Dexmedetomidine in Postoperative Analgesia
Any
Comparison Between Effect of Addition of Dexamethasone and Dexmedetomidine in Combination With Bupivacaine for Pain Relief After Shoulder Arthroscopic Surgeries
1 other identifier
interventional
100
1 country
1
Brief Summary
There is a high incidence reaching up to 45%; of severe intraoperative and postoperative pain associated with arthroscopic shoulder surgery, which is often significant enough to interfere with initial recovery and rehabilitation.Various peripheral nerve blocks have been used to reduce intraoperative anesthetic requirements to improve rapid recovery and reduce postoperative pain.
Trial Health
Trial Health Score
Automated assessment based on enrollment pace, timeline, and geographic reach
participants targeted
Target at P50-P75 for phase_2
Started Aug 2023
1 active site
Health score is calculated from publicly available data and should be used for screening purposes only.
Trial Relationships
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Study Timeline
Key milestones and dates
First Submitted
Initial submission to the registry
January 21, 2023
CompletedFirst Posted
Study publicly available on registry
January 30, 2023
CompletedStudy Start
First participant enrolled
August 1, 2023
CompletedPrimary Completion
Last participant's last visit for primary outcome
May 15, 2025
CompletedStudy Completion
Last participant's last visit for all outcomes
May 20, 2025
CompletedMay 21, 2025
November 1, 2024
1.8 years
January 21, 2023
May 19, 2025
Conditions
Outcome Measures
Primary Outcomes (1)
numerical rating pain scale
graded from 0 to 10 (0 = no pain, 10 = the worst possible pain)
24 hours
Secondary Outcomes (1)
complications
24 hours
Study Arms (2)
dexamethasone group
ACTIVE COMPARATORpatients will receive dexamethasone with bupivacaine before general anaesthesia
dexmedetomidine group
ACTIVE COMPARATORpatients will receive dexemedetomidine with bupivacaine before general anaesthesia
Interventions
Dexmedetomidine will be given with bupivaciane for postoperative pain control
Eligibility Criteria
You may qualify if:
- Patients undergoing elective shoulder arthroscopy under general anesthesia
You may not qualify if:
- Contraindications to regional block (coagulopathy, infection at the needle insertion site, or diaphragmatic paralysis).
- Altered conscious level.
- Pregnancy. .Body mass index (BMI \> 35).
- Patients who have difficulty understanding the study protocol
- Patients who have any known contraindication to study medications
- Patient refusal.
Contact the study team to confirm eligibility.
Sponsors & Collaborators
Study Sites (1)
Assiut University Hospital
Asyut, 71516, Egypt
MeSH Terms
Conditions
Interventions
Condition Hierarchy (Ancestors)
Intervention Hierarchy (Ancestors)
Study Officials
- PRINCIPAL INVESTIGATOR
ahmed abdelsabour, lecturer
Assiut University
Study Design
- Study Type
- interventional
- Phase
- phase 2
- Allocation
- RANDOMIZED
- Masking
- TRIPLE
- Who Masked
- PARTICIPANT, CARE PROVIDER, OUTCOMES ASSESSOR
- Purpose
- TREATMENT
- Intervention Model
- PARALLEL
- Sponsor Type
- OTHER
- Responsible Party
- PRINCIPAL INVESTIGATOR
- PI Title
- lecturer
Study Record Dates
First Submitted
January 21, 2023
First Posted
January 30, 2023
Study Start
August 1, 2023
Primary Completion
May 15, 2025
Study Completion
May 20, 2025
Last Updated
May 21, 2025
Record last verified: 2024-11
Data Sharing
- IPD Sharing
- Will not share