NCT05797428

Brief Summary

Logotherapy can help people find their meaning in life and help people reduce their suicidal ideation. Suicide was the second leading cause of death for 15-24 year-olds. Logotherapy can increase exploration of meaning in life for adolescents and prevent them from attempting suicide. However, most research only explored the effects of logotherapy on meaning in life and depression in adolescents with mood disorders. There is a lack of research to explore the effects of logotherapy on anxiety and suicidal ideation in adolescents. Therefore, this study will explore the effects of logotherapy on meaning in life, depression, anxiety and suicidal ideation in adolescents with mood disorders. This study will carry on for two years and the sample will be recruited from the adolescents' outpatient clinic of psychiatric department in hospitals. The first and second year of the study will use a single-blind randomized controlled trial approach, the aim is to evaluate the short-term and longitudinal effects of logotherapy meaning in life, depression, anxiety and suicidal ideation in adolescents with mood disorders, the sample will collect 120 adolescents with mood disorders, and will use four instruments for testing the logotherapy intervention. The four instruments are: (1) Purpose in life Test, (2) Beck Depression Inventory II, (3) Beck Anxiety Inventory, (4) Beck Scale for Suicide Ideation. Data will be analyzed using the Statistic Package for the Social Science. The result of this study will be applied to the mental health team in the clinical psychiatric department for taking care of patients, and help adolescents with mood disorders to find their meaning in life, further, to reduce their depression, anxiety and suicidal ideation.

Trial Health

57
Monitor

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Trial has exceeded expected completion date
Enrollment
120

participants targeted

Target at P50-P75 for not_applicable

Timeline
Completed

Started May 2023

Typical duration for not_applicable

Geographic Reach
1 country

1 active site

Status
recruiting

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

Click on a node to explore related trials.

Study Timeline

Key milestones and dates

First Submitted

Initial submission to the registry

March 20, 2023

Completed
15 days until next milestone

First Posted

Study publicly available on registry

April 4, 2023

Completed
2 months until next milestone

Study Start

First participant enrolled

May 19, 2023

Completed
2.2 years until next milestone

Primary Completion

Last participant's last visit for primary outcome

July 31, 2025

Completed
Same day until next milestone

Study Completion

Last participant's last visit for all outcomes

July 31, 2025

Completed
Last Updated

March 18, 2025

Status Verified

February 1, 2025

Enrollment Period

2.2 years

First QC Date

March 20, 2023

Last Update Submit

March 16, 2025

Conditions

Keywords

logotherapydepressionanxietysuicidal ideationadolescent

Outcome Measures

Primary Outcomes (16)

  • Purpose in life Test-1

    There are 20 items in this scale, which are divided into four dimensions: quality of life, value of life, purpose of life, and freedom of life. Each question is scored on a scale of 1-5, and the total score ranges from 20-100, with higher scores representing a higher sense of meaning in life.

    pre-test (before intervention)

  • Purpose in life Test-2

    There are 20 items in this scale, which are divided into four dimensions: quality of life, value of life, purpose of life, and freedom of life. Each question is scored on a scale of 1-5, and the total score ranges from 20-100, with higher scores representing a higher sense of meaning in life.

    post-test 1 (the week after the intervention)

  • Purpose in life Test-3

    There are 20 items in this scale, which are divided into four dimensions: quality of life, value of life, purpose of life, and freedom of life. Each question is scored on a scale of 1-5, and the total score ranges from 20-100, with higher scores representing a higher sense of meaning in life.

    post-test 2 (three months after the intervention)

  • Purpose in life Test-4

    There are 20 items in this scale, which are divided into four dimensions: quality of life, value of life, purpose of life, and freedom of life. Each question is scored on a scale of 1-5, and the total score ranges from 20-100, with higher scores representing a higher sense of meaning in life.

    post-test 3 (nine months after the intervention)

  • Beck Depression Inventory II-1

    This scale has a total of 21 items. Each item is scored from 0-3 points, and the total score ranges from 0-63 points. The higher the score, the higher the degree of depression.

    pre-test (before intervention)

  • Beck Depression Inventory II-2

    This scale has a total of 21 items. Each item is scored from 0-3 points, and the total score ranges from 0-63 points. The higher the score, the higher the degree of depression.

    post-test 1 (the week after the intervention)

  • Beck Depression Inventory II-3

    This scale has a total of 21 items. Each item is scored from 0-3 points, and the total score ranges from 0-63 points. The higher the score, the higher the degree of depression.

    post-test 2 (three months after the intervention)

  • Beck Depression Inventory II-4

    This scale has a total of 21 items. Each item is scored from 0-3 points, and the total score ranges from 0-63 points. The higher the score, the higher the degree of depression.

    post-test 3 (nine months after the intervention)

  • Beck Anxiety Inventory-1

    This scale contains 21 items and each item is scored from 0-3 points. The total score ranges from 0-63 points. The higher the score, the higher the degree of anxiety.

    pre-test (before intervention)

  • Beck Anxiety Inventory-2

    This scale contains 21 items and each item is scored from 0-3 points. The total score ranges from 0-63 points. The higher the score, the higher the degree of anxiety.

    post-test 1 (the week after the intervention)

