Brief Summary

The aim of this study was to analyse the level of cognitive functioning of patients with history of suicidal behaviour suffering from depression and schizophrenia, and to evaluate their oxidative stress parameters and selected biochemical parameters on the basis of bloodwork.

Trial Health

100

On Track

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Enrollment

120

participants targeted

Target at P50-P75 for all trials

Timeline

Completed

Started Sep 2016

Typical duration for all trials

Status

completed

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

Click on a node to explore related trials.

Study Timeline

Key milestones and dates

3.2 years study duration

Study Start

First participant enrolled

September 1, 2016

Completed

3.2 years until next milestone

Primary Completion

Last participant's last visit for primary outcome

October 31, 2019

Completed

Same day until next milestone

Study Completion

Last participant's last visit for all outcomes

October 31, 2019

Completed

3.2 years until next milestone

First Submitted

Initial submission to the registry

January 24, 2023

Completed

2 months until next milestone

First Posted

Study publicly available on registry

April 7, 2023

Completed

Last Updated

April 7, 2023

Status Verified

March 1, 2023

Enrollment Period

3.2 years

First QC Date

January 24, 2023

Last Update Submit

March 27, 2023

Conditions

Suicidal Behaviour Cognitive Functions Confusion

Keywords

depressionschizophreniabiochemical blood testsoxidative stress pathway

Outcome Measures

Primary Outcomes (1)

At the first stage, the participants were interviewed by the certified clinical psychologist. M.I.N.I. 7.0.2 interview was conducted with each patient to verify the intensification of suicidal behaviour.
The setting of the study assumed that the procedure started in the first 48 h after the hospital admission. Based on the scores M.I.N.I.7.0.2 the patients were classified into one of eight groups: * control groups displaying no suicidal behaviour (G0K - women and G0M - men), the result of M.I.N.I. 7.0.2 test was zero points; * groups experiencing suicidal thoughts without a tendency of implementation (G1K - women and G1M - men), the result of M.I.N.I. 7.0.2 test was 1 to 8 points; * groups experiencing suicidal thoughts with a tendency of implementation (G2K - women and G2M - men), the result of M.I.N.I. 7.0.2 test was 9 to 16 points; * groups after a suicide attempt (G3K - women and G3M - men), the result of M.I.N.I. 7.0.2 test was equal to or greater than 17 points.
in the first 48 hours after the hospital admission

Secondary Outcomes (4)

The second stage of the study consisted of biochemical blood tests - vitamins
1 week
The second stage of the study consisted of biochemical blood tests - ions
1 week
The second stage of the study consisted of biochemical blood tests - total cholesterol, LDL, HDL, TG
1 week
The second stage of the study consisted of biochemical blood tests - oxidative stress
1 week

Other Outcomes (2)

The third stage of the study consisted of the participants completing a Cogstate (full name of the test) computerized test to verify their cognitive functioning. Part 1.
between 20 to 45 minutes
The third stage of the study consisted of the participants completing a Cogstate (full name of the test) computerized test to verify their cognitive functioning. Part 2.
between 20 to 45 minutes

Study Arms (8)

G1K-women

The G1K group consisted of women experiencing suicidal thoughts without a tendency of implementation, in whom the result of M.I.N.I. 7.0.2 test was 1 to 8 points (n=14)