NCT05695872

Brief Summary

The study is a randomized controlled clinical trial, following the Consolidated Standards of Reporting Trials (CONSORT) guidelines. The study is intended to compare between the subtarsal approach, conventional transconjuctival approach and the Y- modification of the transconjuctival approach in the management of zygomatico-maxillay complex fracture.

Trial Health

87
On Track

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Enrollment
24

participants targeted

Target at below P25 for not_applicable

Timeline
Completed

Started Aug 2022

Shorter than P25 for not_applicable

Geographic Reach
1 country

1 active site

Status
completed

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

Click on a node to explore related trials.

Study Timeline

Key milestones and dates

Study Start

First participant enrolled

August 26, 2022

Completed
5 months until next milestone

First Submitted

Initial submission to the registry

January 11, 2023

Completed
14 days until next milestone

First Posted

Study publicly available on registry

January 25, 2023

Completed
7 days until next milestone

Primary Completion

Last participant's last visit for primary outcome

February 1, 2023

Completed
4 days until next milestone

Study Completion

Last participant's last visit for all outcomes

February 5, 2023

Completed
Last Updated

May 9, 2023

Status Verified

May 1, 2023

Enrollment Period

5 months

First QC Date

January 11, 2023

Last Update Submit

May 8, 2023

Conditions

Outcome Measures

Primary Outcomes (3)

  • accessibility to the fracture site

    Adequate exposure provided by the incision and accessiblity to proper fracture reduction and fixation was assigned as Yes or No

    intraoperative

  • esthetic appearance and scarring

    Postoperative scarring was recorded as noticeable or unnoticeable

    6 weeks postoperative

  • radiographic verification of adequacy of fracture reduction

    computed tomography was requested for adequacy of fracture reduction assessment and this outcome was assigned as Yes or No

    immediate postoperative

Secondary Outcomes (3)

  • The duration for exposure of the fracture site

    intraoperative

  • postoperative pain

    at 24 hours and 1 week

  • sensory nerve function

    3 months postoperative

Study Arms (3)

subtarsal approach

ACTIVE COMPARATOR
Procedure: subtarsal approach

conventional transconjunctival approach

ACTIVE COMPARATOR
Procedure: conventional transconjunctival approach

transconjunctival approach with Y- modification

ACTIVE COMPARATOR
Procedure: transconjunctival approach with Y- modification

Interventions

surgical approach

subtarsal approach

surgical approach

conventional transconjunctival approach

surgical approach

transconjunctival approach with Y- modification

Eligibility Criteria

Age20 Years - 50 Years
Sexall
Healthy VolunteersNo
Age GroupsAdult (18-64)

You may qualify if:

  • Patients with ZMC fractures requiring open reduction and internal fixation.
  • Adult patients aged between 20 and 50 years with no gender predilection.

You may not qualify if:

  • An existing laceration in the inferior and lateral periorbital site.
  • Infection at the fracture line.
  • Comminuted fracture with bone loss.
  • Acute and chronic conjunctival diseases.

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Study Sites (1)

Faculty of Dentistry, Alexandria University

Alexandria, 21526, Egypt

Location

Related Publications (1)

  • Melek LN, Noureldin MG. Zygomaticomaxillary complex fractures: finding the least complicated surgical approach (A Randomized Clinical Trial). BMC Oral Health. 2023 Aug 4;23(1):539. doi: 10.1186/s12903-023-03249-8.

MeSH Terms

Conditions

Zygomatic Fractures

Condition Hierarchy (Ancestors)

Maxillofacial InjuriesFacial InjuriesCraniocerebral TraumaTrauma, Nervous SystemNervous System DiseasesSkull FracturesFractures, BoneWounds and Injuries

Study Design

Study Type
interventional
Phase
not applicable
Allocation
RANDOMIZED
Masking
NONE
Purpose
TREATMENT
Intervention Model
PARALLEL
Sponsor Type
OTHER
Responsible Party
PRINCIPAL INVESTIGATOR
PI Title
Associate Professor of Oral and Maxillofacial Surgery

Study Record Dates

First Submitted

January 11, 2023

First Posted

January 25, 2023

Study Start

August 26, 2022

Primary Completion

February 1, 2023

Study Completion

February 5, 2023

Last Updated

May 9, 2023

Record last verified: 2023-05

Data Sharing

IPD Sharing
Will not share

Locations