Trials Sponsors Conditions Drugs Pricing

Conditions

Patella; Tendinitis

Outcome Measures

Primary Outcomes (1)

Protein turnover in tendon tissue from patients with chronic tendinopathy compared to healthy controls
Fractional synthesis rate (FSR) measured in % pr. day in the trypsin-soluble and trypsin-insoluble fraction
8 days

Secondary Outcomes (9)

Tracer incorporation in isolated fractions of the tendon
8 days
Tracer incorporation in isolated fractions of the tendon
8 days
Anterior-posterior dimensions of patella tendon
8 days
Doppler flow in patella tendon
8 days
Subjective pain in patella tendon
8 days
+4 more secondary outcomes

Study Arms (2)

Chronic tendinopathy patients

EXPERIMENTAL

Other: Cross-sectional comparison between healthy and tendinopathic group

Healthy controls

EXPERIMENTAL

Other: Progressive resistance trainingOther: Cross-sectional comparison between healthy and tendinopathic group

Interventions

Progressive resistance trainingOther

Only the control group: 3 exercise bouts within the study period. Comparison between exercised and non-exercised leg.

Healthy controls

Cross-sectional comparison between healthy and tendinopathic groupOther

Comparison of primary and secondary outcomes.

Chronic tendinopathy patients

Eligibility Criteria

Age18 Years - 40 Years

Sexall

Healthy VolunteersYes

Age GroupsAdult (18-64)

You may qualify if:

Physical active men and women
Body mass index 18,5 - 30 kg/m2

Sponsors & Collaborators

Bispebjerg Hospital
Otherlead

Study Sites (1)

Institute of Sports Medicine Copenhagen

Copenhagen, Capital Region, 2400, Denmark

MeSH Terms

Conditions

Patella FractureTendinopathy

Condition Hierarchy (Ancestors)

Knee FracturesFractures, BoneWounds and InjuriesMuscular DiseasesMusculoskeletal DiseasesTendon Injuries

Study Officials

Michael Kjær, Professor
Institute of Sports Medicine, Copenhagen
PRINCIPAL INVESTIGATOR

Enrollment

36 participants (actual enrollment reported by the registry).

Study Design

Study Type: interventional
Phase: not applicable
Allocation: NON RANDOMIZED
Masking: SINGLE
Who Masked: OUTCOMES ASSESSOR
Purpose: BASIC SCIENCE
Intervention Model: PARALLEL
Sponsor Type: OTHER
Responsible Party: PRINCIPAL INVESTIGATOR
PI Title: Medical Doctor

Study Record Dates

First Submitted

March 3, 2023

First Posted

March 20, 2023

Study Start

May 10, 2023

Actual (reported)

Protein Turnover in Healthy and Overuse-diseased Tendon

Brief Summary

Registry Overview

Trial Relationships

Study Timeline

First Submitted

First Posted

Study Start

Primary Completion

Study Completion

Conditions

Outcome Measures

Primary Outcomes (1)

Secondary Outcomes (9)

Study Arms (2)

Chronic tendinopathy patients

Healthy controls

Interventions

Eligibility Criteria

You may qualify if:

Sponsors & Collaborators

Study Sites (1)

MeSH Terms

Conditions

Condition Hierarchy (Ancestors)

Study Officials

Enrollment

Study Design

Study Record Dates

You may not qualify if:

Data Sharing

Source record

Locations

Brief Summary

Registry Overview

Trial Relationships

Related Scientific Literature

Study Timeline

First Submitted

First Posted

Study Start

Primary Completion

Study Completion

Conditions

Outcome Measures

Primary Outcomes (1)

Secondary Outcomes (9)

Study Arms (2)

Chronic tendinopathy patients

Healthy controls

Interventions

Eligibility Criteria

You may qualify if:

Sponsors & Collaborators

Study Sites (1)

MeSH Terms

Conditions

Condition Hierarchy (Ancestors)

Study Officials

Enrollment

Study Design

Study Record Dates

You may not qualify if:

Data Sharing

Source record

Locations