Skin Microbiome of Chinese Population Cohort Study

NCT05804851 | Active Not Recruiting DMC

• 1 other identifier: 20230103TL001
• Study Type: observational
• Target: 237
• Locations: 1 country
• Sites: 1

Brief Summary

This observational study aims to investigate the relationship between public health and the skin microbiome in the province of Zhejiang. Due to the lack of current research on the skin microbiome, the following general questions will be investigated in this study: 1) What connection exists between dietary practices and facial skin microbiome? 2) How do people's lifestyle routines affect the facial skin microbiome? 3) What effects does the altered living environment have on people's facial skin microbiomes? 4) How do the seasons affect people's facial skin microbiomes? Every 3 to 4 months, the participants' facial skin microbiota samples will be taken, and they will be asked to complete a survey.

Conditions

Skin Microbiome

Outcome Measures

Primary Outcomes (1)

• Changes in facial microbiota profiling

  Quantitative and qualitative analysis of bacteria population from the sample, rRNA and metagenome sequencing will be conducted on each sample

  Day 1, Day 90, Day 180, Day 270, and Day 360

Eligibility Criteria

• Age: 10 Years+
• Sex: all
• Healthy Volunteers: Yes
• Age Groups: Child (0-17), Adult (18-64), Older Adult (65+)
• Sampling Method: Non-Probability Sample

Study Population

The population of this study will be selected from people that reside in Zhejiang province, and they should fulfill the eligibility criteria.

You may qualify if:

• ages from 10+.

You may not qualify if:

• a severe medical history, including a history of surgery or medication, or serious illnesses such as cancer, liver disease, kidney disease, or craniocerebral trauma.
• recent medical treatment (topical antibiotics, corticosteroids, and other anti-inflammatory drugs within 4 weeks, and systemic antibiotics, corticosteroids, and other immunosuppressive drugs within 6 months)

Sponsors & Collaborators

• Westlake University: lead

Study Sites (1)

Westlake University

Hangzhou, Zhejiang, 310030, China

Location

Study Design

• Study Type: observational
• Observational Model: COHORT
• Time Perspective: PROSPECTIVE
• Target Duration: 1 Year
• Sponsor Type: OTHER
• Responsible Party: SPONSOR

Study Record Dates

• First Submitted: March 23, 2023
• First Posted: April 7, 2023
• Study Start: May 8, 2023
• Primary Completion: December 31, 2025
• Study Completion: December 31, 2025
• Last Updated: October 6, 2025

Record last verified: 2025-09

Data Sharing

• IPD Sharing: Will not share

Locations

CN (1)