The Analgesic Efficacy of Ultrasound Guided Adductor Canal Block Versus 4 in 1 Block in Patients Undergoing Knee Surgeries: A Comparative Randomized Double Blinded Study .

NCT05794685 | Completed

• 1 other identifier: FMBSUREC/12022023/saad
• Study Type: interventional
• Target: 40
• Locations: 1 country
• Sites: 1

Brief Summary

Knee surgeries are associated with severe postoperative pain. Improper pain management affects patients' psychological status with prolongation of hospital stay time and rehabilitation period, with the possibility of progression of the acute pain to chronic pain (McCartney CJ, Nelligan K., 2014). Many Pain management options following these surgeries are available: non-opioid analgesics, opioids and regional anesthesia techniques (epidural and peripheral nerve block). Multi-modal analgesia is considered the best option for pain management in knee surgeries. As non-opioid analgesics alone are not effective enough while opioids alone are associated with many risk factors: nausea, vomiting, decrease intestinal motility and respiratory depression with possibility of addiction (Goode VM, Morgan B, et al, 2019)

Conditions

Comparing the Analgesic Outcome by ( 4 in 1 Block ) & ( Adductor Canal Block )

Keywords

ultrasound guided adductor canal block .; 4 in 1 block .; knee surgeries .

Outcome Measures

Primary Outcomes (4)

• Postoperative pain score: resting and dynamic .

  Postoperative pain score: resting and dynamic pain using NRS at postoperative 6 hours.Numerical rating scales (NRSs) are the simplest and most commonly used scales. The numerical scale is most commonly 0 to 10, with 0 being "no pain" and 10 being "the worst pain imaginable." The patient picks (verbal version) or draws a circle around (written version) the number that best describes the pain dimension, usually intensity.

  6 hours Postoperative

• Postoperative pain score: resting and dynamic

  Postoperative pain score: resting and dynamic pain using NRS at postoperative 12 hours.

  12 hours post operative

• Postoperative pain score: resting and dynamic

  Postoperative pain score: resting and dynamic pain using NRS at postoperative 18 hours.

  18 hours post operative

• Postoperative pain score: resting and dynamic

  Postoperative pain score: resting and dynamic pain using NRS at postoperative 24 hours.

  24 hours post operative.

Secondary Outcomes (3)

• Change of blood pressure .

  Intraoperative

• Change of heart rate .

  Intraoperative

• Postoperative opioid requirements .

  24 hours post operative

Study Arms (2)

adductor canal block

ACTIVE COMPARATOR

adductor canal block : patients will receive an injection of 30 ml of .25% of Bupivacaine including 4mg of dexamethasone at a point anterior to the femoral artery, deep to the sartorius muscle

Procedure: adductor canal block; Procedure: 4 in one block

4 in one block

ACTIVE COMPARATOR

4 in one block : patients will receive an injection of 30 ml of .25% of Bupivacaine including 4mg dexamethasone at the adductor hiatus where the descending genicular artery branches from superficial femoral artery .

Procedure: adductor canal block; Procedure: 4 in one block

Interventions

adductor canal block PROCEDURE

patients will receive an injection of 30 ml of .25% of Bupivacaine including 4mg of dexamethasone at a point anterior to the femoral artery, deep to the sartorius muscle (adductor canal block).

4 in one block; adductor canal block

4 in one block PROCEDURE

patients will receive an injection of 30 ml of .25% of Bupivacaine including 4mg dexamethasone at the adductor hiatus where the descending genicular artery branches from superficial femoral artery (4 in one block).

4 in one block; adductor canal block

Eligibility Criteria

• Age: 20 Years - 60 Years
• Sex: all
• Healthy Volunteers: Yes
• Age Groups: Adult (18-64)

You may qualify if:

• Both sexes.
• ASA grade 1 and 2.
• Age group between 20-60 years.
• Patients who will undergo knee surgeries under neuroaxial anesthesia.

You may not qualify if:

• Patient refusal.
• Patients who are allergic to any of study drugs.
• Absolute contraindication causes to spinal anesthesia due to coagulopathy, severe aortic/mitral stenosis, or active infection at site of injection

Sponsors & Collaborators

• Mahmoud Hussein Bahr: lead

Study Sites (1)

Faculty of medicine.Beni-suef university

Cairo, 62511, Egypt

Location

Study Design

• Study Type: interventional
• Phase: not applicable
• Allocation: RANDOMIZED
• Masking: SINGLE
• Who Masked: PARTICIPANT
• Purpose: TREATMENT
• Intervention Model: PARALLEL
• Sponsor Type: OTHER
• Responsible Party: SPONSOR INVESTIGATOR
• PI Title: Associated Professor of Anesthesiology and Surgical Intensive Care and pain medicine

Model Details: Comparative Randomized Study between 2 groups

Study Record Dates

• First Submitted: March 2, 2023
• First Posted: April 3, 2023
• Study Start: April 1, 2023
• Primary Completion: December 1, 2023
• Study Completion: January 1, 2024
• Last Updated: August 19, 2024

Record last verified: 2024-08

Data Sharing

• IPD Sharing: Will not share

Locations

EG (1)