NCT05695755

Brief Summary

The present study aims to:

  1. 1.Estimate the prevalence of Postural Tachycardia Syndrome and vasovagal syncope among adults patients attend the Internal Medicine Clinic and ICU in period from 11/2022 to 10/2023
  2. 2.Detect of causes and the relationship between POTS and vasovagal syncope and serum electrolytes, and serum cortisol.

Trial Health

43
At Risk

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Trial has exceeded expected completion date
Enrollment
50

participants targeted

Target at P25-P50 for all trials

Timeline
Completed

Started Nov 2022

Shorter than P25 for all trials

Geographic Reach
1 country

1 active site

Status
unknown

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

Click on a node to explore related trials.

Study Timeline

Key milestones and dates

Study Start

First participant enrolled

November 1, 2022

Completed
2 months until next milestone

First Submitted

Initial submission to the registry

January 13, 2023

Completed
12 days until next milestone

First Posted

Study publicly available on registry

January 25, 2023

Completed
7 months until next milestone

Primary Completion

Last participant's last visit for primary outcome

September 1, 2023

Completed
1 month until next milestone

Study Completion

Last participant's last visit for all outcomes

October 1, 2023

Completed
Last Updated

January 25, 2023

Status Verified

January 1, 2023

Enrollment Period

10 months

First QC Date

January 13, 2023

Last Update Submit

January 13, 2023

Conditions

Outcome Measures

Primary Outcomes (1)

  • Estimate the prevalence of Postural Tachycardia Syndrome and vasovagal syncope

    Estimate the prevalence of Postural Tachycardia Syndrome and vasovagal syncope among adults patients attend the Internal Medicine Clinic and IC Detect of causes and the relationship between POTS and vasovagal syncope and serum electrolytes, and serum cortisol.

    11/2022 to 10/2023

Interventions

echocardiography, serum electrolytes and cortisol level for all patients

Eligibility Criteria

Age18 Years+
Sexall
Healthy VolunteersNo
Age GroupsAdult (18-64), Older Adult (65+)
Sampling MethodNon-Probability Sample
Study Population

patients with inclusion criteria attending Internal Medicine Department, The Main Assiut University Hospital

You may qualify if:

  • Patient Above 18 years.
  • Patient fulfilling diagnostic criteria of POTS increase heart rate from supine position to active standing by \> 30 beat per minute within 10 minutes and positive poor mans man tilt table test.
  • Patient with History of vasovagal syncope

You may not qualify if:

  • Age Below 18 Yrs old
  • patient with specific cardiac diseases
  • Patient with Neurologic disorders
  • patients on drugs that affect vasomotor tone of blood vessels

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Study Sites (1)

Assiut University

Asyut, 71515, Egypt

RECRUITING

Related Publications (1)

  • Freeman R, Wieling W, Axelrod FB, Benditt DG, Benarroch E, Biaggioni I, Cheshire WP, Chelimsky T, Cortelli P, Gibbons CH, Goldstein DS, Hainsworth R, Hilz MJ, Jacob G, Kaufmann H, Jordan J, Lipsitz LA, Levine BD, Low PA, Mathias C, Raj SR, Robertson D, Sandroni P, Schatz IJ, Schondorf R, Stewart JM, van Dijk JG. Consensus statement on the definition of orthostatic hypotension, neurally mediated syncope and the postural tachycardia syndrome. Auton Neurosci. 2011 Apr 26;161(1-2):46-8. doi: 10.1016/j.autneu.2011.02.004. Epub 2011 Mar 9. No abstract available.

    PMID: 21393070BACKGROUND

MeSH Terms

Conditions

Postural Orthostatic Tachycardia Syndrome

Interventions

Caves

Condition Hierarchy (Ancestors)

Orthostatic IntolerancePrimary DysautonomiasAutonomic Nervous System DiseasesNervous System Diseases

Intervention Hierarchy (Ancestors)

Geological PhenomenaPhysical PhenomenaEnvironmentEcological and Environmental PhenomenaBiological PhenomenaEnvironment and Public Health

Central Study Contacts

Hossam M Abdelraheem

CONTACT

Hala Kh Elshreef

CONTACT

Study Design

Study Type
observational
Observational Model
OTHER
Time Perspective
CROSS SECTIONAL
Sponsor Type
OTHER
Responsible Party
PRINCIPAL INVESTIGATOR
PI Title
Doctor

Study Record Dates

First Submitted

January 13, 2023

First Posted

January 25, 2023

Study Start

November 1, 2022

Primary Completion

September 1, 2023

Study Completion

October 1, 2023

Last Updated

January 25, 2023

Record last verified: 2023-01

Locations