Craniofacial Morphology And Sella Turcica Bridging Associated With Third Molar Agenesis.

NCT05771246 | Completed

• 1 other identifier: 2023-AGENESISTHIRDMOLAR
• Study Type: observational
• Target: 400
• Locations: 1 country
• Sites: 1

Brief Summary

The aim of this retrospective study is to analyze the third molar agenesis with respect to sella turcica bridging and other craniofacial patterns in patients asking for orthodontic consultation. The main question\[s\] it aims to answer are:

• is there a relationship between third molar agenesis and sella turchina bridging?
• is there a relationship between third molar agenesis and craniofacial patterns?

Conditions

Tooth Agenesis

Outcome Measures

Primary Outcomes (6)

• Linear regression between third molar agenesis and ANB

  ANB is calculated according to Riedel's analysis: angle formed between Point A (maxillary sovraspinal point), point B (Bubmental mandibular point) and N (Nasion)

  Baseline

• Linear regression between third molar agenesis and Interclinoid Distance

  Distance between tuberculum sella (TS) and dorsum sella (DS).

  Baseline

• Linear regression between third molar agenesis and Sella Depth.

  Distance of a line dropped perpendicular from the interclinoid distance to the deepest point of the sella floor.

  Baseline

• Linear regression between third molar agenesis and Sella Diameter

  Distance between tuberculum sella and the farthest point on the inner wall of the sella.

  Baseline

• Linear regression between third molar agenesis and Sn^GoGn.

  Steiner's Sn\^GoGn is the angle formed between 2 planes: cranial base line (SN) and mandibular plane (GoGn)

  Baseline

• Linear regression between third molar agenesis and ArGo^GoGn

  Jaraback's Ar\^Go\^Gn is the angle formed between the 2 planes: ArGo and GoGn

  Baseline

Study Arms (2)

Case group

Patients with third molar agenesis.

Diagnostic Test: Radiographic evaluation

Control group

Patients with the presence of all third molars.

Diagnostic Test: Radiographic evaluation

Interventions

Radiographic evaluation DIAGNOSTIC_TEST

Panoramic and lateral cephalometric radiographs with cephalometric analysis will be performed.

Case group; Control group

Eligibility Criteria

• Age: 8 Years - 18 Years
• Sex: all
• Healthy Volunteers: No
• Age Groups: Child (0-17), Adult (18-64)
• Sampling Method: Non-Probability Sample

Study Population

Patients referring to the Unit of Orthodontics and Pediatric Dentistry for orthodontic consultation.

You may qualify if:

• G stage of Demirjian's classification for third molar maturation or absence of third molar germs
• Patients with one lateral cephalometric digital radiograph executed in Natural Head Position (patients were asked to keep the teeth in contact and the lips relaxed).
• Patients with panoramic radiograph;

You may not qualify if:

• Ascertained previous surgical extraction/s of third molar/s
• Orthopedic/orthodontic therapy
• Orthognathic surgery.

Sponsors & Collaborators

• University of Pavia: lead

Study Sites (1)

Unit of Orthodontics and Pediatric Dentistry - Section of Dentistry - Department of Clinical, Surgical, Diagnostic and Pediatrics - University of Pavia

Pavia, Lombardy, 27100, Italy

Location

MeSH Terms

Conditions

Anodontia

Condition Hierarchy (Ancestors)

Tooth Abnormalities; Stomatognathic System Abnormalities; Stomatognathic Diseases; Tooth Diseases; Congenital Abnormalities; Congenital, Hereditary, and Neonatal Diseases and Abnormalities

Study Officials

• Andrea Scribante, DDS, Ms, PhD

  University of Pavia

  PRINCIPAL INVESTIGATOR

Study Design

• Study Type: observational
• Observational Model: CASE CONTROL
• Time Perspective: RETROSPECTIVE
• Sponsor Type: OTHER
• Responsible Party: PRINCIPAL INVESTIGATOR
• PI Title: Associate Professor, Principal Investigator

Study Record Dates

• First Submitted: February 17, 2023
• First Posted: March 16, 2023
• Study Start: March 6, 2023
• Primary Completion: June 1, 2023
• Study Completion: June 7, 2023
• Last Updated: July 9, 2024

Record last verified: 2024-07

Data Sharing

• IPD Sharing: Will not share

Locations

IT (1)