NCT05693948

Brief Summary

This study is conducted to evaluate the effectiveness of topical serum X containing arbutin and glutathione for skin brightening. The study duration is 12 weeks and the skin assessment will be carried out at baseline, week 4, 8 and week 12.The main questions this study aims to answer are:

  1. 1.The skin brightening effect of the product on facial skin.
  2. 2.To observe any adverse effect occurrence with the usage of the product.

Trial Health

87
On Track

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Enrollment
34

participants targeted

Target at P25-P50 for not_applicable healthy

Timeline
Completed

Started Sep 2022

Typical duration for not_applicable healthy

Geographic Reach
1 country

1 active site

Status
completed

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

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Study Timeline

Key milestones and dates

Study Start

First participant enrolled

September 1, 2022

Completed
4 months until next milestone

First Submitted

Initial submission to the registry

January 11, 2023

Completed
12 days until next milestone

First Posted

Study publicly available on registry

January 23, 2023

Completed
4 months until next milestone

Primary Completion

Last participant's last visit for primary outcome

May 31, 2023

Completed
3 months until next milestone

Study Completion

Last participant's last visit for all outcomes

September 1, 2023

Completed
Last Updated

November 29, 2023

Status Verified

November 1, 2023

Enrollment Period

9 months

First QC Date

January 11, 2023

Last Update Submit

November 27, 2023

Conditions

Healthy

Keywords

AestheticCosmetic

Outcome Measures

Primary Outcomes (2)

  • Changes in skin tone from baseline and at week 4, week 8, and week 12 after usage of serum X.

    Skin tone will be assessed using JANUS III skin analyzer

    Baseline and at week 4, week 8, and week 12

  • Adverse effect after using serum X

    Based on adverse effect occurrence on participants that occur during study period (12 weeks

    Week 12

Study Arms (1)

Serum X

EXPERIMENTAL

Participants will used serum X twice daily for 12 weeks

Other: Other: Serum X

Interventions

Other: Serum XOTHER

Serum X contain arbutin and glutathione

Serum X

Eligibility Criteria

Age18 Years - 30 Years
Sexall
Healthy VolunteersYes
Age GroupsAdult (18-64)

You may qualify if:

  • Malaysia citizen
  • Male and female (age 18-30 years old)

You may not qualify if:

  • Participant with severe acne skin condition
  • Participant who is taking isotretinoin, immunocompromised patients and received laser and light treatment within the last three months
  • Participant who undergo whitening or cosmetic treatments such as botox and dermal fillers within the previous six month
  • Participant with a history of facial surgery such as facelift or nose reshaping
  • Participant with history of allergies to any ingredient in the study product
  • Participant who is pregnant or plan to get pregnant

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Study Sites (1)

Ungku Shahrin Medical Aesthetic Research & Innovation (USMARI) Centre

Petaling Jaya, Selangor, 47810, Malaysia

Location

Study Design

Study Type
interventional
Phase
not applicable
Allocation
NA
Masking
NONE
Purpose
OTHER
Intervention Model
SINGLE GROUP
Sponsor Type
INDUSTRY
Responsible Party
SPONSOR

Study Record Dates

First Submitted

January 11, 2023

First Posted

January 23, 2023

Study Start

September 1, 2022

Primary Completion

May 31, 2023

Study Completion

September 1, 2023

Last Updated

November 29, 2023

Record last verified: 2023-11

Data Sharing

IPD Sharing
Will not share

Locations

MY(1)