SB and Cardiac Function and Structure in IHD

NCT05771610 | Unknown

• 1 other identifier: SB and IHD
• Study Type: observational
• Target: 67
• Locations: 0 countries
• Sites: N/A

Brief Summary

Cardiovascular Disease (CVD) is the leading cause of mortality and morbidity globally. Following a myocardial infarction (MI), an individual is at an increased risk of a secondary event (20-50% higher risk post MI), compared to those with no prior CVD. Independent of physical activity levels, high amounts of daily sitting is a risk factor for CVD, of which sitting is typically used as an indicator for sedentary behaviour. Sedentary behaviour is defined as a waking energy expenditure of less than 1.5 METs (metabolic task equivalent) while in a seated, reclined or lying posture. Currently, there is little knowledge regarding the prevalence of sedentary behaviour ischaemic heart disease. The aim of this study is therefore to measure activity levels of an individual following a diagnosis of ischaemic heart disease, alongside its association to cardiac function and cardiovascular risk factors. Sitting patterns and physical activity will be monitored 24 h/day during each condition using an activPAL activity monitor (PAL Technologies, Glasco, Scotland). This will measure changes in posture and level of activity by cadence.

Conditions

Cardiovascular Diseases; Sedentary Behavior

Outcome Measures

Primary Outcomes (1)

• Daily sitting time in IHD

  Measured using activpal

  7 days

Secondary Outcomes (20)

• Posterior wall thickness

  9 months

• Intraventricular septum

  9 months

• Left ventricular internal diameter

  9 months

• Aortic root

  9 months

• End volume

  9 months

Interventions

Activity pattern in CVD BEHAVIORAL

Only individuals who have had a cardiac event within the past twelve months upon recruitment will be included in this study.

Eligibility Criteria

• Age: 18 Years+
• Sex: all
• Age Groups: Adult (18-64), Older Adult (65+)
• Sampling Method: Non-Probability Sample

Study Population

ischaemic heart disease, including a myocardial infarction within the past twelve months ((NSTEMI or STEMI) confirmed by blood markers or electrophysiological changes); or angina treated with PCI or CABG.

You may qualify if:

• · Patients diagnosed with ischemic heart disease within the past 12 months (within National Audit of Cardiac Rehabilitation (NACR) outcome data). This includes post myocardial infarction (ST wave elevated MI or Non-ST wave elevated MI), post coronary artery bypass graft, post percutaneous coronary intervention.
• Males and females
• Aged 18 years or above.
• Any ethnicity.

You may not qualify if:

• · Under 18 years of age.
• Unable to provide valid informed consent (lack of mental capacity).
• Not had a cardiac event diagnosed within the past 12 months.
• Unstable coronary disease.
• Disease or conditions with a prognosis of less than 6 months to end of life (palliative care).

Sponsors & Collaborators

• University of Bedfordshire: lead

MeSH Terms

Conditions

Cardiovascular Diseases; Sedentary Behavior

Condition Hierarchy (Ancestors)

Behavior

Study Design

• Study Type: observational
• Observational Model: COHORT
• Time Perspective: PROSPECTIVE
• Sponsor Type: OTHER
• Responsible Party: PRINCIPAL INVESTIGATOR
• PI Title: Principal Investigator

Study Record Dates

• First Submitted: March 2, 2023
• First Posted: March 16, 2023
• Study Start: March 6, 2023
• Primary Completion: December 1, 2023
• Study Completion: December 31, 2023
• Last Updated: March 16, 2023

Record last verified: 2023-03

Data Sharing

• IPD Sharing: Will not share