years - 30 Years
• Sex: female
• Healthy Volunteers: No
• Age Groups: Adult (18-64)

You may qualify if:

• Pain score of 4 cm or more according to the Visual Analogue Scale.
• Having a regular menstrual cycle for 12 months (24-35 days).
• According to the International Physical Activity Questionnaire-Short Form (IPAQ-SF), the weekly Metabolic Equivalent of Task (MET) value is below 600 MET-min/week.

You may not qualify if:

• Those who have undergone surgery in the last 6 months,
• Those who use cigarettes and alcohol,
• Those who are pregnant,
• Those with urinary, genital, gastrointestinal disorders,
• Those who have had hysterectomy surgery will be excluded.

Sponsors & Collaborators

• Eastern Mediterranean University: lead

Study Sites (1)

Eastern Mediterranean University

Famagusta, Cyprus

Location

MeSH Terms

Conditions

Premenstrual Syndrome

Condition Hierarchy (Ancestors)

Menstruation Disturbances; Pathologic Processes; Pathological Conditions, Signs and Symptoms

Study Officials

• Çisel Demiralp, Msc

  Eastern Meditteranean Univeristy

  PRINCIPAL INVESTIGATOR

Study Design

• Study Type: interventional
• Phase: not applicable
• Allocation: RANDOMIZED
• Masking: SINGLE
• Who Masked: OUTCOMES ASSESSOR
• Masking Details: Evaluations will be made by another physical therapist who is blinded to the groups.
• Purpose: TREATMENT
• Intervention Model: PARALLEL
• Sponsor Type: OTHER
• Responsible Party: SPONSOR

Model Details: Single Blind Randomized Controlled Study

Study Record Dates

• First Submitted: March 14, 2023
• First Posted: May 1, 2023
• Study Start: September 1, 2022
• Primary Completion: June 30, 2025
• Study Completion: June 30, 2025
• Last Updated: July 16, 2025

Record last verified: 2025-05

Locations

CY (1)