NCT05699629

Brief Summary

To evaluate the biomarkers for the prognosis of coronary heart disease, patients with coronary heart disease will be recruited and followed up for at least 2 years.

Trial Health

77
On Track

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Enrollment
50,000

participants targeted

Target at P75+ for all trials

Timeline
9mo left

Started Jan 2022

Longer than P75 for all trials

Geographic Reach
1 country

1 active site

Status
recruiting

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

Click on a node to explore related trials.

Study Timeline

Key milestones and dates

Study Progress86%
Jan 2022Jan 2027

Study Start

First participant enrolled

January 21, 2022

Completed
12 months until next milestone

First Submitted

Initial submission to the registry

January 9, 2023

Completed
17 days until next milestone

First Posted

Study publicly available on registry

January 26, 2023

Completed
4 years until next milestone

Primary Completion

Last participant's last visit for primary outcome

January 21, 2027

Expected
Same day until next milestone

Study Completion

Last participant's last visit for all outcomes

January 21, 2027

Last Updated

February 13, 2023

Status Verified

February 1, 2023

Enrollment Period

5 years

First QC Date

January 9, 2023

Last Update Submit

February 9, 2023

Conditions

Coronary Heart DiseaseMyocardial Infarction

Outcome Measures

Primary Outcomes (1)

  • major adverse cardiovascular events

    all-cause mortality, cardiovascular mortality, ischemic stroke, heart failure and rehospitalization

    2-year outcome and long-term outcome

Eligibility Criteria

Age18 Years+
Sexall
Healthy VolunteersYes
Age GroupsAdult (18-64), Older Adult (65+)
Sampling MethodNon-Probability Sample
Study Population

Patients with coronary heart diseases undergoing coronary angiography and healthy control subjects undergoing routine physical examination in physical examination department.

You may qualify if:

  • Diagnosed as coronary heart disease or with unexplained chest pain needed to undergo coronary angiography.
  • Healthy subjects undergoing routine physical examination in the physical examination department and willing to sign informed consent will be recruited as control subjects.

You may not qualify if:

  • With malignant tumors, infectious diseases and advanced liver diseases.
  • Won't sign an inform consent.

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Study Sites (1)

Shandong First Medical University

Jinan, Shandong, 277500, China

RECRUITING

Biospecimen

Retention: SAMPLES WITH DNA

blood and fecal samples

MeSH Terms

Conditions

Coronary DiseaseMyocardial Infarction

Condition Hierarchy (Ancestors)

Myocardial IschemiaHeart DiseasesCardiovascular DiseasesVascular DiseasesInfarctionIschemiaPathologic ProcessesPathological Conditions, Signs and SymptomsNecrosis

Study Officials

  • Tao Xu, Dr.

    Shandong First Medical University

    STUDY CHAIR

Central Study Contacts

Rong Huang, Dr.

CONTACT

18854125717huangrong9277@163.com

Study Design

Study Type
observational
Observational Model
COHORT
Time Perspective
PROSPECTIVE
Sponsor Type
OTHER
Responsible Party
SPONSOR

Study Record Dates

First Submitted

January 9, 2023

First Posted

January 26, 2023

Study Start

January 21, 2022

Primary Completion (Estimated)

January 21, 2027

Study Completion (Estimated)

January 21, 2027

Last Updated

February 13, 2023

Record last verified: 2023-02

Data Sharing

IPD Sharing
Will not share

Locations

CN(1)