Deprescribing and Health-related Effects

NCT05721534 | Completed

• 1 other identifier: K2023-008
• Study Type: observational
• Target: 87
• Locations: 1 country
• Sites: 1

Brief Summary

In a primary care settled quality improvement project aiming to deprescribe medication through a medication review intervention, we investigated how the implemented medication changes affected health-related outcomes in real-life patients.

Conditions

Chronic Disease

Keywords

Primary care; Medication review; Deprescribing; Polypharmacy; Chronic disease management

Outcome Measures

Primary Outcomes (1)

• self-reported health status

  (on a scale from 1 to 10)

  4 months

Secondary Outcomes (2)

• general condition

  4 months

• functional level

  4 months

Study Arms (2)

Care home residents

The intervention was offered to new residents and residents that had not yet attended a consultation focusing on pharmacological treatment in The Chronic Care Model.

Other: Medication review

Community-dwelling patients with chronic disease

Patients were invited for the consultation focusing on pharmacological treatment in the month of their birthday and, thereby, included randomly and consecutively throughout the study period.

Other: Medication review

Interventions

Medication review OTHER

Annual consultation focusing on pharmacological treatment. This specific consultation constituted the "intervention". It included a structured review of the patient's health state, in addition to a structured medication review with a focus on appropriate medication and deprescribing.

Also known as: Medication review with focus on deprescribing

Care home residents; Community-dwelling patients with chronic disease

Eligibility Criteria

• Age: 50 Years - 105 Years
• Sex: all
• Age Groups: Adult (18-64), Older Adult (65+)
• Sampling Method: Probability Sample

Study Population

The study included care home residents living in selected care homes, in which the GPF was associated "care home doctors", and community-dwelling patients with chronic disease listed with the GPF.

You may qualify if:

• new residents and residents that had not yet attended a consultation focusing on pharmacological treatment in The Chronic Care Model.
• patients were invited for the consultation focusing on pharmacological treatment in the month of their birthday and, thereby, included randomly and consecutively throughout the study period.

You may not qualify if:

• unable to collaborate on follow-up questionnaires

Sponsors & Collaborators

• Anne Estrup Olesen: lead
• Frederikshavn Kommune, Frederikshavn, Denmark: collaborator
• Lægeklinikken Frederikshavn, Frederikshavn, Denmark: collaborator

Study Sites (1)

Aalborg University Hospital

Aalborg, 9000, Denmark

Location

MeSH Terms

Conditions

Chronic Disease

Interventions

Medication Review

Condition Hierarchy (Ancestors)

Disease Attributes; Pathologic Processes; Pathological Conditions, Signs and Symptoms

Intervention Hierarchy (Ancestors)

Medication Systems; Organization and Administration; Health Services Administration; Patient Care Management

Study Officials

• Anne E Olesen

  Professor

  STUDY CHAIR

Study Design

• Study Type: observational
• Observational Model: CASE ONLY
• Time Perspective: PROSPECTIVE
• Target Duration: 4 Months
• Sponsor Type: OTHER
• Responsible Party: SPONSOR INVESTIGATOR
• PI Title: Professor

Study Record Dates

• First Submitted: February 1, 2023
• First Posted: February 10, 2023
• Study Start: January 1, 2020
• Primary Completion: December 31, 2021
• Study Completion: December 31, 2022
• Last Updated: February 10, 2023

Record last verified: 2023-02

Data Sharing

• IPD Sharing: Will not share

Locations

DK (1)