Central London Patient Safety Research Collaboration

NCT05772195 | Active Not Recruiting DMC

• 1 other identifier: NIHR204297
• Study Type: observational
• Target: 500,000
• Locations: 1 country
• Sites: 1

Brief Summary

Patient safety is a priority for healthcare systems. In safe systems, patients would be saved from avoidable harm, both from their own conditions, and from the care and treatments provided to them. Amongst the highest risk clinical settings are Surgical, Perioperative, Acute and Critical carE services (SPACE). The Central London Patient Safety Research Collaborative is funded to deliver world-class research into improving the safety of SPACE services, within which the investigators will evaluate major service reorganisation, compare and investigate organisational safety and quality, and investigate the disparity in postoperative complications associated with socioeconomic factors.

Conditions

Surgery-Complications; Safety Issues

Outcome Measures

Primary Outcomes (3)

• Total number of elective operations performed within the NHS

  Process and outcomes following major system change (Theme 1): To be presented and analysed 1. nationally, 2. regionally and 3. at hospital Trust- level To assess the effectiveness of the NHS Elective recovery plan (https://www.england.nhs.uk/2022/02/nhs-publishes-electives-recovery-plan-to-boost-capacity-and-give-power-to-patients/)

  8 years (2017/18 - 2024/25) as per cohort definitions

• Incidence/prevalence of postoperative complications

  Process and outcomes following major system change (Theme 1): Postoperative complications. * Occurring whilst inpatient, following the index surgical procedure. * Classified using the Clavien-Dindo and Postoperative Morbidity Survey systems * We will gather and link data from national audit and registry datasets. * We will compare patient outcomes within and between organisations to investigate safety and quality

  Pre 2023

• Incidence/prevalence of postoperative complications stratified by socioeconomic and ethnic descriptors

  Theme 3 safer innovations: Postoperative complications. * Occurring whilst inpatient, following the index surgical procedure. * Classified using the Clavien-Dindo and Postoperative Morbidity Survey systems * We will gather and link data from national audit and registry datasets. * We will investigate divergences in patient outcomes, stratified by socioeconomic and ethnic descriptors

  Pre 2023

Secondary Outcomes (2)

• Mean/median postoperative length of stay (days)

  8 years (2017/18 - 2024/25) as per cohort definitions

• Mean/Median postoperative critical care length of stay (days)

  8 years (2017/18 - 2024/25) as per cohort definitions

Study Arms (3)

Before major system reorganisation

Theme 1 - elective recovery plan 2017/18-2019/20

Before major system reorganisation - intra-pandemic

Theme 1 - elective recovery plan 2020/21-2021/22

Post system reorganisation

Theme 1 - elective recovery plan 2023/24 and 2024/25

Eligibility Criteria

• Age: 18 Years+
• Sex: all
• Age Groups: Adult (18-64), Older Adult (65+)
• Sampling Method: Non-Probability Sample

Study Population

Major surgery Critical care admission

You may qualify if:

• as determined by clinical audits

You may not qualify if:

• missing key data items/ or linkage

Sponsors & Collaborators

• University College London Hospitals: lead

Study Sites (1)

University College London

London, United Kingdom

Location

Study Design

• Study Type: observational
• Observational Model: COHORT
• Time Perspective: RETROSPECTIVE
• Sponsor Type: OTHER
• Responsible Party: PRINCIPAL INVESTIGATOR
• PI Title: Associate Professor

Study Record Dates

• First Submitted: January 5, 2023
• First Posted: March 16, 2023
• Study Start: April 3, 2023
• Primary Completion: April 1, 2025
• Study Completion: April 1, 2026
• Last Updated: May 22, 2023

Record last verified: 2023-05

Locations

GB (1)