Screening for Pancreatic Exocrine Insufficieny in Metabolic Associated Fatty Liver Disease Patients
1 other identifier
observational
70
0 countries
N/A
Brief Summary
to investigate the frequency of PEI in MAFLD
Trial Health
Trial Health Score
Automated assessment based on enrollment pace, timeline, and geographic reach
participants targeted
Target at P25-P50 for all trials
Started Jun 2023
Health score is calculated from publicly available data and should be used for screening purposes only.
Trial Relationships
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Study Timeline
Key milestones and dates
First Submitted
Initial submission to the registry
March 27, 2023
CompletedFirst Posted
Study publicly available on registry
April 7, 2023
CompletedStudy Start
First participant enrolled
June 1, 2023
CompletedPrimary Completion
Last participant's last visit for primary outcome
June 1, 2024
CompletedStudy Completion
Last participant's last visit for all outcomes
July 1, 2024
CompletedApril 7, 2023
March 1, 2023
1 year
March 27, 2023
March 27, 2023
Conditions
Keywords
Outcome Measures
Primary Outcomes (1)
investigate the frequency of PEI in MAFLD
screening for PEI by fecal elastase test in MAFLD patients
baseline
Interventions
screening for pancreatic exocrine insufficiency in MAFLD patients
Eligibility Criteria
MAFLD is diagnosed in patients when they have both hepatic steatosis and any of the following three metabolic conditions: overweight/obesity, diabetes mellitus, or evidence of metabolic dysregulation (MD) in lean individuals.
You may qualify if:
- Age greater than 18 years, Patients diagnosed as MAFLD
You may not qualify if:
- Patients use steatogenic medications, hormone replacement therapy or herbal products, any alcohol intake.
- Patients with any history of pancreatic diseases like acute pancreatitis, chronic pancreatitis and pancreatic surgery.
- Patients with any malignancy.
Contact the study team to confirm eligibility.
Sponsors & Collaborators
Related Publications (1)
Boga S, Koksal AR, Sen I, Kurul Yeniay M, Yilmaz Ozguven MB, Serin E, Erturk SM, Alkim H, Alkim C. Liver and pancreas: 'Castor and Pollux' regarding the relationship between hepatic steatosis and pancreas exocrine insufficiency. Pancreatology. 2020 Jul;20(5):880-886. doi: 10.1016/j.pan.2020.04.020. Epub 2020 May 19.
PMID: 32475757BACKGROUND
Related Links
MeSH Terms
Conditions
Condition Hierarchy (Ancestors)
Central Study Contacts
Study Design
- Study Type
- observational
- Observational Model
- CASE ONLY
- Time Perspective
- OTHER
- Sponsor Type
- OTHER
- Responsible Party
- PRINCIPAL INVESTIGATOR
- PI Title
- Ghada Ahmed Mahmoud Hammam
Study Record Dates
First Submitted
March 27, 2023
First Posted
April 7, 2023
Study Start
June 1, 2023
Primary Completion
June 1, 2024
Study Completion
July 1, 2024
Last Updated
April 7, 2023
Record last verified: 2023-03