Postoperative Analgesic Efficacy of Trans Abdominis Plane Block
1 other identifier
interventional
60
1 country
1
Brief Summary
Transverse abdominis plane (TAP) block is an effective method to manage postoperative pain in patients with midline abdominal wall incisions. It is used frequently in many lower abdominal surgeries however its use after caesarean section is still new, and fewer studies are available. We conducted this study to see the analgesic effect of TAP block after caesarean section.
Trial Health
Trial Health Score
Automated assessment based on enrollment pace, timeline, and geographic reach
participants targeted
Target at P25-P50 for not_applicable
Started Jun 2022
Shorter than P25 for not_applicable
1 active site
Health score is calculated from publicly available data and should be used for screening purposes only.
Trial Relationships
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Study Timeline
Key milestones and dates
Study Start
First participant enrolled
June 1, 2022
CompletedPrimary Completion
Last participant's last visit for primary outcome
December 31, 2022
CompletedStudy Completion
Last participant's last visit for all outcomes
December 31, 2022
CompletedFirst Submitted
Initial submission to the registry
April 13, 2023
CompletedFirst Posted
Study publicly available on registry
April 26, 2023
CompletedApril 26, 2023
April 1, 2023
7 months
April 13, 2023
April 25, 2023
Conditions
Keywords
Outcome Measures
Primary Outcomes (1)
Postoperative opioid consumption
within 24hours after surgery
24 hours post cesarean section
Secondary Outcomes (3)
Pain intensity Score
from end of secarean section till 24 post operative hours
Vomiting
Within 24hours after surgery
Duration of First Rescue Analgesia
Within 24hours after surgery
Study Arms (2)
TAP block group
EXPERIMENTALAt the end of the cesarean section, a TAP block will be given by Injecting of 20ml 0.25% Bupivacaine on both sides of the midline using ultrasound-guided subcostal approach
Placebo group
NO INTERVENTIONAt the end of the cesarean section, 20 ml of saline will be injected on both sides of the midline
Interventions
Ultrasound guided infiltration of local anaesthetic bupivacaine via 22G Quincke needle between internal oblique and trans abdominis muscle layers in abdominal wall.
Eligibility Criteria
You may qualify if:
- Elective Caesarean section
- ASA 1-3
- yrs to 45yrs
You may not qualify if:
- Emergency Surgery
- known allergy to local anaesthetic
- severe pre-eclampsia
- placenta accreta
- ASA 4
- Coagulopathy
- Hemodynamically unstable
Contact the study team to confirm eligibility.
Sponsors & Collaborators
Study Sites (1)
Combined Military Hospital
Sargodha, Punjab Province, Pakistan
MeSH Terms
Conditions
Condition Hierarchy (Ancestors)
Study Design
- Study Type
- interventional
- Phase
- not applicable
- Allocation
- RANDOMIZED
- Masking
- NONE
- Purpose
- PREVENTION
- Intervention Model
- PARALLEL
- Sponsor Type
- OTHER
- Responsible Party
- PRINCIPAL INVESTIGATOR
- PI Title
- clinical professor
Study Record Dates
First Submitted
April 13, 2023
First Posted
April 26, 2023
Study Start
June 1, 2022
Primary Completion
December 31, 2022
Study Completion
December 31, 2022
Last Updated
April 26, 2023
Record last verified: 2023-04