A Supervised Prehabilitation Program for Patients With Pancreatic Cancer

NCT05692323 | Active Not Recruiting Results DMC

• 1 other identifier: IIT2021-18-CHANG-PREHAB
• Study Type: interventional
• Target: 16
• Locations: 1 country
• Sites: 1

Brief Summary

The purpose of this study is to assess the use of an exercise program in people with pancreatic cancer.

Conditions

Pancreas Cancer

Keywords

Exercise; Prehabilitation

Outcome Measures

Primary Outcomes (1)

• PREHAB Feasibility

  PREHAB Program feasibility will be measured by tracking participant attendance at PREHAB sessions. PREHAB will be considered feasible if 50% of participants attend at least 60% of scheduled sessions. PREHAB session feasibility is defined as at least 50% of participants attending at least 60% of scheduled sessions

  From Baseline to 3 Months

Secondary Outcomes (1)

• PREHAB Program Safety

  From Baseline to 3 Months

Study Arms (1)

Supervised Prehabilitation Exercise Program

EXPERIMENTAL

Other: PREHAB

Interventions

PREHAB OTHER

6-week supervised PREHAB program. Each week of the program consists of 3 x 1 hour supervised training sessions made up of moderate intensity aerobic training and resistance training. In addition to the supervised sessions, patients will be instructed to accumulate a total of 150 minutes per week of moderate aerobic training at home which is measured by a wrist worn FitBit device.

Supervised Prehabilitation Exercise Program

Eligibility Criteria

• Age: 18 Years+
• Sex: all
• Healthy Volunteers: No
• Age Groups: Adult (18-64), Older Adult (65+)

You may qualify if:

• Pancreatic cancer diagnosis (any stage)
• Age ≥ 18 years
• Independent ambulation and activities of daily living (Discretion of referring/ treating oncologist)
• Godin-Shephard Leisure-Time Physical Activity Questionnaire score of ≤ 23
• Physically able to complete functional assessments including 6-minute walk test, hand grip strength, short performance physical battery and performance metrics
• Answers no to all questions on PAR-Q OR is cleared to participate by their treating oncologist
• Ability to read, write and understand English
• Written informed consent obtained from subject and ability for subjects to comply with the requirements of the study
• Access to a smart device capable of Fitbit syncing and accessing the online Pain portal (www.painguide.com)

You may not qualify if:

• Has undergone or plans to undergo resection surgery prior to projected completion of PREHAB exercise intervention
• Current pregnancy
• Using a pacemaker, implantable cardiac defibrillator, neurostimulator, cochlear implants (removable hearing aids permitted), or other electronic medical equipment, unless the PI deems study participation safe.

Sponsors & Collaborators

• Cedars-Sinai Medical Center: lead

Study Sites (1)

Cedars-Sinai Medical Center

Los Angeles, California, 90048, United States

Location

MeSH Terms

Conditions

Pancreatic Neoplasms; Motor Activity

Condition Hierarchy (Ancestors)

Digestive System Neoplasms; Neoplasms by Site; Neoplasms; Endocrine Gland Neoplasms; Digestive System Diseases; Pancreatic Diseases; Endocrine System Diseases; Behavior

Results Point of Contact

• Title: Dr. Philip Chang
• Organization: Cedars-Sinai Medical Center

philip.chang@csmc.edu

310-467-4498

Study Officials

• Philip Chang, DO

  Cedars-Sinai Medical Center

  PRINCIPAL INVESTIGATOR

Publication Agreements

• PI is Sponsor Employee: Yes

Study Design

• Study Type: interventional
• Phase: not applicable
• Allocation: NA
• Masking: NONE
• Purpose: SUPPORTIVE CARE
• Intervention Model: SINGLE GROUP
• Sponsor Type: OTHER
• Responsible Party: PRINCIPAL INVESTIGATOR
• PI Title: Sponsor-Investigator

Study Record Dates

• First Submitted: January 11, 2023
• First Posted: January 20, 2023
• Study Start: May 15, 2023
• Primary Completion: October 15, 2025
• Study Completion (Estimated): April 1, 2027
• Last Updated: April 15, 2026
• Results First Posted: April 15, 2026

Record last verified: 2026-04

Data Sharing

• IPD Sharing: Will not share

Locations

US (1)