BMAC Loaded Collagen Jumping the Gap Around Immediate Implants
Assessment of Collagen Loaded With Bone Marrow Aspirate Concentrate Versus Autograft on Marginal Bone Changes Around Immediate Implants in Esthetic Zone. A Randomized Controlled Clinical Trial
1 other identifier
interventional
20
1 country
1
Brief Summary
The present study aims to evaluate the effect of utilization of BMAC/ collagen on marginal bone changes around immediate implants in the esthetic zone of maxilla. Methodology: Twenty dental implants will be installed in the esthetic zone and patients will be randomly divided into two groups: study group: The jumping gap surrounding the immediate implants will be grafted with BMAC/collagen, whereas in the control group, autograft from the chin will be used to fill the defect. Cone beam CT (CBCT) will be requested Preoperative, immediate and 4 months Postoperative for assessment of marginal bone changes around implants. .
Trial Health
Trial Health Score
Automated assessment based on enrollment pace, timeline, and geographic reach
participants targeted
Target at below P25 for not_applicable
Started Jan 2023
Typical duration for not_applicable
1 active site
Health score is calculated from publicly available data and should be used for screening purposes only.
Trial Relationships
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Study Timeline
Key milestones and dates
Study Start
First participant enrolled
January 25, 2023
CompletedFirst Submitted
Initial submission to the registry
April 5, 2023
CompletedFirst Posted
Study publicly available on registry
April 18, 2023
CompletedPrimary Completion
Last participant's last visit for primary outcome
October 1, 2024
CompletedStudy Completion
Last participant's last visit for all outcomes
December 1, 2024
CompletedMarch 28, 2024
March 1, 2024
1.7 years
April 5, 2023
March 27, 2024
Conditions
Outcome Measures
Primary Outcomes (1)
Marginal bone changes
Buccal bone height
4 months
Study Arms (2)
BMAC/ collagen
ACTIVE COMPARATORBone marrow aspirate concentrate loaded on collagen utilization for filling peri-implant gap around immediate dental implants in the Maxillary esthetic zone
Autograft
ACTIVE COMPARATORAutograft harvested from chin utilization for filling peri-implant gap around immediate dental implants in the Maxillary esthetic zone
Interventions
Bone marrow aspirate concentrate loaded on collagen in the peri-implant defect
Eligibility Criteria
You may qualify if:
- Patients with non- restorable teeth in esthetic zone
- Patients above 18 us
- Highly motivated patients.
You may not qualify if:
- patients with systemic diseases • immunocompromised patients . Patients with bleeding disorders
Contact the study team to confirm eligibility.
Sponsors & Collaborators
- Cairo Universitylead
Study Sites (1)
Walaa Kadry
Cairo, 02, Egypt
MeSH Terms
Interventions
Intervention Hierarchy (Ancestors)
Study Officials
- STUDY DIRECTOR
Eman Said
Lecturer at Faculty of Dentistry, Cairo University
Central Study Contacts
Ahmed Amin
CONTACT
Study Design
- Study Type
- interventional
- Phase
- not applicable
- Allocation
- RANDOMIZED
- Masking
- SINGLE
- Who Masked
- OUTCOMES ASSESSOR
- Purpose
- TREATMENT
- Intervention Model
- PARALLEL
- Sponsor Type
- OTHER
- Responsible Party
- PRINCIPAL INVESTIGATOR
- PI Title
- Lecturer of oral and Maxillofacial Surgery
Study Record Dates
First Submitted
April 5, 2023
First Posted
April 18, 2023
Study Start
January 25, 2023
Primary Completion
October 1, 2024
Study Completion
December 1, 2024
Last Updated
March 28, 2024
Record last verified: 2024-03