NCT05713305

Brief Summary

Timely interventions may reduce the occurrence of post-traumatic stress disorder (PTSD) in ICU medical staff. Existing research suggests that either self-learning psychological relief methods or seeking online counseling or therapy from professional psychotherapists during the SARS-CoV-2 Omicron outbreak has the potential to alleviate the emotional distress and promote the physical and mental health of health care workers. Web-based online mental health interventions complemented by joint effective mental health advice can further reduce harmful negative effects.

Trial Health

87
On Track

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Enrollment
110

participants targeted

Target at P50-P75 for not_applicable

Timeline
Completed

Started Jan 2023

Shorter than P25 for not_applicable

Geographic Reach
1 country

1 active site

Status
completed

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

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Study Timeline

Key milestones and dates

First Submitted

Initial submission to the registry

January 18, 2023

Completed
Same day until next milestone

Study Start

First participant enrolled

January 18, 2023

Completed
19 days until next milestone

First Posted

Study publicly available on registry

February 6, 2023

Completed
4 months until next milestone

Primary Completion

Last participant's last visit for primary outcome

June 20, 2023

Completed
Same day until next milestone

Study Completion

Last participant's last visit for all outcomes

June 20, 2023

Completed
Last Updated

August 5, 2024

Status Verified

January 1, 2023

Enrollment Period

5 months

First QC Date

January 18, 2023

Last Update Submit

August 1, 2024

Conditions

Outcome Measures

Primary Outcomes (1)

  • Changes in medical staff DASS-21( Depression Anxiety Stress Scale 21) after 28 days of intervention

    DASS-21 changes( 0-63), The larger the score, the worse the result

    28 days after intervention

Secondary Outcomes (7)

  • Proportion of depression and anxiety problems among different types of staff

    28 days after intervention

  • The degrees to which depression and anxiety problems occur in different types of staff

    28 days after intervention

  • Incidence of posttraumatic stress disorder

    28 days after intervention

  • Well-being was measured with the WHO-5 well-being index

    28 days after intervention

  • Improvement in sleep quality

    28 days after intervention

  • +2 more secondary outcomes

Study Arms (2)

Intervention group

EXPERIMENTAL

Daily members of the intervention group were thought to provide three different forms of daily sessions each day, averaging 10-20 minutes. These sessions included psycho-educational and cognitive-behavioral exercises, music therapy, sleep hygiene, stress relief methods. Weekly online lecture sessions presented by professional mental health therapists. In-depth interviews are conducted both before and after the experiment to explore the feasibility of the intervention

Procedure: Online-based self-help psychological intervention

Control group

PLACEBO COMPARATOR

They will receive official mental health recommendations on how to cope mentally with the pandemic. These recommendations inform about the importance of a daily structure, social contact, acceptance of negative emotions and strengthening of positive emotions, and stimulus control to assimilate SARS-CoV-2 Omicron-related news. In-depth interviews are conducted both before and after the experiment to explore the feasibility of the intervention

Procedure: Provide online mental health knowledge

Interventions

Daily members of the intervention group were thought to provide three different forms of daily sessions each day, averaging 10-20 minutes. These sessions included psycho-educational and cognitive-behavioral exercises, music therapy, sleep hygiene, stress relief methods. Weekly online lecture sessions presented by professional mental health therapists

Intervention group

They will receive official mental health recommendations on how to cope mentally with the pandemic. These recommendations inform about the importance of a daily structure, social contact, acceptance of negative emotions and strengthening of positive emotions, and stimulus control to assimilate SARS-CoV-2 Omicron-related news

Control group

Eligibility Criteria

Age18 Years+
Sexall
Healthy VolunteersNo
Age GroupsAdult (18-64), Older Adult (65+)

You may qualify if:

  • Age 18 years or older
  • Non-ICU professional staff providing direct health care services to critically ill SARS-CoV-2 Omicron patients in the ICU
  • Signing the informed consent form

You may not qualify if:

  • No reported acute suicidal tendencies
  • No history of psychotic or dissociative symptoms
  • Pregnancy or lactation
  • Major family changes within the last 12 weeks( For e.g. death of immediate family member)
  • Participated in other clinical trials

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Study Sites (1)

The Second Affiliated Hospital of Zhejiang University anesthesiology department

Hangzhou, Zhejiang, 310000, China

Location

MeSH Terms

Conditions

COVID-19Anxiety Disorders

Condition Hierarchy (Ancestors)

Pneumonia, ViralPneumoniaRespiratory Tract InfectionsInfectionsVirus DiseasesCoronavirus InfectionsCoronaviridae InfectionsNidovirales InfectionsRNA Virus InfectionsLung DiseasesRespiratory Tract DiseasesMental Disorders

Study Design

Study Type
interventional
Phase
not applicable
Allocation
RANDOMIZED
Masking
TRIPLE
Who Masked
CARE PROVIDER, INVESTIGATOR, OUTCOMES ASSESSOR
Purpose
TREATMENT
Intervention Model
PARALLEL
Sponsor Type
OTHER
Responsible Party
SPONSOR

Study Record Dates

First Submitted

January 18, 2023

First Posted

February 6, 2023

Study Start

January 18, 2023

Primary Completion

June 20, 2023

Study Completion

June 20, 2023

Last Updated

August 5, 2024

Record last verified: 2023-01

Locations