NCT05757739

Brief Summary

Lateral epicondylitis (Tennis Elbow) can cause pain and keep individuals from completing their daily activities and require them to miss work. There are currently different treatment options to address tennis elbow. However surgeons do not know if one is better than the other. This study will compare two treatment options for tennis elbow. Participants will either be treated by Ultrasound-guided Percutaneous Tenotomy Technique or Open Surgical Debridement. Traditional open surgical debridement is a surgical procedure that requires the surgeon to make an incision to remove the damaged tissue. This procedure is done under anesthesia in a surgery center. In the Tenex procedure, the surgeon inserts a special needle into the damaged portion of the tendon under ultrasound guidance. Ultrasonic energy vibrates the damaged tissue and it can be suctioned out. This procedure is done with local anesthesia in surgeon's office.

Trial Health

77
On Track

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Enrollment
90

participants targeted

Target at P50-P75 for all trials

Timeline
1mo left

Started Feb 2023

Typical duration for all trials

Geographic Reach
1 country

5 active sites

Status
recruiting

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

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Study Timeline

Key milestones and dates

Study Progress98%
Feb 2023Jun 2026

Study Start

First participant enrolled

February 9, 2023

Completed
14 days until next milestone

First Submitted

Initial submission to the registry

February 23, 2023

Completed
12 days until next milestone

First Posted

Study publicly available on registry

March 7, 2023

Completed
2.7 years until next milestone

Primary Completion

Last participant's last visit for primary outcome

December 1, 2025

Completed
6 months until next milestone

Study Completion

Last participant's last visit for all outcomes

June 1, 2026

Expected
Last Updated

January 22, 2025

Status Verified

January 1, 2025

Enrollment Period

2.8 years

First QC Date

February 23, 2023

Last Update Submit

January 17, 2025

Conditions

Outcome Measures

Primary Outcomes (1)

  • Background: Ultrasound-guided Percutaneous Tenotomy Technique

    Background: Ultrasound-guided Percutaneous Tenotomy Technique

    3 months

Interventions

TenexPROCEDURE

In the Tenex procedure, the surgeon inserts a special needle into the damaged portion of the tendon under ultrasound guidance. Ultrasonic energy vibrates the damaged tissue and it can be suctioned out. This procedure is done with local anesthesia in surgeon's office.

Eligibility Criteria

Age19 Years - 70 Years
Sexall
Healthy VolunteersYes
Age GroupsAdult (18-64), Older Adult (65+)
Sampling MethodProbability Sample
Study Population

Patients with clinically documented chronic lateral epicondylitis with a minimum of 6 months of persistent elbow pain that impedes daily activities.

You may qualify if:

  • Individuals 18-70 years of age
  • Clinically documented chronic lateral epicondylitis with a minimum of 6 months of persistent elbow pain that impedes daily activities.
  • Failed alternative treatment for \> 3 months.

You may not qualify if:

  • Surgical procedure on affected extremity within last six months.
  • Dermatological disorder in affected area
  • Currently pregnant, confirmed via pregnancy test.
  • Blood disorders, autoimmune disorders, disorders requiring immunosuppression, cancer, malignancies, an ongoing infectious disease, or sickle cell or other blood disorders.
  • Failed prior surgical procedure on the affected joint.
  • No prior effort to treat (stretching, rest, medication) or implementation of external protocol in an effort to improve condition (physical therapy, massage treatment, rehabilitation techniques).

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Study Sites (5)

Virtua Health Inc

Burlington, New Jersey, 08016, United States

RECRUITING

Virtua Health and Wellness

Cherry Hill, New Jersey, 08033, United States

RECRUITING

Virtua Cadiac Testing Center

Moorestown, New Jersey, 08057-3128, United States

RECRUITING

Virtua Hand Surgery

Riverside Park, New Jersey, 08075, United States

RECRUITING

Summit Surgical Center LLC

Voorhees Township, New Jersey, 08043, United States

RECRUITING

MeSH Terms

Interventions

Guanfacine

Intervention Hierarchy (Ancestors)

GuanidinesAmidinesOrganic ChemicalsPhenylacetatesAcids, CarbocyclicCarboxylic Acids

Central Study Contacts

Study Design

Study Type
observational
Observational Model
OTHER
Time Perspective
PROSPECTIVE
Sponsor Type
OTHER
Responsible Party
SPONSOR

Study Record Dates

First Submitted

February 23, 2023

First Posted

March 7, 2023

Study Start

February 9, 2023

Primary Completion

December 1, 2025

Study Completion (Estimated)

June 1, 2026

Last Updated

January 22, 2025

Record last verified: 2025-01

Locations