Community Engagement and Conditional Incentives to Accelerate Polio

NCT05721274 | Completed

• 1 other identifier: 2022-7125-20666
• Study Type: interventional
• Target: 840
• Locations: 1 country
• Sites: 1

Brief Summary

Immunization is one of the most cost-effective and successful public health strategy in reducing the health, economic and societal burden of many infectious diseases. Pakistan and Afghanistan remain the only countries where polio is endemic, and Pakistan reports the most cases in the world. Although the rate is lower than in previous years, the situation remains alarming. This study objective is to decrease polio vaccine refusals and zero-dose vaccines by motivating behaviour change

Conditions

Polio; Immunization; Infection; Incentives

Keywords

Community engagment; Theory of change

Outcome Measures

Primary Outcomes (3)

• Vaccine refusals

  Number of polio vaccine refusals in polio campaign

  at 9 months

• Fully Immunized Children

  This would be children who are fully vaccinated appropriate to the age

  at 9 months

• IPV coverage

  this would be injectable polio vaccine coverage in children below five years of age

  at 9 months

Study Arms (2)

Intervention

EXPERIMENTAL

The study will adopt a pretest/post-test quasi-experimental design. The approach of the proposed project is to implement a participatory community engagement and demand creation strategy with trust-building community mobilization and a conditional community-based incentive scheme to reduce the refusals to vaccination and improve polio immunization coverage in intervention UCs. Clusters will be formed on a population of 1500-2000 in each intervention UC. Committees would be formed with approximately 5-7 prominent members of the community. Intervention Non-cash, incentives would be given and decided with consensus by UC committees and aim to improve infrastructure linked to health including water and sanitation and toilets in the community.

Behavioral: Community mobilization and Conditional community incentives

Control arm

NO INTERVENTION

This would be the standard of care

Interventions

Community mobilization and Conditional community incentives BEHAVIORAL

Non-cash, incentives would be given to clusters which improve the polio vaccine coverage and reduce the refusals and these incentives would be decided with consensus by community and costs would be shared

Intervention

Eligibility Criteria

• Age: 1 Day - 59 Months
• Sex: all
• Healthy Volunteers: Yes
• Age Groups: Child (0-17)

You may qualify if:

• Household with at least one child 0-59 months of age

You may not qualify if:

• Thise not willing to participate in study

Sponsors & Collaborators

• Aga Khan University: lead

Study Sites (1)

Jai Das

Karachi, Sindh, 74800, Pakistan

Location

Related Publications (1)

• Das JK, Khan A, Tabassum F, Padhani ZA, Habib A, Mirani M, Rahman AR, Khan ZA, Rizvi A, Ahmed I, Bhutta Z. The Last Mile-Community Engagement and Conditional Incentives to Accelerate Polio Eradication in Pakistan: Study Protocol for a Quasi-Experimental Trial. Methods Protoc. 2023 Sep 8;6(5):83. doi: 10.3390/mps6050083.

  PMID: 37736966 DERIVED

MeSH Terms

Conditions

Poliomyelitis; Infections

Condition Hierarchy (Ancestors)

Myelitis; Central Nervous System Infections; Enterovirus Infections; Picornaviridae Infections; RNA Virus Infections; Virus Diseases; Central Nervous System Diseases; Nervous System Diseases; Spinal Cord Diseases; Neuroinflammatory Diseases; Neuromuscular Diseases

Study Design

• Study Type: interventional
• Phase: not applicable
• Allocation: RANDOMIZED
• Masking: NONE
• Masking Details: Project team will keep liaison with key stakeholders, committee members, polio workers/supervisors and other relevant persons. Influential community members will conduct awareness and motivation activities. The messages would address reasons for OPV and routine vaccine refusals in the community and will be disseminated via health promotion materials and support groups organized by committees.
• Purpose: PREVENTION
• Intervention Model: PARALLEL
• Sponsor Type: OTHER
• Responsible Party: PRINCIPAL INVESTIGATOR
• PI Title: Assistant Professor and Assistant Director

Model Details: The intervention is based on behaviour change theory

Study Record Dates

• First Submitted: January 12, 2023
• First Posted: February 9, 2023
• Study Start: December 1, 2022
• Primary Completion: March 31, 2024
• Study Completion: March 31, 2024
• Last Updated: April 26, 2024

Record last verified: 2024-04

Locations

PA (1)