NCT05741892

Brief Summary

The aim of the study is to assess the accuracy of fracture reduction performed with surgical guides designed and 3D printed at the point of care in comminuted fractures of femur- and tibia-shaft.

Trial Health

43
At Risk

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Trial has exceeded expected completion date
Enrollment
15

participants targeted

Target at below P25 for not_applicable

Timeline
Completed

Started Apr 2023

Typical duration for not_applicable

Geographic Reach
1 country

1 active site

Status
unknown

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

Click on a node to explore related trials.

Study Timeline

Key milestones and dates

First Submitted

Initial submission to the registry

February 13, 2023

Completed
10 days until next milestone

First Posted

Study publicly available on registry

February 23, 2023

Completed
1 month until next milestone

Study Start

First participant enrolled

April 1, 2023

Completed
1.7 years until next milestone

Primary Completion

Last participant's last visit for primary outcome

December 1, 2024

Completed
1 year until next milestone

Study Completion

Last participant's last visit for all outcomes

December 1, 2025

Completed
Last Updated

December 6, 2023

Status Verified

December 1, 2023

Enrollment Period

1.7 years

First QC Date

February 13, 2023

Last Update Submit

December 5, 2023

Conditions

Keywords

FemurTibiaComminuted fracture3D printingpersonalized medicine

Outcome Measures

Primary Outcomes (1)

  • Rotational deviation (Axial plane deviation) in degree

    Planned rotational alignment versus postoperative rotational alignment.

    Between 1 to 7 days postoperative, depending on the patients status

Secondary Outcomes (3)

  • Length deviation in mm

    Between 1 to 7 days postoperative, depending on the patients status

  • Frontal plane deviation in degree

    Between 1 to 7 days postoperative, depending on the patients status

  • Sagittal plane deviation in degree

    Between 1 to 7 days postoperative, depending on the patients status

Study Arms (1)

3D fracture reposition guide group

EXPERIMENTAL

Comminuted tibial- or/and femur shaft fractures will be treated using 3D printed patient-specific repositions guides.

Device: Fracture reposition with 3D printed patient specific repositions guides

Interventions

Comminuted tibial- or/and femur shaft fractures will be treated using 3D printed patient-specific repositions guides.

3D fracture reposition guide group

Eligibility Criteria

Age18 Years - 99 Years
Sexall
Healthy VolunteersNo
Age GroupsAdult (18-64), Older Adult (65+)

You may qualify if:

  • Age between 18 and 99 years
  • Comminuted shaft fracture of tibia or femur
  • Intact contralateral tibia or femur
  • Patient willing to participate and sign the informed consent
  • Clear indication of surgical treatment

You may not qualify if:

  • Refusal to sign the informed consent
  • Abnormal contralateral bony anatomy (previous surgeries, poliomyelitis, previous injury, implants)
  • Pregnancy
  • Acute tumor or previous tumor disease
  • Acute infection

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Study Sites (1)

Universitätsklinik für Orthopädische Chirurgie und Traumatologie

Bern, 3010, Switzerland

RECRUITING

MeSH Terms

Conditions

Tibial FracturesFemoral FracturesFractures, Comminuted

Condition Hierarchy (Ancestors)

Fractures, BoneWounds and InjuriesLeg Injuries

Study Officials

  • Hecker Andreas, MD

    Universitätsklinik für Orthopädische Chirurgie und Traumatologie

    PRINCIPAL INVESTIGATOR

Central Study Contacts

Hecker Andreas, MD

CONTACT

Hess Silvan, MD

CONTACT

Study Design

Study Type
interventional
Phase
not applicable
Allocation
NA
Masking
NONE
Purpose
TREATMENT
Intervention Model
SINGLE GROUP
Model Details: Prospective case series
Sponsor Type
OTHER
Responsible Party
SPONSOR

Study Record Dates

First Submitted

February 13, 2023

First Posted

February 23, 2023

Study Start

April 1, 2023

Primary Completion

December 1, 2024

Study Completion

December 1, 2025

Last Updated

December 6, 2023

Record last verified: 2023-12

Data Sharing

IPD Sharing
Will not share

Locations