Impact of Order of Movement on Nerve Root Function

NCT05813002 | Unknown DMC

• 1 other identifier: REC-22-06-04-S
• Study Type: interventional
• Target: 75
• Locations: 0 countries
• Sites: N/A

Brief Summary

the main objective of this study is to investigate if different neurodynamic test sequencing of the median nerve has a different impact on median nerve root function. We hypothesized that the order of median nerve neurodynamic movements would influence peak-to-peak amplitude and latency.

Conditions

Physical and Rehabilitation Medicine

Keywords

Randomized controlled trial; Neurodynamics; Evoked potential; Somatosensory

Outcome Measures

Primary Outcomes (1)

• Change in dermatomal somatosensory evoked potentials.

  In all dermatomes, 2 complete recording runs will be undertaken during each session with averages of 250 to 1200 cortical responses from scalp surface recording electrodes (C3'-C4' in a 10-20 electrode configuration) of the contralateral scalp to the stimulated dermatomes being stimulated. The impedance of ground and scalp electrodes will be maintained at \< 5 k Cutaneous areas of C5,C6,C7 sensory roots will be stimulated in lower limb with the electrical impulses of 0.2 ms duration, frequency of 3.3 Hz and intensity 3 times higher than the sensory threshold will be determined individually for each subject.

  baseline (pre-treatment) and immediately after the treatment

Study Arms (3)

standard neurodynamic sequence

ACTIVE COMPARATOR

Participants in the first group will receive the standard neurodynamic sequence. The starting position for this sequence will be shoulder in extension with lateral rotation, elbow in full flexion and wrist in neutral position. Passively the shoulder is abducted till 90 degrees followed by wrist extension then ended by elbow extension. Ipsilateral movement of the head bending till 45 degrees with movement of the wrist towards the body for 10 repetitions

Other: standard neural mobilization

Distal to proximal neurodynamic sequence

ACTIVE COMPARATOR

The second group participants will receive the distal to proximal neurodynamic sequence. For this sequence the starting position will be shoulder in full extension with lateral rotation, elbow fully extended and wrist in neutral position. the sequence will start with wrist extension, going to elbow extension, and ending with shoulder abduction. Ipsilateral movement of the head bending till 45 degrees with movement of the wrist towards the body for 10 repetitions

Other: Distal to proximal neural mobilization

proximal to distal neurodynamic sequence

ACTIVE COMPARATOR

The participants in the third experimental group will receive the proximal to distal sequence which will start with shoulder abduction, elbow extension and then wrist extension. The starting position is shoulder in extension and laterally rotated, elbow in full flexion, and wrist in neutral position. The shoulder will be passively mobilized to 90 degrees of abduction, elbow into full extension and wrist in full extension. Ipsilateral movement of the head bending till 45 degrees with movement of the wrist towards the body for 10 repetitions

Other: proximal to distal neural mobilization

Interventions

standard neural mobilization OTHER

is a movement-based intervention aimed at restoring the homeostasis in and around the nervous system.

standard neurodynamic sequence

Distal to proximal neural mobilization OTHER

is a distal to proximal movement-based intervention aimed at restoring the homeostasis in and around the nervous system.

Distal to proximal neurodynamic sequence

proximal to distal neural mobilization OTHER

is a proximal to distal movement-based intervention aimed at restoring the homeostasis in and around the nervous system.

proximal to distal neurodynamic sequence

Eligibility Criteria

• Age: 18 Years - 40 Years
• Sex: all
• Healthy Volunteers: Yes
• Age Groups: Adult (18-64)

You may qualify if:

• not currently experiencing any neck or dominant upper extremity symptoms.
• do not have a history significant for a chronic painful condition.
• do not using pain relievers.

You may not qualify if:

• inflammatory joint disease or other systemic pathologies.
• prior history of overt injury and surgery relating to the musculoskeletal system.
• disorder related to the spine and extremities.
• musculoskeletal pain in the last three months

Sponsors & Collaborators

• University of Sharjah: lead

Study Officials

• Ibrahim M moustafa, Professor

  University of Sharjah

  PRINCIPAL INVESTIGATOR

Central Study Contacts

Ibrahim M [imoustafa], Professor

CONTACT

+971502180024; iabuamr@sharjah.ac.ae

Study Design

• Study Type: interventional
• Phase: not applicable
• Allocation: RANDOMIZED
• Masking: SINGLE
• Who Masked: OUTCOMES ASSESSOR
• Masking Details: The assessor, who took the measurements for all groups will be blinded to the subject's group.
• Purpose: DIAGNOSTIC
• Intervention Model: PARALLEL
• Sponsor Type: OTHER
• Responsible Party: PRINCIPAL INVESTIGATOR
• PI Title: Professor-chair of Physiotherapy Department

Model Details: A prospective, parallel-group, randomized clinical trial participants will be randomly assigned to one of three different groups. One group will receive the standard neural mobilization, the second group will receive Distal-Proximal neural mobilization, and the third group will receive Proximal-Distal neural mobilization, all targeting the median nerve.

Study Record Dates

• First Submitted: April 1, 2023
• First Posted: April 14, 2023
• Study Start: April 1, 2023
• Primary Completion: May 1, 2023
• Study Completion: May 1, 2023
• Last Updated: April 14, 2023

Record last verified: 2023-04

Data Sharing

• IPD Sharing: Will not share