Characterization of Mentalization Profiles Related to Emotional Regulation Among Teenagers With Behavioral Disorders

NCT05820581 | Recruiting

• 1 other identifier: 2021/646
• Study Type: interventional
• Target: 65
• Locations: 1 country
• Sites: 1

Brief Summary

Behavioral disorders in adolescents are defined by a set of diverse behaviors (such as aggressiveness, agitation, clastic crisis, running away and endangerment) whose common characteristic is the predominance of action/ mentalization. These disorders are associated with significant morbidity and high mortality linked to a high rate of suicide or attempted suicide. Behavioral disorders are also associated with an alteration of mentalizing capacities, that is the psychic process by which the adolescent imagines and interprets his behavior and that of others on the basis of mental states such as needs, desires, beliefs or feelings. The disorders are also associated with emotional dysregulation. To date, the psychopathological processes underlying behavioral disorders in adolescents are unknown and prevent from offering appropriate psychological care. Thus, it seems essential to characterize this clinical population by integrating both its intrapsychic representations and the physiological parameters of emotional regulation associated with it. This project is a first step towards a larger-scale research project aimed at evaluating treatment by TBM (therapies based on mentalization) in adolescents with behavioral disorders.

Conditions

Adolescent Behavior Disorder; Eye Movements

Keywords

Mentalisation; Emotion regulation; Adolescents; Neurophysiological parameters

Outcome Measures

Primary Outcomes (3)

• eye fixation duration evaluated with eyes tracker

  fixation duration (time in millisecond)

  12 months

• eye dwell time evaluated with eyes tracker

  dwell time (time in millisecond)

  12 months

• eye fixation count evaluated with eyes tracker

  fixation count ( time in millisecond)

  12 months

Secondary Outcomes (7)

• MASC Score

  12 months

• YSR score

  12 months

• RFQ-Y score

  12 months

• DERS score

  12 months

• ARSQ score

  12 months

Study Arms (1)

Mentalisation

EXPERIMENTAL

4 mentalisation groups will be defined: hypomentalisation, hypermentalisation, mentalisation correct and lack of mentalisation

Behavioral: Mentalisation

Interventions

Mentalisation BEHAVIORAL

Hypomentalisation, hypermentalisation, correct mentalisation, lack of mentalisation

Mentalisation

Eligibility Criteria

• Age: 12 Years - 18 Years
• Sex: all
• Healthy Volunteers: No
• Age Groups: Child (0-17), Adult (18-64)

You may qualify if:

• Teenage girls or boys aged 12 to 17
• Adolescent(s) with externalized behavioral disorder(s):
• running away, suicide attempts, self-aggression (scarification, self-mutilation), taking drugs, hetero-aggressive behavior, theft, conduct disorders sexual, oppositional behavior, lies, clastic anger.
• Non-objection of the adolescent to participate in the study.
• Written consent of the two holders of parental authority

You may not qualify if:

• Intellectually disabled
• Autism Spectrum Disorder
• Psychotic disorder

Sponsors & Collaborators

• Centre Hospitalier Universitaire de Besancon: lead

Study Sites (1)

CHU de Besançon

Besançon, France

RECRUITING

Related Publications (5)

• Szymanska M, Monnin J, Tio G, Vidal C, Girard F, Galdon L, Smith CC, Bifulco A, Nezelof S, Vulliez-Coady L. How do adolescents regulate distress according to attachment style? A combined eye-tracking and neurophysiological approach. Prog Neuropsychopharmacol Biol Psychiatry. 2019 Mar 8;89:39-47. doi: 10.1016/j.pnpbp.2018.08.019. Epub 2018 Aug 27.

  PMID: 30165119 BACKGROUND

• Taubner S, Volkert J, Gablonski TC, Rossouw T. [Mentalization-Based Treatment for Adolescents with Borderline Personality Disorder - Concept and Efficacy]. Prax Kinderpsychol Kinderpsychiatr. 2017 Jul;66(6):423-434. doi: 10.13109/prkk.2017.66.6.423. German.

  PMID: 28701091 BACKGROUND

• Sharp C, Pane H, Ha C, Venta A, Patel AB, Sturek J, Fonagy P. Theory of mind and emotion regulation difficulties in adolescents with borderline traits. J Am Acad Child Adolesc Psychiatry. 2011 Jun;50(6):563-573.e1. doi: 10.1016/j.jaac.2011.01.017. Epub 2011 Mar 9.

  PMID: 21621140 BACKGROUND

• Sharp C, Ha C, Carbone C, Kim S, Perry K, Williams L, Fonagy P. Hypermentalizing in adolescent inpatients: treatment effects and association with borderline traits. J Pers Disord. 2013 Feb;27(1):3-18. doi: 10.1521/pedi.2013.27.1.3.

  PMID: 23342954 BACKGROUND

• Quek J, Bennett C, Melvin GA, Saeedi N, Gordon MS, Newman LK. An investigation of the mentalization-based model of borderline pathology in adolescents. Compr Psychiatry. 2018 Jul;84:87-94. doi: 10.1016/j.comppsych.2018.04.005. Epub 2018 Apr 14.

  PMID: 29727808 BACKGROUND

MeSH Terms

Conditions

Emotional Regulation

Condition Hierarchy (Ancestors)

Self-Control; Social Behavior; Behavior

Study Officials

• Astrid Pozet, MS

  CHU Besancon, DRCI

  STUDY CHAIR

Central Study Contacts

Lauriane Vulliez, PR

CONTACT

(0033)0381218154; lvulliez@chu-besancon.fr

Julie Mathieu, MD

CONTACT

(0033)0381218154; jmathieu@chu-besancon.fr

Study Design

• Study Type: interventional
• Phase: not applicable
• Allocation: NA
• Masking: NONE
• Purpose: SUPPORTIVE CARE
• Intervention Model: SINGLE GROUP
• Sponsor Type: OTHER
• Responsible Party: SPONSOR

Study Record Dates

• First Submitted: March 27, 2023
• First Posted: April 19, 2023
• Study Start: June 26, 2023
• Primary Completion (Estimated): June 1, 2026
• Study Completion (Estimated): June 1, 2026
• Last Updated: September 19, 2024

Record last verified: 2024-09

Data Sharing

• IPD Sharing: Will not share

Locations

FR (1)