NCT05792358

Brief Summary

This study evaluates the efficacy of wet cupping therapy in patients with ankylosing spondylitis.Wet cupping therapy will be applied to half of the patients plus routine pharmaceutical treatment while the other half will receive only pharmaceutics

Trial Health

87
On Track

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Enrollment
100

participants targeted

Target at P50-P75 for not_applicable

Timeline
Completed

Started Feb 2023

Typical duration for not_applicable

Geographic Reach
1 country

1 active site

Status
completed

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

Click on a node to explore related trials.

Study Timeline

Key milestones and dates

Study Start

First participant enrolled

February 1, 2023

Completed
1 month until next milestone

First Submitted

Initial submission to the registry

March 7, 2023

Completed
24 days until next milestone

First Posted

Study publicly available on registry

March 31, 2023

Completed
2.3 years until next milestone

Primary Completion

Last participant's last visit for primary outcome

July 1, 2025

Completed
4 months until next milestone

Study Completion

Last participant's last visit for all outcomes

October 30, 2025

Completed
Last Updated

February 24, 2026

Status Verified

February 1, 2026

Enrollment Period

2.4 years

First QC Date

March 7, 2023

Last Update Submit

February 21, 2026

Conditions

Ankylosing Spondylitis

Keywords

Ankylosing SpondylitisWet cupping therapyBasfiBasdaiVas

Outcome Measures

Primary Outcomes (3)

  • BASFI

    Change in the scores of The Bath Ankylosing Spondylitis Functional Index

    At 0 and 3 months

  • BASDAI

    Change in the scores of The Bath Ankylosing Spondylitis Disease Activity Index

    At 0 and 3 months

  • VAS

    Change in the scores of Visual Analogue Scale

    At 0 and 3 months

Secondary Outcomes (1)

  • Schober

    At 0 and 3 months

Study Arms (2)

Wet cupping arm

EXPERIMENTAL

This arm is the interventiom group and will receive three consecutive sessions of wet cupping therapy once a month.

Procedure: wet cupping therapy

Control arm

NO INTERVENTION

This arm is the control group and will not receive any intervention other than the routine medications

Interventions

wet cupping therapyPROCEDURE

wet cupping therapy will be applied to participants in this arm for three sessions once a month

Wet cupping arm

Eligibility Criteria

Age18 Years - 65 Years
Sexall
Healthy VolunteersYes
Age GroupsAdult (18-64), Older Adult (65+)

You may qualify if:

  • Clinical diagnosis of ankylosing spondylitis 18-65 years of age Consent to participate

You may not qualify if:

  • Any ongoing medical treatment other than NSAIDs Pregnancy At least one contraindication to WCT that was detected in subject's history or in the routine blood examinations prior to enrollment (Hgb \<9.5; INR\> 1.2; history of hemophobia, bleeding disorder, malignant disorder).

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Study Sites (1)

Karabuk University

Karabük, Turkey (Türkiye)

Location

MeSH Terms

Conditions

Spondylitis, Ankylosing

Condition Hierarchy (Ancestors)

Axial SpondyloarthritisSpondylarthropathiesSpondylarthritisSpondylitisSpinal DiseasesBone DiseasesMusculoskeletal DiseasesAnkylosisJoint DiseasesArthritis

Study Design

Study Type
interventional
Phase
not applicable
Allocation
RANDOMIZED
Masking
NONE
Purpose
TREATMENT
Intervention Model
PARALLEL
Sponsor Type
OTHER
Responsible Party
PRINCIPAL INVESTIGATOR
PI Title
Head of the complementary medicine department

Study Record Dates

First Submitted

March 7, 2023

First Posted

March 31, 2023

Study Start

February 1, 2023

Primary Completion

July 1, 2025

Study Completion

October 30, 2025

Last Updated

February 24, 2026

Record last verified: 2026-02

Locations

TU(1)