Active Screening of Arterial Hypertension by Community Outreach Workers in the Cayenne Metropolitan Area to Reduce the Incidence of Cardiovascular Disease

NCT05814068 | Unknown

• 1 other identifier: DEPIPREC
• Study Type: interventional
• Target: 50,000
• Locations: 0 countries
• Sites: N/A

Brief Summary

The main objective is to implement of a community-based primary care intervention against high blood pressure. We want to show that this intervention decreases the incidence of stroke in the community of agglomerations of the central coast of French Guiana, with a rapid effectiveness of about -30% at 2 years.

Conditions

High Blood Pressure

Keywords

High blood pressure; Precarity; community outreach workers; Cardiovascular disease; Health care

Outcome Measures

Primary Outcomes (1)

• To compare the incidence of stroke between before and after the start of the intervention according to PMSI data in resident persons in the agglomeration community of the central coast of French Guiana.

  To compare the incidence of stroke between before and after the intervention

  5 years

Secondary Outcomes (6)

• The incidence of acute coronary syndrome (ACS), transient ischemic attack, lower extremity arterial disease, aneurysm and end stage renal disease treated.

  comparison between before (over 5 years) and 1, 2 and 3 years after the beginning of the intervention according to PMSI data in the neighborhoods

• Stroke incidence

  comparison between before (over 5 years) and 1, 2 and 3 years after the beginning of the intervention according to PMSI data in the neighborhoods

• treatment adherence

  Inclusion

• Number of systolic and diastolic blood pressure measurements performed, number of new diagnoses and number of rediscoveries among those lost to follow-up during the intervention (number of people who give up on diagnosis or medical care)

  2 years

• Quantification of the evolution of the prescription of antihypertensive drugs in Guiana via data from the Social Security

  Before and 1, 2, and 3 years after the implementation of the intervention

Study Arms (1)

Intervention

EXPERIMENTAL

diagnosis and treatment of high blood pressure

Drug: antihypertensive drug treatment

Interventions

antihypertensive drug treatment DRUG

Patients with hypertension will be treated for it by their physician

Intervention

Eligibility Criteria

• Age: 18 Years+
• Sex: all
• Healthy Volunteers: Yes
• Age Groups: Adult (18-64), Older Adult (65+)

You may qualify if:

• Adults of at least 18 years old
• Residents of the agglomeration community of the central coast of French Guiana.

You may not qualify if:

• Person who has objected to participating in the study
• Person under guardianship or curatorship, persons under protective supervision

Sponsors & Collaborators

• Centre Hospitalier de Cayenne: lead

Related Publications (9)

• Mackenbach JP. Can we reduce health inequalities? An analysis of the English strategy (1997-2010). J Epidemiol Community Health. 2011 Jul;65(7):568-75. doi: 10.1136/jech.2010.128280. Epub 2011 Apr 1.

  PMID: 21459930 BACKGROUND

• Mackenbach JP. Has the English strategy to reduce health inequalities failed? Soc Sci Med. 2010 Oct;71(7):1249-1253. doi: 10.1016/j.socscimed.2010.07.014. Epub 2010 Aug 3. No abstract available.

  PMID: 20736133 BACKGROUND

• NCD Risk Factor Collaboration (NCD-RisC). Worldwide trends in hypertension prevalence and progress in treatment and control from 1990 to 2019: a pooled analysis of 1201 population-representative studies with 104 million participants. Lancet. 2021 Sep 11;398(10304):957-980. doi: 10.1016/S0140-6736(21)01330-1. Epub 2021 Aug 24.

  PMID: 34450083 BACKGROUND

• Rochemont DR, Mimeau E, Misslin-Tritsch C, Papaix-Puech M, Delmas E, Bejot Y, DeToffol B, Fournel I, Nacher M. The epidemiology and management of stroke in French Guiana. BMC Neurol. 2020 Mar 24;20(1):109. doi: 10.1186/s12883-020-01650-2.

  PMID: 32209060 BACKGROUND

• Rochemont DR, Lemenager P, Franck Y, Farhasmane A, Sabbah N, Nacher M. The epidemiology of acute coronary syndromes in French Guiana. Ann Cardiol Angeiol (Paris). 2021 Feb;70(1):7-12. doi: 10.1016/j.ancard.2020.09.032. Epub 2020 Oct 14.

  PMID: 33067006 BACKGROUND

• Valmy L, Gontier B, Parriault MC, Van Melle A, Pavlovsky T, Basurko C, Grenier C, Douine M, Adenis A, Nacher M. Prevalence and predictive factors for renouncing medical care in poor populations of Cayenne, French Guiana. BMC Health Serv Res. 2016 Jan 28;16:34. doi: 10.1186/s12913-016-1284-y.

  PMID: 26822003 BACKGROUND

• Van Melle A, Cropet C, Parriault MC, Adriouch L, Lamaison H, Sasson F, Duplan H, Richard JB, Nacher M. Renouncing care in French Guiana: the national health barometer survey. BMC Health Serv Res. 2019 Feb 6;19(1):99. doi: 10.1186/s12913-019-3895-6.

  PMID: 30728033 BACKGROUND

• Hart JT. Commentary: Can health outputs of routine practice approach those of clinical trials? Int J Epidemiol. 2001 Dec;30(6):1263-7. doi: 10.1093/ije/30.6.1263. No abstract available.

  PMID: 11821324 BACKGROUND

• Addo J, Ayerbe L, Mohan KM, Crichton S, Sheldenkar A, Chen R, Wolfe CD, McKevitt C. Socioeconomic status and stroke: an updated review. Stroke. 2012 Apr;43(4):1186-91. doi: 10.1161/STROKEAHA.111.639732. Epub 2012 Feb 23.

  PMID: 22363052 BACKGROUND

Related Links

• Article - Bulletin épidémiologique hebdomadaire n.d
• Rochemont DR, Dueymes JM, Roura R, Meddeb M, Couchoud C, Nacher M. End stage renal disease as a symptom of health inequalities in French Guiana.

MeSH Terms

Conditions

Hypertension; Cardiovascular Diseases

Condition Hierarchy (Ancestors)

Vascular Diseases

Study Officials

• Mathieu NACHER, PhD

  Centre Hospitalier de Cayenne

  PRINCIPAL INVESTIGATOR

Central Study Contacts

Mathieu NACHER, PhD

CONTACT

+594594395385; mathieu.nacher@ch-cayenne.fr

Devi ROCHEMONT, PhD

CONTACT

+594594395385; devi.rochemont@ch-cayenne.fr

Study Design

• Study Type: interventional
• Phase: not applicable
• Allocation: NA
• Masking: NONE
• Purpose: PREVENTION
• Intervention Model: SINGLE GROUP
• Sponsor Type: OTHER
• Responsible Party: SPONSOR

Study Record Dates

• First Submitted: March 3, 2023
• First Posted: April 14, 2023
• Study Start: May 1, 2023
• Primary Completion: May 1, 2025
• Study Completion: August 1, 2025
• Last Updated: April 14, 2023

Record last verified: 2023-02