Gamified Adaptive Approach Bias Modification on Individuals With Methamphetamine Use History
1 other identifier
interventional
139
1 country
12
Brief Summary
A randomized controlled trial will be conducted to investigate whether a proposed algorithm that adjusts the congruency ratio based on the user's performance and difficulty can enhance the effectiveness of approach bias modification. Methamphetamine users will be recruited and randomized into an algorithm group, a standard group, and a control group.
Trial Health
Trial Health Score
Automated assessment based on enrollment pace, timeline, and geographic reach
participants targeted
Target at P50-P75 for not_applicable
Started Mar 2023
Shorter than P25 for not_applicable
12 active sites
Health score is calculated from publicly available data and should be used for screening purposes only.
Trial Relationships
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Study Timeline
Key milestones and dates
First Submitted
Initial submission to the registry
March 6, 2023
CompletedStudy Start
First participant enrolled
March 10, 2023
CompletedFirst Posted
Study publicly available on registry
April 3, 2023
CompletedPrimary Completion
Last participant's last visit for primary outcome
July 15, 2023
CompletedStudy Completion
Last participant's last visit for all outcomes
July 15, 2023
CompletedJuly 18, 2023
July 1, 2023
4 months
March 6, 2023
July 17, 2023
Conditions
Outcome Measures
Primary Outcomes (3)
Cue induced craving for methamphetamine
The cue-induced craving was assessed by showing the participants images related to methamphetamine (methamphetamine crystals, powders, and paraphernalia) on a smartphone and asking them to rate their cravings on a 0-10 visual analog scale (0 being least craved and 10 being most craved).
Baseline
Cue induced craving for methamphetamine
The cue-induced craving was assessed by showing the participants images related to methamphetamine (methamphetamine crystals, powders, and paraphernalia) on a smartphone and asking them to rate their cravings on a 0-10 visual analog scale (0 being least craved and 10 being most craved).
Immediately Post-intervention
Cue induced craving for methamphetamine
The cue-induced craving was assessed by showing the participants images related to methamphetamine (methamphetamine crystals, powders, and paraphernalia) on a smartphone and asking them to rate their cravings on a 0-10 visual analog scale (0 being least craved and 10 being most craved).
16 week from baseline assesment
Study Arms (3)
Adaptive Approach Bias Modification
EXPERIMENTALStatic Approach Bias Modification
EXPERIMENTALControl
NO INTERVENTIONInterventions
In the static approach bias modification, users were instructed to swipe upward when they see portrait format images and swipe downward when they see landscape format images. A shrinking animation comes after swiping upward to simulate the visual effect of moving away (approach), and a growing animation comes after swiping downward to simulate the visual effect of moving towards (avoidance). Two types of images, namely drug-related and non-drug-related, were used in the training. The drug-related images were related to methamphetamine (methamphetamine crystals, powders, and paraphernalia), and the non-drug-related images were related to healthy lifestyles (wealth, sports, gourmet, family activities, etc).
In the adaptive approach bias modification, users were instructed to swipe upward when they see portrait format images and swipe downward when they see landscape format images. A shrinking animation comes after swiping upward to simulate the visual effect of moving away (approach), and a growing animation comes after swiping downward to simulate the visual effect of moving towards (avoidance). Two types of images, namely drug-related and non-drug-related, were used in the training. The drug-related images were related to methamphetamine (methamphetamine crystals, powders, and paraphernalia), and the non-drug-related images were related to healthy lifestyles (wealth, sports, gourmet, family activities, etc). An algorithm continuously monitors the performance of the user and adjusts the ratio of congruent and incongruent trials accordingly to attain a desired difficulty curve.
Eligibility Criteria
You may qualify if:
- having a history of methamphetamine use of at least one year
You may not qualify if:
- could not fluently operate an Android or an iOS smartphone
- having mental health conditions other than MUD
Contact the study team to confirm eligibility.
Sponsors & Collaborators
Study Sites (12)
Gao Ping Town Community Drug Rehabilitation Center
Luocheng, Sichuan, China
Han Zhou Street Community Drug Rehabilitation Center
Luocheng, Sichuan, China
Jin Lun Town Community Drug Rehabilitation Center
Luocheng, Sichuan, China
Jin Yan Street Community Drug Rehabilitation Center
Luocheng, Sichuan, China
Jin Yu Town Community Drug Rehabilitation Center
Luocheng, Sichuan, China
Lian Shan Town Community Drug Rehabilitation Center
Luocheng, Sichuan, China
Nan Feng Town Community Drug Rehabilitation Center
Luocheng, Sichuan, China
San Shui Town Community Drug Rehabilitation Center
Luocheng, Sichuan, China
Sanxingdui Town Community Drug Rehabilitation Center
Luocheng, Sichuan, China
SixTwentySix Service Center, Luo Cheng Street, Guanghan City
Luocheng, Sichuan, China
Xiang Yang Town Community Drug Rehabilitation Center
Luocheng, Sichuan, China
Xiao Han Town Community Drug Rehabilitation Center
Luocheng, Sichuan, China
MeSH Terms
Conditions
Condition Hierarchy (Ancestors)
Study Design
- Study Type
- interventional
- Phase
- not applicable
- Allocation
- RANDOMIZED
- Masking
- NONE
- Purpose
- TREATMENT
- Intervention Model
- PARALLEL
- Sponsor Type
- OTHER
- Responsible Party
- SPONSOR
Study Record Dates
First Submitted
March 6, 2023
First Posted
April 3, 2023
Study Start
March 10, 2023
Primary Completion
July 15, 2023
Study Completion
July 15, 2023
Last Updated
July 18, 2023
Record last verified: 2023-07