  • Beck Anxiety Inventory-3

    This scale contains 21 items and each item is scored from 0-3 points. The total score ranges from 0-63 points. The higher the score, the higher the degree of anxiety.

    post-test 2 (three months after the intervention)

  • Beck Anxiety Inventory-4

    This scale contains 21 items and each item is scored from 0-3 points. The total score ranges from 0-63 points. The higher the score, the higher the degree of anxiety.

    post-test 3 (nine months after the intervention)

  • Beck Scale for Suicide Ideation-1

    This scale contains 21 items. The first 19 items mainly measure the severity of the individual's attitudes, behaviors, and plans for suicide in the past week. Each question is calculated on a scale of 0-2, and the total score ranges from 0-38, with higher scores indicating stronger suicidal ideation. The last two questions, which are not counted, ask about the number of previous suicide attempts and the severity of the intention of the last suicide attempt.

    pre-test (before intervention)

  • Beck Scale for Suicide Ideation-2

    This scale contains 21 items. The first 19 items mainly measure the severity of the individual's attitudes, behaviors, and plans for suicide in the past week. Each question is calculated on a scale of 0-2, and the total score ranges from 0-38, with higher scores indicating stronger suicidal ideation. The last two questions, which are not counted, ask about the number of previous suicide attempts and the severity of the intention of the last suicide attempt.

    post-test 1 (the week after the intervention)

  • Beck Scale for Suicide Ideation-3

    This scale contains 21 items. The first 19 items mainly measure the severity of the individual's attitudes, behaviors, and plans for suicide in the past week. Each question is calculated on a scale of 0-2, and the total score ranges from 0-38, with higher scores indicating stronger suicidal ideation. The last two questions, which are not counted, ask about the number of previous suicide attempts and the severity of the intention of the last suicide attempt.

    post-test 2 (three months after the intervention)

  • Beck Scale for Suicide Ideation-4

    This scale contains 21 items. The first 19 items mainly measure the severity of the individual's attitudes, behaviors, and plans for suicide in the past week. Each question is calculated on a scale of 0-2, and the total score ranges from 0-38, with higher scores indicating stronger suicidal ideation. The last two questions, which are not counted, ask about the number of previous suicide attempts and the severity of the intention of the last suicide attempt.

    post-test 3 (nine months after the intervention)

Study Arms (2)

Logotherapy

EXPERIMENTAL

3 months of logotherapy intervention by interviewing with the participant, once every two weeks, about 1-2 hours each time, a total of 6 times of logotherapy.

Other: logotherapy

Routine psychiatric outpatient treatment

NO INTERVENTION

Will not provide any logotherapy. Just routine psychiatric outpatient treatment.

Interventions

The logotherapy is carried out in an individual way in this study. The full-time assistant will give the experimental group 3 months of logotherapy intervention by interviewing with the participant, once every two weeks, about 1-2 hours each time, a total of 6 times of logotherapy to guide the participant to find the meaning of his life and value.The location is mainly in the hospital when the participant has to return for consultation, or at the participant's home.

Logotherapy

Eligibility Criteria

Age15 Years - 24 Years
Sexall
Healthy VolunteersNo
Age GroupsChild (0-17), Adult (18-64)

You may qualify if:

  • Patients with mood disorders (such as depression, bipolar disorder) diagnosed by a psychiatrist.
  • Patient Health Questionnaire-9 items (PHQ-9) score 5-19 points (indicating mild depression to moderate to severe depression)
  • Agree to participate in logotherapy
  • Able to participate in logotherapy

You may not qualify if:

  • Patients with severe emotional disorders who cannot participate in logotherapy.
  • Those who have severe psychopathological phenomena and cannot judge reality or those who are mentally deficient.
  • Those who have serious suicidal ideation or clear suicide plan are not suitable for interview

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Study Sites (1)

Kaohsiung Chang Gung Memorial Hospital

Kaohsiung City, Niaosong District, 833, Taiwan

RECRUITING

MeSH Terms

Conditions

DepressionAnxiety DisordersSuicidal Ideation

Interventions

Logotherapy

Condition Hierarchy (Ancestors)

Behavioral SymptomsBehaviorMental DisordersSuicideSelf-Injurious Behavior

Intervention Hierarchy (Ancestors)

PsychotherapyBehavioral Disciplines and Activities

Study Officials

  • Fan-Ko Sun, PhD

    Second Degree Bachelor of Science in nursing, National Taiwan University

    STUDY CHAIR

Central Study Contacts

Chun-Ying Chiang, PhD

CONTACT

Study Design

Study Type
interventional
Phase
not applicable
Allocation
RANDOMIZED
Masking
DOUBLE
Who Masked
PARTICIPANT, OUTCOMES ASSESSOR
Purpose
SUPPORTIVE CARE
Intervention Model
PARALLEL
Sponsor Type
OTHER
Responsible Party
SPONSOR

Study Record Dates

First Submitted

March 20, 2023

First Posted

April 4, 2023

Study Start

May 19, 2023

Primary Completion

July 31, 2025

Study Completion

July 31, 2025

Last Updated

March 18, 2025

Record last verified: 2025-02

Data Sharing

IPD Sharing
Will not share

Locations