NCT05800158

Brief Summary

This prospective clinical performance study is a non-interventional, multi-center study to evaluate the assay performance of the COVID-19 test using upper respiratory specimens. Prospectively collected nasopharyngeal and anterior nasal swabs will be collected from each participant recruited in the study.

Trial Health

87
On Track

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Enrollment
1,076

participants targeted

Target at P75+ for all trials

Timeline
Completed

Started Apr 2023

Shorter than P25 for all trials

Geographic Reach
1 country

11 active sites

Status
completed

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

Click on a node to explore related trials.

Study Timeline

Key milestones and dates

First Submitted

Initial submission to the registry

March 23, 2023

Completed
13 days until next milestone

First Posted

Study publicly available on registry

April 5, 2023

Completed
7 days until next milestone

Study Start

First participant enrolled

April 12, 2023

Completed
4 months until next milestone

Primary Completion

Last participant's last visit for primary outcome

August 10, 2023

Completed
Same day until next milestone

Study Completion

Last participant's last visit for all outcomes

August 10, 2023

Completed
Last Updated

October 18, 2023

Status Verified

October 1, 2023

Enrollment Period

4 months

First QC Date

March 23, 2023

Last Update Submit

October 16, 2023

Conditions

Outcome Measures

Primary Outcomes (2)

  • Clinical performance evaluation of the COVID-19 test

    Clinical performance evaluation of the COVID-19 test using a composite comparator approach with upper respiratory specimens to meet PPA and NPA requirements.

    Between April 2023 and August 2023

  • Identification of adverse events

    Identify any adverse events or complications associated with the COVID-19 test

    Between April 2023 and August 2023

Study Arms (1)

SARS-CoV-2

Nasopharyngeal and anterior nasal swabs collected from symptomatic individuals suspected of COVID-19 by their health care provider.

Diagnostic Test: Applied Biosystems™ TaqPath™ COVID-19 Diagnostic PCR Kit

Interventions

A reverse transcription, real-time polymerase chain reaction (RT-qPCR) test for the qualitative detection of SARS-CoV-2.

SARS-CoV-2

Eligibility Criteria

Sexall
Healthy VolunteersNo
Age GroupsChild (0-17), Adult (18-64), Older Adult (65+)
Sampling MethodProbability Sample
Study Population

The study population will be composed of participants suspected of COVID-19. After a subject is determined eligible for study participation (met inclusion criteria and did not meet exclusion criteria) and has completed the institutional review board (IRB)-approved informed consent form process (or assent, as age appropriate), the subject is enrolled into the study.

You may qualify if:

  • Ability to provide informed consent or assent (as age-appropriate). Stated willingness and ability to comply with the study procedures including nasopharyngeal and anterior nasal swab collection.
  • Individuals with at least one of the following COVID-19 symptoms:
  • fever or chills
  • congestion or runny nose
  • headache or fatigue
  • muscle or body aches
  • b. new loss of taste or smell c. a new or worsening cough or sore throat d. shortness of breath or difficulty breathing e. decrease in appetite, nausea, vomiting, diarrhea.
  • Subjects suspected of having COVID-19 symptoms for seven (7) or fewer days.

You may not qualify if:

  • Participants meeting the following criterion will be excluded from the study:
  • Subjects suspected of having COVID-19 symptoms for greater than seven (7) days.
  • Subjects who have provided upper respiratory tract samples for other clinical studies within twenty-four (24) hours

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Study Sites (11)

KUR Research at Exer Urgent Care - Manhattan Beach

Manhattan Beach, California, 90266, United States

Location

KUR Research at Exer Urgent Care - Redondo Beach

Redondo Beach, California, 90277, United States

Location

Medical Center for Clinical Research

San Diego, California, 92120, United States

Location

Multi Specialty Research Associates

Lake City, Florida, 32055, United States

Location

D&H National Research Centers

Miami, Florida, 33155, United States

Location

Clinical Research Center of Nevada

Las Vegas, Nevada, 89106, United States

Location

KUR Research at AFC Urgent Care

The Bronx, New York, 10465, United States

Location

KUR Research at AFC Urgent Care

Easley, South Carolina, 29640, United States

Location

KUR Research at AFC Urgent Care

Powdersville, South Carolina, 29611, United States

Location

ClinSearch

Chattanooga, Tennessee, 37421, United States

Location

KUR Research at CityDoc Urgent Care

McKinney, Texas, 75204, United States

Location

Biospecimen

Retention: SAMPLES WITHOUT DNA

nasopharyngeal and anterior nasal swabs

MeSH Terms

Conditions

COVID-19Coronavirus Infections

Condition Hierarchy (Ancestors)

Pneumonia, ViralPneumoniaRespiratory Tract InfectionsInfectionsVirus DiseasesCoronaviridae InfectionsNidovirales InfectionsRNA Virus InfectionsLung DiseasesRespiratory Tract Diseases

Study Design

Study Type
observational
Observational Model
CASE ONLY
Time Perspective
PROSPECTIVE
Sponsor Type
INDUSTRY
Responsible Party
SPONSOR

Study Record Dates

First Submitted

March 23, 2023

First Posted

April 5, 2023

Study Start

April 12, 2023

Primary Completion

August 10, 2023

Study Completion

August 10, 2023

Last Updated

October 18, 2023

Record last verified: 2023-10

Data Sharing

IPD Sharing
Will not share

Locations