Blood Glucose Management in Intensive Care Units

NCT05775770 | Unknown

• 1 other identifier: 2022-A01304-39
• Study Type: observational
• Target: 525
• Locations: 1 country
• Sites: 1

Brief Summary

The investigators propose to conduct a study of practices to describe the methods of managing glycemic control in hospitalized patients in critical care. This is a prospective multicenter observational study conducted in Intensive Medicine and Resuscitation departments in France and Belgium. The aim of this study is to carry out an inventory of the current practices of glycemia management as well as their modalities. Being one of the key points of the management, this work will have for main objective to raise the importance of the glycemic variabilities according to the methods of insulin therapies used.

Conditions

Insulin Hypoglycemia; Glucose Test Site Bleeding; Hyperglycemia

Keywords

glucose control; insulin

Outcome Measures

Primary Outcomes (1)

• glycemic variability

  Study the impact of glycemic management protocols on the glycemic variability of patients hospitalized in intensive care

  48 hours

Secondary Outcomes (2)

• adverse outcomes

  48 hours

• Analysis of nursing workload

  48 hours

Interventions

Insulin DRUG

insulin therapy

Eligibility Criteria

• Age: 18 Years+
• Sex: all
• Healthy Volunteers: No
• Age Groups: Adult (18-64), Older Adult (65+)
• Sampling Method: Probability Sample

Study Population

All adult patients admitted to intensive care or intensive care.

You may qualify if:

• Patient with hyperglycaemia requiring an insulin prescription within 48 hours of admission
• Expected duration of hospitalization greater than or equal to 48 hours

You may not qualify if:

• Moribund patients
• Patients admitted for ketoacidosis or hyperosmolar coma
• Patients admitted for symptomatic hypoglycaemia
• Patient requiring insulin for serum potassium correction
• Severe acute hepatocellular insufficiency
• Age \< 18 years old
• Pregnant or breastfeeding women
• Patients under legal protection measures

Sponsors & Collaborators

• French Society for Intensive Care: lead

Study Sites (1)

CHU Caen

Caen, France

RECRUITING

MeSH Terms

Conditions

Hyperglycemia; Insulin Resistance

Interventions

Insulin

Condition Hierarchy (Ancestors)

Glucose Metabolism Disorders; Metabolic Diseases; Nutritional and Metabolic Diseases; Hyperinsulinism

Intervention Hierarchy (Ancestors)

Proinsulin; Insulins; Pancreatic Hormones; Peptide Hormones; Hormones; Hormones, Hormone Substitutes, and Hormone Antagonists; Peptides; Amino Acids, Peptides, and Proteins

Study Officials

• Laurent Papazian

  French Society for Intensive Care

  STUDY DIRECTOR

Central Study Contacts

Suzanne Goursaud

CONTACT

1 45 86 74 00; goursaud-s@chu-caen.fr

Laurent Poiroux

CONTACT

LaPoiroux@chu-angers.fr

Study Design

• Study Type: observational
• Observational Model: COHORT
• Time Perspective: PROSPECTIVE
• Sponsor Type: OTHER
• Responsible Party: SPONSOR

Study Record Dates

• First Submitted: March 7, 2023
• First Posted: March 20, 2023
• Study Start: March 20, 2023
• Primary Completion: March 12, 2024
• Study Completion: March 12, 2024
• Last Updated: April 6, 2023

Record last verified: 2023-03

Locations

FR (1)