NCT05714995

Brief Summary

Patients having the following gestures (blood test, change of dressing for cancerous lesion and complete toilet in bed) will be identified by the team of the medical oncology department. During the first contact (V0), the study will be presented to the patients in order to obtain their consent. Anxiety and well-being will be assessed before performing the gesture causing discomfort (gesture No.1). The gesture will then be performed and the patient's comfort will be evaluated after the gesture is performed in order to obtain the starting data for the study. Patients will be reviewed in consultation according to the time recommended for each type of gesture. During the second contact V1 (between 1 and 9 days after D0) anxiety and well-being will be assessed before performing the gesture causing discomfort (gesture No.2). Patients will then be randomized. After randomization, the first hypnosis session will be performed at the same time as gesture No. 2 and the patient's comfort will be evaluated after the gesture is performed. The patient will receive the self-hypnosis training on the same day. A period of 7 ± 2 days will be considered for the learning time of self-hypnosis. The third contact will take place on day D7+/-2 after V1. During this visit, anxiety and well-being will be assessed before performing the gesture causing discomfort (gesture No.3). Gesture No.3 will be carried out under the effect of self-hypnosis ± aromatherapy and the measurement of comfort will be carried out immediately afterwards

Trial Health

77
On Track

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Enrollment
66

participants targeted

Target at P25-P50 for all trials

Timeline
5mo left

Started Apr 2024

Typical duration for all trials

Geographic Reach
1 country

1 active site

Status
recruiting

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

Click on a node to explore related trials.

Study Timeline

Key milestones and dates

Study Progress83%
Apr 2024Oct 2026

First Submitted

Initial submission to the registry

January 12, 2023

Completed
25 days until next milestone

First Posted

Study publicly available on registry

February 6, 2023

Completed
1.2 years until next milestone

Study Start

First participant enrolled

April 10, 2024

Completed
2.5 years until next milestone

Primary Completion

Last participant's last visit for primary outcome

October 10, 2026

Expected
Same day until next milestone

Study Completion

Last participant's last visit for all outcomes

October 10, 2026

Last Updated

March 11, 2026

Status Verified

June 1, 2025

Enrollment Period

2.5 years

First QC Date

January 12, 2023

Last Update Submit

March 9, 2026

Conditions

Outcome Measures

Primary Outcomes (1)

  • difference in comfort score between the two groups: The comfort score will be evaluated by the French version of the pain scale of the Edmonton Symptom Assessment System

    The comfort score will be evaluated by the French version of the pain scale of the Edmonton Symptom Assessment System. The severity of each symptom was rated from 0 to 10 (0 = no symptom, 10 = worst possible intensity

    betwen the baseline and day 17

Study Arms (2)

hypnosis

patients in the hypnosis group will perform self-hypnosis sessions

Other: hypnosis

hypnosis with aromatherapy

patients in the hypnosis with aromatherapy group will perform self-hypnosis sessions with inhalation of an essential oil

Other: Hypnosis with aromatherapy

Interventions

The hypnosis session involves the following steps: 1. Preparation for the activation of the hypnotic trance 2. Activation of the hypnotic trance 3. Deepening the hypnotic trance 4. Maintaining hypnotic trance 5. Coming out of the hypnotic trance

hypnosis

for patients in the hypnosis with aromatherapy group, before starting the hypnosis session, they will first choose an essential oil among the 5 proposed. They will pour a drop on their wrist then they will rub it and inhale deeply. The hypnosis session involves the following steps: 1. Preparation for the activation of the hypnotic trance 2. Activation of the hypnotic trance 3. Deepening the hypnotic trance 4. Maintaining hypnotic trance 5. Coming out of the hypnotic trance

hypnosis with aromatherapy

Eligibility Criteria

Age18 Years+
Sexall
Healthy VolunteersNo
Age GroupsAdult (18-64), Older Adult (65+)
Sampling MethodNon-Probability Sample
Study Population

Patients coming to HDJ or hospitalized in a conventional medical oncology unit, monitored from the 1st line of chemotherapy and taken care of by the mobile palliative care support team (EMASP)

You may qualify if:

  • Patients aged ≥18 years
  • Patients followed in medical oncology and by the mobile palliative care support team
  • From the first line of chemotherapy
  • Patient requiring one of the following procedures:
  • Blood samples via a central catheter with a percutaneous implantable chamber, with a Huber needle
  • Peripheral venous samples
  • Change of dressing for cancerous lesion
  • Complete toilet in bed
  • Patients who have given their consent
  • Patient affiliated with a social security scheme

You may not qualify if:

  • Protected person under guardianship or curatorship,
  • Person deprived of liberty
  • Person unable to express consent
  • Pregnant woman and breastfeeding woman
  • History of allergy or intolerance to essential oils
  • Patients with cognitive or language disorders that make it impossible to answer the questionnaires
  • Psychotic disorders

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Study Sites (1)

Centre Hospitalier Intercommunal de Créteil

Créteil, 94000, France

RECRUITING

MeSH Terms

Conditions

Neoplasms

Interventions

HypnosisAromatherapy

Intervention Hierarchy (Ancestors)

Mind-Body TherapiesComplementary TherapiesTherapeuticsPsychotherapyBehavioral Disciplines and ActivitiesPhytotherapySensory Art Therapies

Central Study Contacts

Study Design

Study Type
observational
Observational Model
COHORT
Time Perspective
PROSPECTIVE
Sponsor Type
OTHER
Responsible Party
SPONSOR

Study Record Dates

First Submitted

January 12, 2023

First Posted

February 6, 2023

Study Start

April 10, 2024

Primary Completion (Estimated)

October 10, 2026

Study Completion (Estimated)

October 10, 2026

Last Updated

March 11, 2026

Record last verified: 2025-06

Data Sharing

IPD Sharing
Will not share

Locations