The ARRC III Trial of Advanced Recovery Room Care (ARRC).

NCT05836285 | Recruiting DMC

• 1 other identifier: 17557
• Study Type: observational
• Target: 3,000
• Locations: 1 country
• Sites: 1

Brief Summary

A postoperative high-acuity model of care (ARRC) has been shown, in a prospective cohort study of approximately 850 patients, to produce a marked improvement in patient and hospital outcomes, and hospital costs, in medium risk patients (Ludbrook G et al., JAMA Surgery 2023). The goal of this observational study is to examine the outcomes after non-cardiac surgery of a larger group of medium risk patients receiving different forms of care -ARRC and usual ward care. The main questions it aims to answer are: what are the outcomes for patients and hospital after the different forms of care, who receives benefit from high acuity care, what underlies the improved outcomes seen with high acuity care.

Conditions

Post-Surgical Complication; Economic Problems

Keywords

postoperative complications; safety; health economics; quality of recovery after surgery; surgery; anaesthesia

Outcome Measures

Primary Outcomes (1)

• Days at Home after surgery

  number of days spent at usual place of residence within 90 days after surgery

  90 days after surgery

Secondary Outcomes (3)

• in-hospital complications

  out to 10 days after surgery

• mortality

  12 months after surgery

• cost-effectiveness

  90 days after surgery

Study Arms (1)

Medium risk patients undergoing surgery

Patients undergoing surgery designated as medium risk using NSQIP risk scores

Other: ARRC; Other: Usual Care

Interventions

ARRC OTHER

Eligible for ARRC and managed in ARRC unit

Medium risk patients undergoing surgery

Usual Care OTHER

Eligible for ARRC but managed elsewhere as no ARRC bed available

Medium risk patients undergoing surgery

Eligibility Criteria

• Age: 18 Years+
• Sex: all
• Healthy Volunteers: No
• Age Groups: Adult (18-64), Older Adult (65+)
• Sampling Method: Non-Probability Sample

Study Population

Patients undergoing surgery at Royal Adelaide Hospital

You may qualify if:

• Scheduled for elective or unplanned surgery
• Scheduled to stay in hospital at least one night after surgery
• day mortality of 0.5% to 8% by the US National Safety and Quality Improvement Program risk score (NSQIP)

You may not qualify if:

• Undergoing cardiac surgery
• Scheduled for postoperative Intensive Care Unit management

Sponsors & Collaborators

• University of Adelaide: lead
• Royal Adelaide Hospital: collaborator

Study Sites (1)

Royal Adelaide Hospital

Adelaide, South Australia, 5000, Australia

RECRUITING

Related Publications (1)

• Ludbrook G, Lloyd C, Story D, Maddern G, Riedel B, Richardson I, Scott D, Louise J, Edwards S. The effect of advanced recovery room care on postoperative outcomes in moderate-risk surgical patients: a multicentre feasibility study. Anaesthesia. 2021 Apr;76(4):480-488. doi: 10.1111/anae.15260. Epub 2020 Oct 7.

  PMID: 33027534 RESULT

MeSH Terms

Conditions

Postoperative Complications

Condition Hierarchy (Ancestors)

Pathologic Processes; Pathological Conditions, Signs and Symptoms

Study Officials

• Guy Ludbrook, MBBS PhD

  Professor of Anaesthesia

  PRINCIPAL INVESTIGATOR

Central Study Contacts

Guy L Ludbrook, MBBS PhD

CONTACT

+61 413817901; guy.ludbrook@sa.gov.au

Kathy Heyman, RN

CONTACT

+61 8 7074 5044; kathy.heyman2@sa.gov.au

Study Design

• Study Type: observational
• Observational Model: COHORT
• Time Perspective: PROSPECTIVE
• Target Duration: 18 Months
• Sponsor Type: OTHER
• Responsible Party: PRINCIPAL INVESTIGATOR
• PI Title: Professor of Anaesthesia

Study Record Dates

• First Submitted: April 18, 2023
• First Posted: May 1, 2023
• Study Start: April 18, 2023
• Primary Completion: July 18, 2025
• Study Completion: December 1, 2025
• Last Updated: August 14, 2024

Record last verified: 2024-08

Locations

AU (1)