A New Risk Score for Predicting 1-year Mortality in Older r Maintenance Hemodialysis Patients.

NCT05699447 | Completed

• 1 other identifier: 2022-P2-385-01
• Study Type: observational
• Target: 1,500
• Locations: 0 countries
• Sites: N/A

Brief Summary

The goal of this retrospective observational cohort study is to analysis the 1-year mortality in older patients undergoing maintenance hemodialysis. The main question it aims to answer is to explore the risk factors affecting the mortality of older patients undergoing maintenance hemodialysis and establish a risk prediction score. Data of older patients (age ≥65 years old) undergoing maintenance hemodialysis were collected from 2012-1-December 31, 2014, with data from Beijing Blood Purification Quality Control and Improvement Center (BJHDQCIC). Logistic regression model was used to evaluate the 1-year mortality and the influence of predictive factors. Internal validation of the model was performed using the bootstrap 1000 repeat sampling method. Area under receiver operating characteristic curve (AUC) was used to evaluate the predictive ability of the model.

Conditions

Maintenance Hemodialysis; Older Patient

Keywords

Older patients; maintenance hemodialysis; mortality; risk prediction score.

Outcome Measures

Primary Outcomes (1)

• the 1-year mortality in older patients undergoing maintenance hemodialysis

  Data of older patients (age ≥65 years old) undergoing maintenance hemodialysis were collected from 2012-1-December 31, 2014, with data from Beijing Blood Purification Quality Control and Improvement Center (BJHDQCIC).

Eligibility Criteria

• Age: 65 Years+
• Sex: all
• Healthy Volunteers: No
• Age Groups: Older Adult (65+)
• Sampling Method: Non-Probability Sample

Study Population

Data of older patients (age ≥65 years old) undergoing maintenance hemodialysis were collected from 2012-1-December 31, 2014, with data from Beijing Blood Purification Quality Control and Improvement Center (BJHDQCIC).

You may qualify if:

• Age ≥65 years.
• More than 6-month history of hemodialysis,the frequency is 3 times a week, and the dialysis time is 4 hours each.
• The dialysate Ca concentration was 1.5 mmol/L and the bicarbonate level was 32 -- 35 mmol/L.

You may not qualify if:

• Lack of demographic information, clinical history, or relevant laboratory values (including pre-dialysis serum calcium, phosphorus, iPTH, haemoglobin, albumin, creatinine, total cholesterol, and Kt/v for urea).

Sponsors & Collaborators

• Beijing Friendship Hospital: lead

Study Design

• Study Type: observational
• Observational Model: COHORT
• Time Perspective: RETROSPECTIVE
• Sponsor Type: OTHER
• Responsible Party: PRINCIPAL INVESTIGATOR
• PI Title: professor

Study Record Dates

• First Submitted: January 17, 2023
• First Posted: January 26, 2023
• Study Start: November 28, 2022
• Primary Completion: January 10, 2023
• Study Completion: January 16, 2023
• Last Updated: January 26, 2023

Record last verified: 2023-01