Treatment of Exertional Heatstroke witH icE wAter Soaked Towels

NCT05717777 | Active Not Recruiting

• 1 other identifier: 9805
• Study Type: observational
• Target: 55
• Locations: 1 country
• Sites: 1

Brief Summary

Exertional heat stroke (EHS) is the most serious form of heat-illness that can occur during sports and exercise. If not recognized and treated immediately mortality rate of EHS is high. Early recognition and initiation of cooling are paramount. If temperature is reduced to \< 40°C within 30 minutes of symptom onset, most patients recover completely. There are several strategies for cooling in EHS, including cooling with rotating in ice water soaked towels which cover the body of a patient. The aim of this research is to investigate the effectiveness and safety of treatment of EHS with ice water soaked towels to lower body temperature.

Conditions

Heat Stroke Exertional; Heat Illness; Heat Exhaustion

Outcome Measures

Primary Outcomes (1)

• cooling rate

  cooling rate of treatment with rotating in ice water soaked towels

  during treatment in medical facility up to 2 hours after entering the facility

Secondary Outcomes (4)

• percentage cooled to a temperature <40°C within 30 minutes

  30 minutes after entering medical facility

• Morbidity of EHS/EHE

  2 weeks and 2 months after EHS/EHE

• productivity loss (abscens of work) related to EHS and EHE

  2 months after EHS/EHE

• Posttraumatic stress symptoms after EHS and EHE

  6 months after EHS/EHE

Interventions

There is no intervention, only observational study OTHER

There is no intervention, only observational study

Eligibility Criteria

• Age: 18 Years+
• Sex: all
• Healthy Volunteers: No
• Age Groups: Adult (18-64), Older Adult (65+)
• Sampling Method: Probability Sample

Study Population

Adult runners who received medical care for EHS of EHE in the medical facility at the running events organized by Golazo Sports® at the City Pier City and Marathon Rotterdam 2023.

You may qualify if:

• In order to be eligible to participate in this study, a subject must meet all of the following criteria:
• ≥18 years
• Receive medical care at in the medical facility the City Pier City and Marathon Rotterdam 2023
• Tympanic temperature \>38.0°C

You may not qualify if:

• A potential subject who meets any of the following criteria will be excluded from participation in this study:
• Language barrier (not proficient in Dutch or English)

Sponsors & Collaborators

• Erasmus Medical Center: lead

Study Sites (1)

Erasmus MC

Rotterdam, South Holland, 3015GD, Netherlands

Location

MeSH Terms

Conditions

Heat Stress Disorders; Heat Exhaustion

Condition Hierarchy (Ancestors)

Wounds and Injuries

Study Design

• Study Type: observational
• Observational Model: COHORT
• Time Perspective: PROSPECTIVE
• Sponsor Type: OTHER
• Responsible Party: PRINCIPAL INVESTIGATOR
• PI Title: Principal Investigator, Emergency Physician, MD, PhD

Study Record Dates

• First Submitted: January 19, 2023
• First Posted: February 8, 2023
• Study Start: March 12, 2023
• Primary Completion: October 31, 2025
• Study Completion: October 31, 2025
• Last Updated: August 7, 2025

Record last verified: 2025-08

Data Sharing

• IPD Sharing: Will not share

Locations

NL (1)