NCT05772325

Brief Summary

A randomized controlled study comparing brief dietary intervention with a personal, tailored dietary advice (60 min) on change in LDL-c and change in diet.

Trial Health

43
At Risk

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Trial has exceeded expected completion date
Enrollment
70

participants targeted

Target at P25-P50 for not_applicable rheumatoid-arthritis

Timeline
Completed

Started Feb 2023

Geographic Reach
1 country

1 active site

Status
unknown

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

Click on a node to explore related trials.

Study Timeline

Key milestones and dates

Study Start

First participant enrolled

February 20, 2023

Completed
14 days until next milestone

First Submitted

Initial submission to the registry

March 6, 2023

Completed
10 days until next milestone

First Posted

Study publicly available on registry

March 16, 2023

Completed
1.5 years until next milestone

Primary Completion

Last participant's last visit for primary outcome

August 31, 2024

Completed
Same day until next milestone

Study Completion

Last participant's last visit for all outcomes

August 31, 2024

Completed
Last Updated

March 20, 2023

Status Verified

March 1, 2023

Enrollment Period

1.5 years

First QC Date

March 6, 2023

Last Update Submit

March 17, 2023

Conditions

Outcome Measures

Primary Outcomes (1)

  • LDL cholesterol change from baseline

    LDL cholesterol change from baseline

    8 weeks

Secondary Outcomes (1)

  • Change in Healthy Diet Score (HDS) according to SmartDiet score

    8 weeks

Study Arms (2)

Brief standardized dietary advice

ACTIVE COMPARATOR

The brief standardized 4-minute heart healthy dietary advice will be provided by an experienced cardiologist or rheumatologists.

Other: The brief standardized 4-minute heart healthy dietary advice

Individually tailored diet counseling

EXPERIMENTAL

Participants in the intervention group will receive a 60 min individually tailored heart-friendly diet consultation by a dietitian.

Other: Individually tailored diet counseling

Interventions

Participants in the intervention group will receive a 60 min individually tailored heart-friendly diet consultation by a dietitian

Individually tailored diet counseling

The brief standardized 4-minute heart healthy dietary advice will be provided by an experienced cardiologist or rheumatologists

Brief standardized dietary advice

Eligibility Criteria

Age30 Years - 80 Years
Sexall
Healthy VolunteersYes
Age GroupsAdult (18-64), Older Adult (65+)

You may qualify if:

  • Patients with either RA, PsA, or AS, between 30-80 years with an increased risk of future CVD, estimated using the CVD risk calculator. i.e. any risk \> 5 -10 % predicted by Systematic Coronary Risk Evaluation (SCORE2) algorithm. Also, patients with very high risk (predicted risk \>10%) as well as established atherosclerotic CVD (ASCVD) including previous myocardial infarction, coronary intervention (coronary artery bypass grafting or percutaneous coronary intervention), transient ischemic attack/strokes, atherosclerotic diseases of arteries as in the carotid artery or peripheral arterial disease (PAD) will also be included.

You may not qualify if:

  • Heart failure with systolic EF\<40%
  • Kidney failure with GFR \< 35
  • Liver failure
  • Mental disorder rendering the patient unable to comply with the protocol
  • Being able to speak the language of the country
  • Reduced cognitive function
  • Substance abuse

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Study Sites (1)

Diakonhjemmet Hospital

Oslo, 0370, Norway

RECRUITING

MeSH Terms

Conditions

Arthritis, RheumatoidArthritis, PsoriaticSpondylarthritis

Condition Hierarchy (Ancestors)

ArthritisJoint DiseasesMusculoskeletal DiseasesRheumatic DiseasesConnective Tissue DiseasesSkin and Connective Tissue DiseasesAutoimmune DiseasesImmune System DiseasesSpondylarthropathiesSpondylitisSpinal DiseasesBone DiseasesPsoriasisSkin Diseases, PapulosquamousSkin Diseases

Central Study Contacts

Anne Grete Semb, MD, PhD

CONTACT

Study Design

Study Type
interventional
Phase
not applicable
Allocation
RANDOMIZED
Masking
SINGLE
Who Masked
OUTCOMES ASSESSOR
Purpose
PREVENTION
Intervention Model
PARALLEL
Sponsor Type
OTHER
Responsible Party
SPONSOR

Study Record Dates

First Submitted

March 6, 2023

First Posted

March 16, 2023

Study Start

February 20, 2023

Primary Completion

August 31, 2024

Study Completion

August 31, 2024

Last Updated

March 20, 2023

Record last verified: 2023-03

Data Sharing

IPD Sharing
Will not share

Locations