NCT05741554

Brief Summary

Investigators studied a population of 28 low grade serous ovarian carcinoma treated in Hospices civils de Lyon between 2000 and 2022. The primary objective is to determinate the rate of myometrial involvement by the cancer at pathology examination. Then, investigators compared patients with or without myometrial involvement : survival parameters, predictive factors of myometrial involvement (age, CA 125 level, surgery characteristics, pathology characteristics).

Trial Health

87
On Track

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Enrollment
28

participants targeted

Target at below P25 for all trials

Timeline
Completed

Started Sep 2021

Geographic Reach
1 country

1 active site

Status
completed

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

Click on a node to explore related trials.

Study Timeline

Key milestones and dates

Study Start

First participant enrolled

September 1, 2021

Completed
9 months until next milestone

Primary Completion

Last participant's last visit for primary outcome

June 1, 2022

Completed
4 months until next milestone

Study Completion

Last participant's last visit for all outcomes

October 10, 2022

Completed
4 months until next milestone

First Submitted

Initial submission to the registry

February 14, 2023

Completed
9 days until next milestone

First Posted

Study publicly available on registry

February 23, 2023

Completed
Last Updated

February 23, 2023

Status Verified

February 1, 2023

Enrollment Period

9 months

First QC Date

February 14, 2023

Last Update Submit

February 14, 2023

Conditions

Serous Ovarian CarcinomaLow Grade Serous Ovarian Carcinoma

Keywords

Serous ovarian carcinomaLow grade serous ovarian carcinomaFertility sparring surgeryHysterectomy

Outcome Measures

Primary Outcomes (1)

  • Percentage of myometrial involvement

    Myometrial involvement after pathology examination

    After pathology examination, average 2 to 3 weeks after cytoreductive surgery

Study Arms (2)

Myometrial involvement

Myometrial involvement by cancer metastasis after pathology examination

Other: Rate of myometrial involvement in the population of 28 low grade serous ovarian carcinoma.

No myometrial involvement

Absence of myometrial involvement by cancer metastasis after pathology examination

Other: Rate of myometrial involvement in the population of 28 low grade serous ovarian carcinoma.

Interventions

Rate of myometrial involvement in the population of 28 low grade serous ovarian carcinoma.OTHER

Presence of uterine myometrial metastasis at pathology examination after cytoreductive surgery

Myometrial involvementNo myometrial involvement

Eligibility Criteria

Sexfemale(Gender-based eligibility)
Age GroupsChild (0-17), Adult (18-64), Older Adult (65+)
Sampling MethodNon-Probability Sample
Study Population

All patients treated in hospices Civils de Lyon for a Low grade serous ovarian cancer between January 2000 and May 2022

You may qualify if:

  • years old or more
  • low grade serous ovarian cancer (MDACC classification)
  • Grade 1 serous ovarian carcinoma (Silverberg classification)

You may not qualify if:

  • no sufficient data available
  • grade 2 and 3 serous ovarian carcinoma

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Study Sites (1)

Hospices civils de Lyon

Lyon, 69000, France

Location

Study Design

Study Type
observational
Observational Model
COHORT
Time Perspective
RETROSPECTIVE
Sponsor Type
OTHER
Responsible Party
SPONSOR

Study Record Dates

First Submitted

February 14, 2023

First Posted

February 23, 2023

Study Start

September 1, 2021

Primary Completion

June 1, 2022

Study Completion

October 10, 2022

Last Updated

February 23, 2023

Record last verified: 2023-02

Locations

FR(1)