NCT05831371

Brief Summary

Etiology and cognitive prognosis in late onset epilepsy differ from young adults epilepsy. At the epilepsy onset, this is crucial to detect potential curative/treatable brain disorders. After classical investigation including morphological brain imaging, EEG, clinical assessment, which added value may have brain FDG PET in the diagnosis and prognosis evaluation?

Trial Health

43
At Risk

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Trial has exceeded expected completion date
Enrollment
87

participants targeted

Target at P50-P75 for all trials

Timeline
Completed

Started May 2023

Shorter than P25 for all trials

Geographic Reach
1 country

1 active site

Status
unknown

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

Click on a node to explore related trials.

Study Timeline

Key milestones and dates

First Submitted

Initial submission to the registry

April 14, 2023

Completed
12 days until next milestone

First Posted

Study publicly available on registry

April 26, 2023

Completed
6 days until next milestone

Study Start

First participant enrolled

May 2, 2023

Completed
3 months until next milestone

Primary Completion

Last participant's last visit for primary outcome

August 2, 2023

Completed
1 month until next milestone

Study Completion

Last participant's last visit for all outcomes

September 2, 2023

Completed
Last Updated

April 26, 2023

Status Verified

April 1, 2023

Enrollment Period

3 months

First QC Date

April 14, 2023

Last Update Submit

April 25, 2023

Conditions

Late Onset EpilepsyAlzheimer Disease

Keywords

FDG PETcognitive prognosis

Outcome Measures

Primary Outcomes (1)

  • diagnostic performances

    sensibility, specificty, accurracy

    2 years after epilepsy onset

Secondary Outcomes (1)

  • cognitive prognosis performances

    2 years after epilepsy onset

Interventions

TEP FDGDIAGNOSTIC_TEST

FDG TEP peformed in clinical routine

Eligibility Criteria

Age60 Years+
Sexall
Healthy VolunteersNo
Age GroupsAdult (18-64), Older Adult (65+)
Sampling MethodNon-Probability Sample
Study Population

non lesional late onset epilepsy

You may qualify if:

  • late onset épilepsy patients without lesion
  • epilepsy followed at the CHRU Nancy france

You may not qualify if:

  • epilepsy explained by cortical lesion
  • severe psychiatric disorders
  • severe addiction (alcool, drugs)
  • no FDG TEP performed
  • no neuropsychological assessement after 2 years epilepsy onset

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Study Sites (1)

CHRU Nancy

Nancy, 54000, France

Location

MeSH Terms

Conditions

Alzheimer Disease

Condition Hierarchy (Ancestors)

DementiaBrain DiseasesCentral Nervous System DiseasesNervous System DiseasesTauopathiesNeurodegenerative DiseasesNeurocognitive DisordersMental Disorders

Study Design

Study Type
observational
Observational Model
COHORT
Time Perspective
RETROSPECTIVE
Sponsor Type
OTHER
Responsible Party
PRINCIPAL INVESTIGATOR
PI Title
Pr

Study Record Dates

First Submitted

April 14, 2023

First Posted

April 26, 2023

Study Start

May 2, 2023

Primary Completion

August 2, 2023

Study Completion

September 2, 2023

Last Updated

April 26, 2023

Record last verified: 2023-04

Data Sharing

IPD Sharing
Will not share

Locations

FR(1)