Teletechnology-assisted Home-based Exercise Program for Severe COVID-19

NCT05778344 | Completed

• 1 other identifier: 202106133RIND
• Study Type: interventional
• Target: 20
• Locations: 1 country
• Sites: 1

Brief Summary

The aim of this study was to investigate the efficacy of a home-based pulmonary rehabilitation program with the support of teletechnology in COVID-19 survivors. The main questions it aims to answer were:

• The change of six-minute walk distance
• The change of time of one-minute sit-to-stand test
• The change of maximal strength of upper-limb, lower-limb and respiratory muscle
• The change of quality of life Participants in the home-based pulmonary rehabilitation group received teletechnology-assisted consultations (either by videotelephony or telephone calls) for every 1-2 weeks during the intervention period, and participants in the usual care group did not receive teletechnology-assisted consultations during the intervention period.

Conditions

COVID-19; Telerehabilitation

Keywords

Pulmonary Rehabilitation

Outcome Measures

Primary Outcomes (5)

• Six-minute walk distance

  The distance of six-minute walk test

  Week 0

• Six-minute walk distance

  The distance of six-minute walk test

  Week 4

• Six-minute walk distance

  The distance of six-minute walk test

  Week 8

• Six-minute walk distance

  The distance of six-minute walk test

  Week 12

• Six-minute walk distance

  The distance of six-minute walk test

  Week 24

Secondary Outcomes (20)

• Maximal upper limb strength

  Week 0

• Maximal upper limb strength

  Week 4

• Maximal upper limb strength

  Week 8

• Maximal upper limb strength

  Week 12

• Maximal upper limb strength

  Week 24

Study Arms (2)

Home-based pulmonary rehabilitation group

EXPERIMENTAL

The home-based pulmonary rehabilitation group received breathing exercise instructions using online learning materials soon after randomization. The participants received a home-based exercise plan, which comprised aerobic exercise and resistance exercise with instruction sheets. Teletechnology was incorporated into home-based pulmonary rehabilitation via videotelephony (or telephone calls if indicated). Time points for these teletechnology-assisted consultations were at day 7, day 14 after randomization and every 2 weeks after that until the completion of the study (week 12).

Behavioral: Teletechnology-assisted home-based pulmonary rehabilitation

Usual care group

ACTIVE COMPARATOR

The usual care group will receive breathing exercise instructions using online learning materials soon after randomization. The participants will also receive general exercise education and exercise safety principles but not any consultation about their physical activity/exercise during the study period.

Behavioral: Teletechnology-assisted home-based pulmonary rehabilitation

Interventions

Teletechnology-assisted home-based pulmonary rehabilitation BEHAVIORAL

The accuracy and safety of home-based pulmonary rehabilitation will be checked regularly through technology devices such as smart watch and via videotelephony (or telephone calls if indicated).

Home-based pulmonary rehabilitation group; Usual care group

Eligibility Criteria

• Age: 20 Years+
• Sex: all
• Healthy Volunteers: No
• Age Groups: Adult (18-64), Older Adult (65+)

You may qualify if:

• Patients are 20 years or more with severe (severe pneumonia) to critical (acute respiratory distress syndrome, sepsis, or septic shock) COVID-19 during hospitalization after deisolation.
• Patients are 65 years or more, or ever receiving oral antiviral treatment after deisolation.
• Patient have the ability to ambulate on level surface without direct contact of another person, have telecommunication device(s), and provide consent to receive teletechnology-assisted rehabilitation.

You may not qualify if:

• Patients are pregnant or planning for pregnancy.
• Patients have cognitive dysfunction, learning disability, uncontrolled arrhythmia or hypertension, or any medical diagnosis other than COVID-19 that would prominently influence their ability to follow instructions and perform exercise.

Sponsors & Collaborators

• National Taiwan University Hospital: lead

Study Sites (1)

National Taiwan University Hospital

Taipei, 100, Taiwan

Location

Related Publications (3)

• Felten-Barentsz KM, van Oorsouw R, Klooster E, Koenders N, Driehuis F, Hulzebos EHJ, van der Schaaf M, Hoogeboom TJ, van der Wees PJ. Recommendations for Hospital-Based Physical Therapists Managing Patients With COVID-19. Phys Ther. 2020 Aug 31;100(9):1444-1457. doi: 10.1093/ptj/pzaa114.

  PMID: 32556323 BACKGROUND

• Gloeckl R, Leitl D, Jarosch I, Schneeberger T, Nell C, Stenzel N, Vogelmeier CF, Kenn K, Koczulla AR. Benefits of pulmonary rehabilitation in COVID-19: a prospective observational cohort study. ERJ Open Res. 2021 May 31;7(2):00108-2021. doi: 10.1183/23120541.00108-2021. eCollection 2021 Apr.

  PMID: 34095290 BACKGROUND

• Betschart M, Rezek S, Unger I, Beyer S, Gisi D, Shannon H, Sieber C. Feasibility of an Outpatient Training Program after COVID-19. Int J Environ Res Public Health. 2021 Apr 9;18(8):3978. doi: 10.3390/ijerph18083978.

  PMID: 33918887 BACKGROUND

MeSH Terms

Conditions

COVID-19

Condition Hierarchy (Ancestors)

Pneumonia, Viral; Pneumonia; Respiratory Tract Infections; Infections; Virus Diseases; Coronavirus Infections; Coronaviridae Infections; Nidovirales Infections; RNA Virus Infections; Lung Diseases; Respiratory Tract Diseases

Study Officials

• Ping-Lun Hsieh

  National Taiwan University Hospital

  PRINCIPAL INVESTIGATOR

Study Design

• Study Type: interventional
• Phase: not applicable
• Allocation: RANDOMIZED
• Masking: SINGLE
• Who Masked: OUTCOMES ASSESSOR
• Purpose: TREATMENT
• Intervention Model: PARALLEL
• Sponsor Type: OTHER
• Responsible Party: PRINCIPAL INVESTIGATOR
• PI Title: Mr. Ping-Lun Hsieh

Study Record Dates

• First Submitted: March 13, 2023
• First Posted: March 21, 2023
• Study Start: April 12, 2023
• Primary Completion: May 24, 2024
• Study Completion: May 24, 2024
• Last Updated: September 11, 2025

Record last verified: 2025-09

Data Sharing

• IPD Sharing: Will not share

Locations

TW (1)